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HRT Oestrogens (P19)

S Jill Stocks, Evangelos Kontopantelis, Artur Akbarov, Sarah Rodgers, Anthony J Avery, Darren M Aschroft

Type
Drug
ID
PH679
Version ID
1358
Data Sources
Valid event data range
Start - 01/02/2013
Sex
Female, Male
Agreement Date
2015-11-03
Coding system
GPRD product codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Study question:

What is the prevalence of different types of potentially hazardous prescribing in general practice in the United Kingdom, and what is the variation between practices?

Methods:

A cross sectional study included all adult patients potentially at risk of a prescribing or monitoring error defined by a combination of diagnoses and prescriptions in 526 general practices contributing to the Clinical Practice Research Datalink (CPRD) up to 1 April 2013. Primary outcomes were the prevalence of potentially hazardous prescriptions of anticoagulants, anti-platelets, NSAIDs, β blockers, glitazones, metformin, digoxin, antipsychotics, combined hormonal contraceptives, and oestrogens and monitoring by blood test less frequently than recommended for patients with repeated prescriptions of angiotensin converting enzyme inhibitors and loop diuretics, amiodarone, methotrexate, lithium, or warfarin.

Study answer and limitations:

49 927 of 949 552 patients at risk triggered at least one prescribing indicator (5.26%, 95% confidence interval 5.21% to 5.30%) and 21 501 of 182 721 (11.8%, 11.6% to 11.9%) triggered at least one monitoring indicator. The prevalence of different types of potentially hazardous prescribing ranged from almost zero to 10.2%, and for inadequate monitoring ranged from 10.4% to 41.9%. Older patients and those prescribed multiple repeat medications had significantly higher risks of triggering a prescribing indicator whereas younger patients with fewer repeat prescriptions had significantly higher risk of triggering a monitoring indicator. There was high variation between practices for some indicators. Though prescribing safety indicators describe prescribing patterns that can increase the risk of harm to the patient and should generally be avoided, there will always be exceptions where the indicator is clinically justified. Furthermore there is the possibility that some information is not captured by CPRD for some practices—for example, INR results in patients receiving warfarin.

What this study adds:

The high prevalence for certain indicators emphasises existing prescribing risks and the need for their appropriate consideration within primary care, particularly for older patients and those taking multiple medications. The high variation between practices indicates potential for improvement through targeted practice level intervention.

Publications

  • S Jill Stocks, Evangelos Kontopantelis, Artur Akbarov, Sarah Rodgers, Anthony J Avery, Darren M Ashcroft, Examining variations in prescribing safety in UK general practice cross sectional study using the Clinical Practice Research Datalink. BMJ, 351(h5501), 2015.

Clinical Code List

Rows: 234
Code Description Coding System (CPRD_product_code) Entity type Category
10052 Progynova TS 50micrograms/24hours transdermal patches (Bayer Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
10076 Estradot 75micrograms/24hours patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
10096 Estradot 100micrograms/24hours patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
10126 Estradot 25micrograms/24hours patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
10180 Estradot 50micrograms/24hours patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
10946 Menorest 50 patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
10967 Menorest 37.5 patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
11157 Estradiol and (estradiol with dydrogesterone) 1mg with (1mg with 10mg) tablets CPRD_product_code res25: P19_HRT_oestrogens drug
11297 Estradiol valerate and (estradiol valerate with levonorgestrel) 2mg with (2mg with 75micrograms) tab CPRD_product_code res25: P19_HRT_oestrogens drug
11363 Estradiol and (estradiol with dydrogesterone) 2mg with (2mg with 20mg) tablets CPRD_product_code res25: P19_HRT_oestrogens drug
11375 Estradiol 50micrograms/24hr once weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
11430 Estradiol 25micrograms/24hr once weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
11511 Estradiol and (estradiol with dydrogesterone) 2mg with (2mg with 10 mg) tablets CPRD_product_code res25: P19_HRT_oestrogens drug
1160 Prempak-C 0.625mg/0.15mg tablets (Pfizer Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
1161 Prempak-C 1.25mg/0.15mg tablets (Pfizer Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
11642 Estradiol valerate and (estradiol valerate with levonorgestrel) 1mg with (1mg with 250micrograms) ta CPRD_product_code res25: P19_HRT_oestrogens drug
11672 Estradiol 25micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
1183 Estracombi TTS patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
11882 Estradiol 50micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
12661 Estradiol valerate with medroxyprogesterone acetate tablets CPRD_product_code res25: P19_HRT_oestrogens drug
1268 Kliofem tablets (Novo Nordisk Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
12713 Estradiol valerate and (estradiol valerate with norethisterone) 2mg with (2mg with 1 mg) tablets CPRD_product_code res25: P19_HRT_oestrogens drug
12773 Estradiol 100micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
12788 Estradiol 1mg / Norethisterone acetate 500microgram tablets CPRD_product_code res25: P19_HRT_oestrogens drug
12807 Estradiol with norethisterone acetate ( continuous combined) 2mg with 0.7mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
12907 Estradiol and (estradiol with dydrogesterone) tablets 1mg with 5mg CPRD_product_code res25: P19_HRT_oestrogens drug
12953 Estradiol 1mg / Dydrogesterone 5mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
12970 Conjugated oestrogens 1.25mg tablets and Norgestrel 150microgram tablets CPRD_product_code res25: P19_HRT_oestrogens drug
13146 Novofem tablets (Novo Nordisk Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
1331 Premarin 0.625mg tablets (Pfizer Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
13582 Menorest 75 patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
13945 Estradiol and (estradiol with levonorgestrel) 80mcg/24hrs with (50mcg+20mcg/24hr) twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
14027 Estradiol with (estradiol with norethisterone acetate) 1mg with (1mg with 1mg) tablets CPRD_product_code res25: P19_HRT_oestrogens drug
14234 Estradiol 37.5micrograms/24hours transdermal patches CPRD_product_code res25: P19_HRT_oestrogens drug
14569 Estradiol and (estradiol with norethisterone) and (estradiol) 2mg with (2mg with 1mg) tablets CPRD_product_code res25: P19_HRT_oestrogens drug
14580 Dermestril 25 patches (ProStrakan Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
14596 Estradiol and (estradiol with norethisterone) and (estradiol) triphasic forte 4mg with (4mg with 1mg CPRD_product_code res25: P19_HRT_oestrogens drug
14792 Estradiol 50micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
14812 Estradiol with (estradiol with norethisterone acetate) 50mcg/24 hr with (50mcg+170mcg/24 hr) twice w CPRD_product_code res25: P19_HRT_oestrogens drug
1488 Evorel -50 50microgram/24hr (3.2mg/unit) Transdermal patch (Janssen-Cilag Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
1489 Evorel -75 75microgram/24 hr(4.8mg/unit) Transdermal patch (Janssen-Cilag Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
14950 Estradiol 50micrograms/24hours / Norethisterone 170micrograms/24hours transdermal patches CPRD_product_code res25: P19_HRT_oestrogens drug
15100 Estradiol 37.5micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
15194 Dermestril 100 patches (ProStrakan Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
15298 Estradiol 25micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
15328 Estradiol 25micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
1568 Tridestra tablets (Orion Pharma (UK) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
15869 Dermestril 50 patches (ProStrakan Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
15880 Dermestril - Septem 75 patches (ProStrakan Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
16367 Estradiol valerate 1mg / Medroxyprogesterone 2.5mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
16392 Estradiol valerate 2mg / Medroxyprogesterone 5mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
16437 Estradiol 100micrograms/24hr once weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
16443 FemTab Continuous tablets (Merck Serono Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
16493 Angeliq tablets (Bayer Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
16997 Estradiol with (estradiol with norethisterone acetate) 2mg with (2mg with 1 mg) tablets CPRD_product_code res25: P19_HRT_oestrogens drug
17529 Estradiol 2mg vaginal ring CPRD_product_code res25: P19_HRT_oestrogens drug
1760 Prempak 0.625 Tablet (Wyeth Pharmaceuticals) CPRD_product_code res25: P19_HRT_oestrogens drug
1797 Oestrogel 0.06% Gel (Aventis Pharma) CPRD_product_code res25: P19_HRT_oestrogens drug
18009 Estradiol 50micrograms/24hr once weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
18167 Estradiol valerate and (estradiol valerate with medroxyprogesterone acetate) with placebo 2mg with ( CPRD_product_code res25: P19_HRT_oestrogens drug
18218 Estradiol 100micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
18311 Estriol 250micrograms tablets CPRD_product_code res25: P19_HRT_oestrogens drug
18383 Estradiol 80micrograms/24hours transdermal patches CPRD_product_code res25: P19_HRT_oestrogens drug
18437 Estradiol 75micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
18502 Estradiol 75micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
18530 Estradiol valerate and (estradiol valerate with norgestrel) 2mg with (2mg with 500micrograms) tablet CPRD_product_code res25: P19_HRT_oestrogens drug
18600 Estradiol 75micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
1873 Climaval 1mg tablets (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
18901 Estradiol 50micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
19135 Estradiol 50mg implant (Merck Sharp & Dohme Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
19145 Estradiol 50micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
1922 Hormonin Tablet (Shire Pharmaceuticals Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
19429 Conjugat oestrogen equi and (conjugat oestrogen equi with medroxyprogesterone acetate 625 micrograms CPRD_product_code res25: P19_HRT_oestrogens drug
19432 Estradiol valerate 1mg / Medroxyprogesterone 5mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
19487 Estradot 37.5micrograms/24hours patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
19974 Estradiol 50micrograms/24hours / Levonorgestrel 7micrograms/24hours transdermal patches CPRD_product_code res25: P19_HRT_oestrogens drug
19986 Estradiol and (estradiol with levonorgestrel) 50mcg/24hrs with (50mcg+10mcg/24hrs) once weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
20135 Estradiol 75micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
20155 Estradiol 50micrograms/24hr once weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
20393 Mixogen Tablet (Organon Laboratories Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
206 Estraderm TTS 100 patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
20888 Adgyn Estro 2mg tablets (ProStrakan Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
20895 Dermestril - Septem 50 patches (ProStrakan Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
2111 Climagest 2mg tablets (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
2115 Kliovance tablets (Novo Nordisk Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
2140 FemSeven 50 patches (Teva UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
2141 Evorel -25 25microgram/24hr (1.6mg/unit) Transdermal patch (Janssen-Cilag Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
2208 Trisequens tablets (Novo Nordisk Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
2209 Livial 2.5mg tablets (Merck Sharp & Dohme Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
22335 Estradiol 100micrograms/24hr once weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
22372 Estradiol 80micrograms/24hours transdermal patches and Dydrogesterone 10mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
2262 Climaval 2mg tablets (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
22741 Conjugated oestrogens 625microgram tablets and Norgestrel 150microgram tablets CPRD_product_code res25: P19_HRT_oestrogens drug
22975 Estradiol 1mg / Drospirenone 2mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
23152 Estradiol 40micrograms/24hours transdermal patches and Dydrogesterone 10mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
2397 Evorel -100 100microgram/24 hr (6.4mg/unit) Transdermal patch (Janssen-Cilag Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
2402 Vagifem 25microgram vaginal tablets (Novo Nordisk Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
2457 Estradiol valerate 1mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
24917 Estradiol valerate 2mg / Norethisterone 700microgram tablets CPRD_product_code res25: P19_HRT_oestrogens drug
256 Tibolone 2.5mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
2597 Premarin 0.625mg/g vaginal cream (Pfizer Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
26049 Estradiol 100micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
2729 Evorel Conti patches (Janssen-Cilag Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
2766 Climesse tablets (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
28230 Clinorette tablets (ReSource Medical UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
29449 Estradiol 1mg/ml injection CPRD_product_code res25: P19_HRT_oestrogens drug
29573 Dienestrol 5mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
2977 Estradiol 50mg implant CPRD_product_code res25: P19_HRT_oestrogens drug
3002 Elleste Duet 1mg tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
3036 Cyclo-Progynova 2mg tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
3040 Estraderm MX 50 patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
3131 Femapak 40 (Abbott Healthcare Products Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
31330 Estradio; 5m/ml injection CPRD_product_code res25: P19_HRT_oestrogens drug
3179 Progynova 1mg tablets (Bayer Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
32930 Dermestril septem 25microgram/24hr Transdermal patch (Strakan Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
3387 Estraderm MX 25 patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
34174 Conjugated oestrogens equine with medroxyprogesterone acetate 625micrograms with 10mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
3423 Conjugated oestrogens 625microgram tablets CPRD_product_code res25: P19_HRT_oestrogens drug
3433 Sandrena 0.10% Gel (Organon Laboratories Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
34749 Prempak 1.25 Tablet (Wyeth Pharmaceuticals) CPRD_product_code res25: P19_HRT_oestrogens drug
35091 Oestrogel Pump-Pack 0.06% gel (Besins Healthcare (UK) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
35198 Premarin 0.3mg tablets (Pfizer Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
3530 Femoston 1/10mg tablets (Abbott Healthcare Products Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
3553 Femoston 2/10mg tablets (Abbott Healthcare Products Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
35718 Conjugated oestrogens 300microgram tablets CPRD_product_code res25: P19_HRT_oestrogens drug
35742 Estradiol 100micrograms/24hr once weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
35958 Bedol 2mg tablets (ReSource Medical UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
37033 Estradiol 75micrograms/24hours transdermal patches CPRD_product_code res25: P19_HRT_oestrogens drug
37037 Estradiol 100micrograms/24hours transdermal patches CPRD_product_code res25: P19_HRT_oestrogens drug
37692 Estradiol 25micrograms/24hours transdermal patches CPRD_product_code res25: P19_HRT_oestrogens drug
37697 Estradiol 50micrograms/24hours transdermal patches CPRD_product_code res25: P19_HRT_oestrogens drug
38932 Evorel 50 patches (Janssen-Cilag Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
38935 Evorel 25 patches (Janssen-Cilag Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
38940 Evorel 75 patches (Janssen-Cilag Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
38965 Evorel 100 patches (Janssen-Cilag Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
390 Climagest 1mg tablets (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
3960 Conjugated oestrogens 1.25mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
39622 Hormonin tablets (AMCo) CPRD_product_code res25: P19_HRT_oestrogens drug
40606 Sandrena 500microgram gel sachets (Orion Pharma (UK) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
40643 Sandrena 1mg gel sachets (Orion Pharma (UK) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
40836 Estradiol 500microgram gel sachets CPRD_product_code res25: P19_HRT_oestrogens drug
40848 Estradiol 1mg gel sachets CPRD_product_code res25: P19_HRT_oestrogens drug
41390 Estradiol with (estradiol with norethisterone acetate) twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
4207 Elleste Duet 2mg tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
4244 Evorel Sequi patches (Janssen-Cilag Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
42515 Estradiol 40micrograms/24 hourspatch CPRD_product_code res25: P19_HRT_oestrogens drug
4326 Progynova 2mg tablets (Bayer Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
4328 Elleste Solo 1mg tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
4393 Elleste Duet Conti tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
44461 Estradiol 10microgram pessaries CPRD_product_code res25: P19_HRT_oestrogens drug
44494 Vagifem 10microgram vaginal tablets (Novo Nordisk Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
4466 Progynova TS 50microgram/24hr (3.8mg/unit) Transdermal patch (Schering Health Care Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
4467 Progynova TS 100microgram/24 hr (7.6mg/unit) Transdermal patch (Schering Health Care Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
4721 Estradiol 75micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
4882 Estraderm MX 100 patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
4909 Elleste Solo 2mg tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
4956 Estradiol 1mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
49693 Vagifem 25microgram vaginal tablets (Mawdsley-Brooks & Company Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
49694 Estraderm TTS 25 patches (DE Pharmaceuticals) CPRD_product_code res25: P19_HRT_oestrogens drug
49757 FemSeven Conti patches (Lexon (UK) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
4977 Estraderm MX 75 patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
49985 Femoston-conti 0.5mg/2.5mg tablets (Abbott Healthcare Products Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
5005 Estradiol 50micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
5012 Estradiol 2mg / Norethisterone acetate 1mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
50200 Climagest 1mg tablets (Sigma Pharmaceuticals Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
5100 Estradiol 25micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
51201 Estradot 50micrograms/24hours patches (Necessity Supplies Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
51546 Climaval 2mg tablets (Lexon (UK) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
51688 Evorel Conti patches (Lexon (UK) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
5195 Femoston-conti 1mg/5mg tablets (Abbott Healthcare Products Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
51978 Estraderm MX 25 patches (Stephar (U.K.) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
52174 Estradot 50micrograms/24hours patches (Sigma Pharmaceuticals Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
52306 Femoston-conti 1mg/5mg tablets (Stephar (U.K.) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
52441 Evorel Conti patches (DE Pharmaceuticals) CPRD_product_code res25: P19_HRT_oestrogens drug
52480 Estraderm MX 25 patches (Lexon (UK) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
52632 Vagifem 25microgram vaginal tablets (Waymade Healthcare Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
52813 Nuvelle TS Phase I patches (Bayer Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
5292 Fematrix 40 patches (Abbott Healthcare Products Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
5343 Estradiol 25micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
54425 Oestrogel Pump-Pack 0.06% gel (DE Pharmaceuticals) CPRD_product_code res25: P19_HRT_oestrogens drug
54456 Estradiol valerate with norgestrel 2mg+500micrograms tablets CPRD_product_code res25: P19_HRT_oestrogens drug
55551 Estradiol 500micrograms / Dydrogesterone 2.5mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
56056 Generic Elleste Duet 1mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
56081 Generic Femoston 1/10mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
56468 Oestrogel Pump-Pack 0.06% gel (Waymade Healthcare Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
56480 Evorel Conti patches (Waymade Healthcare Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
57514 Estraderm TTS 50 patches (Waymade Healthcare Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
57548 Oestrogel Pump-Pack 0.06% gel (Sigma Pharmaceuticals Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
5755 Elleste Solo MX 40 transdermal patches (Meda Pharmaceuticals Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
57562 Sandrena 1mg gel sachets (Waymade Healthcare Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
5759 Estradiol 100micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
57590 Progynova TS 50 patches (Dowelhurst Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
57615 Livial 2.5mg tablets (Waymade Healthcare Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
58035 Generic Elleste Duet 2mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
58516 Generic Femoston 2/10mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
58575 Generic Climagest 1mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
6030 Nuvelle Continuous tablets (Bayer Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
6041 Estradiol 0.06% gel CPRD_product_code res25: P19_HRT_oestrogens drug
6059 Estradiol 100micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
60637 Climaval 1mg tablets (Lexon (UK) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
6082 FemSeven 75 patches (Teva UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
6177 FemSeven 100 patches (Teva UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
6538 FemTab 2mg tablets (Merck Serono Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
6545 FemSeven Conti patches (Teva UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
6563 Estradiol 75micrograms/24hr once weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
6601 Estradiol 25micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
6603 Estradiol with estrone and estriol tablets CPRD_product_code res25: P19_HRT_oestrogens drug
6622 Zumenon 2mg tablets (Abbott Healthcare Products Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
6793 Estradiol 40micrograms/24hours transdermal patches CPRD_product_code res25: P19_HRT_oestrogens drug
6861 Indivina 1mg/5mg tablets (Orion Pharma (UK) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
7001 Estradiol valerate 2mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
7175 Indivina 1mg/2.5mg tablets (Orion Pharma (UK) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
7242 Estradiol 0.1% gel CPRD_product_code res25: P19_HRT_oestrogens drug
7251 FemTab 1mg tablets (Merck Serono Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
7381 Estradiol 2mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
7388 Zumenon 1mg tablets (Abbott Healthcare Products Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
7615 Estradiol 25microgram pessaries CPRD_product_code res25: P19_HRT_oestrogens drug
774 Premarin 1.25mg tablets (Pfizer Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
8777 Dienestrol 1mg tablets CPRD_product_code res25: P19_HRT_oestrogens drug
8837 Estradiol 25mg implant CPRD_product_code res25: P19_HRT_oestrogens drug
9047 Fematrix 80 patches (Abbott Healthcare Products Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
9181 Estring 2mg vaginal ring (Pfizer Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
9224 Norgestrel and conjugated oestrogens (equine) 150micrograms + 625micrograms Tablet CPRD_product_code res25: P19_HRT_oestrogens drug
9235 Norgestrel and conjugated oestrogens (equine) 150micrograms + 1.25mg Tablet CPRD_product_code res25: P19_HRT_oestrogens drug
9268 Estradiol 50micrograms/24hr twice weekly patch CPRD_product_code res25: P19_HRT_oestrogens drug
932 Conjugated oestrogens 625micrograms/g vaginal cream CPRD_product_code res25: P19_HRT_oestrogens drug
9413 Estradiol valerate and (estradiol valerate with norethisterone) 1mg with (1mg with 1mg) tablets CPRD_product_code res25: P19_HRT_oestrogens drug
9649 Elleste Solo MX 80 transdermal patches (Meda Pharmaceuticals Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
9671 Indivina 2mg/5mg tablets (Orion Pharma (UK) Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
9684 Femapak 80 (Abbott Healthcare Products Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
986 Estraderm TTS 50 patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
988 Estraderm TTS 25 patches (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug
9901 Progynova TS 100micrograms/24hours transdermal patches (Bayer Plc) CPRD_product_code res25: P19_HRT_oestrogens drug
9905 FemSeven Sequi patches (Teva UK Ltd) CPRD_product_code res25: P19_HRT_oestrogens drug

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH679/version/1358/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH679/version/1358/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH679', '1358', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH679/version/1358/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH679/version/1358/export/codes/?format=json
CSV site_root/phenotypes/PH679/version/1358/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH679', '1358', api_client=client)

Version History

Version
ID
Name Owner Publish date
1358 HRT Oestrogens (P19) ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

Print - Print page.