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Betablockers (P1)

S Jill Stocks, Evangelos Kontopantelis, Artur Akbarov, Sarah Rodgers, Anthony J Avery, Darren M Aschroft

Type
Drug
ID
PH681
Version ID
1362
Data Sources
Valid event data range
Start - 01/02/2013
Sex
Female, Male
Agreement Date
2015-11-03
Coding system
GPRD product codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Study question:

What is the prevalence of different types of potentially hazardous prescribing in general practice in the United Kingdom, and what is the variation between practices?

Methods:

A cross sectional study included all adult patients potentially at risk of a prescribing or monitoring error defined by a combination of diagnoses and prescriptions in 526 general practices contributing to the Clinical Practice Research Datalink (CPRD) up to 1 April 2013. Primary outcomes were the prevalence of potentially hazardous prescriptions of anticoagulants, anti-platelets, NSAIDs, β blockers, glitazones, metformin, digoxin, antipsychotics, combined hormonal contraceptives, and oestrogens and monitoring by blood test less frequently than recommended for patients with repeated prescriptions of angiotensin converting enzyme inhibitors and loop diuretics, amiodarone, methotrexate, lithium, or warfarin.

Study answer and limitations:

49 927 of 949 552 patients at risk triggered at least one prescribing indicator (5.26%, 95% confidence interval 5.21% to 5.30%) and 21 501 of 182 721 (11.8%, 11.6% to 11.9%) triggered at least one monitoring indicator. The prevalence of different types of potentially hazardous prescribing ranged from almost zero to 10.2%, and for inadequate monitoring ranged from 10.4% to 41.9%. Older patients and those prescribed multiple repeat medications had significantly higher risks of triggering a prescribing indicator whereas younger patients with fewer repeat prescriptions had significantly higher risk of triggering a monitoring indicator. There was high variation between practices for some indicators. Though prescribing safety indicators describe prescribing patterns that can increase the risk of harm to the patient and should generally be avoided, there will always be exceptions where the indicator is clinically justified. Furthermore there is the possibility that some information is not captured by CPRD for some practices—for example, INR results in patients receiving warfarin.

What this study adds:

The high prevalence for certain indicators emphasises existing prescribing risks and the need for their appropriate consideration within primary care, particularly for older patients and those taking multiple medications. The high variation between practices indicates potential for improvement through targeted practice level intervention.

Publications

  • S Jill Stocks, Evangelos Kontopantelis, Artur Akbarov, Sarah Rodgers, Anthony J Avery, Darren M Ashcroft, Examining variations in prescribing safety in UK general practice cross sectional study using the Clinical Practice Research Datalink. BMJ, 351(h5501), 2015.

Clinical Code List

Rows: 554
Code Description Coding System (CPRD_product_code) Entity type Category
1006 Half Inderal LA 80mg capsules (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
10191 Atenix 50 tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
10429 Lopresor 50mg Tablet (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
1048 Inderal 80mg tablets (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
1050 Inderal 40mg tablets (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
10627 Co-Betaloc tablets (Pfizer Ltd) CPRD_product_code res25: P1betablockers drug
10716 Corgard 80mg tablets (Sanofi) CPRD_product_code res25: P1betablockers drug
10777 Trasicor 160mg Tablet (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
10892 Emcor 10mg tablets (Merck Serono Ltd) CPRD_product_code res25: P1betablockers drug
1124 Tenoretic 100mg/25mg tablets (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
11338 Bendroflumethiazide 5mg with Nadolol 40mg tablets CPRD_product_code res25: P1betablockers drug
11380 Sotacor 160mg tablets (Bristol-Myers Squibb Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
11432 TIMOPTOL preservative free unit dose eye drops 0.5% [M S D] CPRD_product_code res25: P1betablockers drug
11454 timolol maleate gel-forming eye drops 0.5% CPRD_product_code res25: P1betablockers drug
11711 Propranolol 50mg/5ml oral solution CPRD_product_code res25: P1betablockers drug
11793 Metoprolol 50mg/5ml oral suspension CPRD_product_code res25: P1betablockers drug
12037 Betim 10mg Tablet (ICN Pharmaceuticals France S.A.) CPRD_product_code res25: P1betablockers drug
12054 Propranolol 80mg / Bendroflumethiazide 2.5mg capsules CPRD_product_code res25: P1betablockers drug
12141 Betaxolol 20mg tablets CPRD_product_code res25: P1betablockers drug
12191 GLAULINE eye drops 0.6% [S & N] CPRD_product_code res25: P1betablockers drug
12296 Sectral 100mg capsules (Sanofi) CPRD_product_code res25: P1betablockers drug
12456 Sotazide Tablet (Bristol-Myers Squibb Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
12495 Berkolol 10mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
12517 Timolol maleate with bendroflumethiazide 20mg + 5mg Tablet CPRD_product_code res25: P1betablockers drug
12519 Kerlone 20mg tablets (Sanofi-Synthelabo Ltd) CPRD_product_code res25: P1betablockers drug
12651 Timolol 10mg / Bendroflumethiazide 2.5mg tablets CPRD_product_code res25: P1betablockers drug
12678 BETOPTIC ophthalmic suspension 0.25% [ALCON] CPRD_product_code res25: P1betablockers drug
12749 metipranolol preservative free eye drops 0.1% CPRD_product_code res25: P1betablockers drug
1288 Tenoret 50mg/12.5mg tablets (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
1290 Bisoprolol 10mg tablets CPRD_product_code res25: P1betablockers drug
1295 Labetalol 400mg tablets CPRD_product_code res25: P1betablockers drug
13051 Sotalol 200mg tablets CPRD_product_code res25: P1betablockers drug
1333 Oxprenolol 40mg tablets CPRD_product_code res25: P1betablockers drug
1334 Oxprenolol 160mg modified-release tablets CPRD_product_code res25: P1betablockers drug
13394 Tenormin 25mg/5ml syrup (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
13487 Beta-Cardone 200mg tablets (Focus Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
13499 Lopresor 100mg Tablet (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
13526 Atenix Co 100 tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
13871 Co-prenozide 160mg/0.25mg modified-release tablets CPRD_product_code res25: P1betablockers drug
14030 Cardicor 2.5mg tablets (Merck Serono Ltd) CPRD_product_code res25: P1betablockers drug
14057 Pindolol 10mg / Clopamide 5mg tablets CPRD_product_code res25: P1betablockers drug
14058 Cardicor 1.25mg tablets (Merck Serono Ltd) CPRD_product_code res25: P1betablockers drug
14117 Eucardic 3.125mg tablets (Roche Products Ltd) CPRD_product_code res25: P1betablockers drug
14126 Acebutolol 200mg / Hydrochlorothiazide 12.5mg tablets CPRD_product_code res25: P1betablockers drug
14146 Eucardic 6.25mg tablets (Roche Products Ltd) CPRD_product_code res25: P1betablockers drug
14211 MINIMS METIPRANOLOL eye drops 0.1% [BAUSCH & L] CPRD_product_code res25: P1betablockers drug
14286 timolol with travoprost eye drops 0.5% + 0.004% CPRD_product_code res25: P1betablockers drug
14319 DUOTRAV eye drops [ALCON] CPRD_product_code res25: P1betablockers drug
14438 Corgaretic 80mg tablets (Sanofi-Synthelabo Ltd) CPRD_product_code res25: P1betablockers drug
1448 Propranolol 160mg modified-release capsules CPRD_product_code res25: P1betablockers drug
14552 Propanix 10mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
14673 Pindolol 15mg tablets CPRD_product_code res25: P1betablockers drug
14808 Bedranol SR 80mg capsules (Sandoz Ltd) CPRD_product_code res25: P1betablockers drug
14877 NYOGEL eye gel 0.1% [ALCON] CPRD_product_code res25: P1betablockers drug
14952 COMBIGAN eye drops [ALLERGAN] CPRD_product_code res25: P1betablockers drug
15042 Tolerzide Tablet (Bristol-Myers Squibb Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
15117 Nifedipine with atenolol 20mg + 50mg Capsule CPRD_product_code res25: P1betablockers drug
15176 Totamol 50mg Tablet (C P Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
15488 Metoprolol tartrate with chlortalidone Tablet CPRD_product_code res25: P1betablockers drug
15619 Half-betadur cr 80mg Capsule (Monmouth Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
1572 Sotalol 80mg tablets CPRD_product_code res25: P1betablockers drug
15730 Totamol 100mg Tablet (C P Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
1597 Labetalol 100mg tablets CPRD_product_code res25: P1betablockers drug
16032 timolol maleate eye gel 0.1% CPRD_product_code res25: P1betablockers drug
16156 timolol with bimatoprost eye drops 0.5% + 0.03% CPRD_product_code res25: P1betablockers drug
16645 Labrocol 400mg Tablet (Lagap) CPRD_product_code res25: P1betablockers drug
16776 Celectol 400mg Tablet (Pantheon Healthcare Ltd) CPRD_product_code res25: P1betablockers drug
16786 Chlortalidone 25mg with Atenolol 100mg tablets CPRD_product_code res25: P1betablockers drug
1684 Beta-Adalat modified-release capsules (Bayer Plc) CPRD_product_code res25: P1betablockers drug
17082 Syprol 5mg/5ml oral solution (Rosemont Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
17115 timolol maleate with dorzolamide eye drops 0.5% + 2% CPRD_product_code res25: P1betablockers drug
17149 Monozide 10 tablets (Wyeth Pharmaceuticals) CPRD_product_code res25: P1betablockers drug
17322 Atenix 25 tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
17462 Bisoprolol 10mg / Hydrochlorothiazide 6.25mg tablets CPRD_product_code res25: P1betablockers drug
17615 Cardicor 5mg tablets (Merck Serono Ltd) CPRD_product_code res25: P1betablockers drug
17759 metipranolol eye drops 0.1% CPRD_product_code res25: P1betablockers drug
17783 Spiroprop Tablet (Pharmacia Ltd) CPRD_product_code res25: P1betablockers drug
1788 Atenolol 100mg with Chlortalidone 25mg tablets CPRD_product_code res25: P1betablockers drug
18114 metipranolol preservative free eye drops 0.3% CPRD_product_code res25: P1betablockers drug
18185 Cardicor 7.5mg tablets (Merck Serono Ltd) CPRD_product_code res25: P1betablockers drug
18287 Co-Betaloc SA tablets (Pfizer Ltd) CPRD_product_code res25: P1betablockers drug
18414 Eucardic 12.5mg tablets (Roche Products Ltd) CPRD_product_code res25: P1betablockers drug
18743 Tenben 25mg/1.25mg capsules (Galen Ltd) CPRD_product_code res25: P1betablockers drug
18950 Totamol 25mg Tablet (C P Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
18956 MINIMS METIPRANOLOL eye drops 0.6% [BAUSCH & L] CPRD_product_code res25: P1betablockers drug
19055 Chlortalidone 12.5mg with Atenolol 50mg tablets CPRD_product_code res25: P1betablockers drug
1910 levobunolol eye drops 0.5% CPRD_product_code res25: P1betablockers drug
19142 Bendroflumethiazide 2.5mg with Timolol maleate 10mg tablets CPRD_product_code res25: P1betablockers drug
19149 betaxolol hydrochloride preservative free ophthalmic suspension 0.25% CPRD_product_code res25: P1betablockers drug
19172 Atenolol 25mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
19178 Bisoprolol 10mg tablets (Ranbaxy (UK) Ltd) CPRD_product_code res25: P1betablockers drug
19182 Atenolol 50mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
19191 Atenolol 100mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
19200 Bisoprolol 5mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
19202 Carvedilol 6.25mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
19437 Eucardic 25mg tablets (Roche Products Ltd) CPRD_product_code res25: P1betablockers drug
197 Atenolol 5mg/10ml solution for injection ampoules CPRD_product_code res25: P1betablockers drug
19853 Cardicor 3.75mg tablets (Merck Serono Ltd) CPRD_product_code res25: P1betablockers drug
19858 Cardicor 10mg tablets (Merck Serono Ltd) CPRD_product_code res25: P1betablockers drug
20012 Visken 15mg Tablet (Sovereign Medical Ltd) CPRD_product_code res25: P1betablockers drug
20015 MINIMS METIPRANOLOL eye drops 0.3% [BAUSCH & L] CPRD_product_code res25: P1betablockers drug
20082 Lopresor SR 200mg tablets (Recordati Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
20093 Metoprolol 200mg modified-release / Hydrochlorothiazide 25mg tablets CPRD_product_code res25: P1betablockers drug
20363 GANFORT eye drops [ALLERGAN] CPRD_product_code res25: P1betablockers drug
20468 Half Beta-Prograne 80mg modified-release capsules (Tillomed Laboratories Ltd) CPRD_product_code res25: P1betablockers drug
20502 Atenix 100 tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
20728 Atenamin 25mg Tablet (OPD Pharm) CPRD_product_code res25: P1betablockers drug
21025 Prestim forte Tablet (LEO Pharma) CPRD_product_code res25: P1betablockers drug
21133 Atenamin 50mg Tablet (OPD Pharm) CPRD_product_code res25: P1betablockers drug
21182 Hydrochlorothiazide with timolol and amiloride 25mg with 10mg with 2.5mg Tablet CPRD_product_code res25: P1betablockers drug
21506 GLAU-OPT eye drops 0.25% [OPUS] CPRD_product_code res25: P1betablockers drug
21508 GLAU-OPT eye drops 0.5% [OPUS] CPRD_product_code res25: P1betablockers drug
21706 BETOPTIC preservative free ophthalmic suspension 0.25% [ALCON] CPRD_product_code res25: P1betablockers drug
21838 Propanix 80mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
21839 Berkolol 80mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
21866 Berkolol 40mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
21873 Atenix Co 50 tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
21885 Oxyprenix SR 160mg tablets CPRD_product_code res25: P1betablockers drug
21905 Bipranix 10mg tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
21966 Bipranix 5mg tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
220 Propranolol 5mg/5ml oral solution CPRD_product_code res25: P1betablockers drug
22208 Half propanix la 80mg Modified-release capsule (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
22793 Labrocol 200mg Tablet (Lagap) CPRD_product_code res25: P1betablockers drug
22912 Bendroflumethiazide 2.5mg with Propanolol 80mg capsules CPRD_product_code res25: P1betablockers drug
23131 Bendroflumethiazide 5mg with Propanolol 160mg modified-release capsules CPRD_product_code res25: P1betablockers drug
23134 Nadolol 40mg / Bendroflumethiazide 5mg tablets CPRD_product_code res25: P1betablockers drug
23326 Betadur cr 160mg Modified-release capsule (Monmouth Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
23587 Sloprolol 160mg Capsule (C P Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
2361 Trasicor 80mg Tablet (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
2378 TIMOPTOL eye drops 0.5% [M S D] CPRD_product_code res25: P1betablockers drug
2380 GLAUCOL unit dose eye drops 0.5% [IVAX] CPRD_product_code res25: P1betablockers drug
2381 timolol maleate preservative free unit dose eye drops 0.5% CPRD_product_code res25: P1betablockers drug
24 Atenolol 100mg tablets CPRD_product_code res25: P1betablockers drug
24083 Bisoprolol 5mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
24094 Trasicor 40mg tablets (Amdipharm Plc) CPRD_product_code res25: P1betablockers drug
2414 Inderal 10mg tablets (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
24191 Antipressan 50mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
24195 Antipressan 100mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
24218 Berkolol 160mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
24280 Totaretic 100mg+25mg Tablet (C P Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
2432 Tenormin LS 50mg tablets (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
24832 Lasipressin Tablet (Hoechst UK Ltd) CPRD_product_code res25: P1betablockers drug
2499 Nadolol 80mg tablets CPRD_product_code res25: P1betablockers drug
2523 BETOPTIC eye drops 0.5% [ALCON] CPRD_product_code res25: P1betablockers drug
25359 Rapranol SR 160mg capsules (Ranbaxy (UK) Ltd) CPRD_product_code res25: P1betablockers drug
25363 Prestim tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
25367 Rapranol SR 80mg capsules (Ranbaxy (UK) Ltd) CPRD_product_code res25: P1betablockers drug
25462 Clopamide 5mg with Pindolol 10mg tablets CPRD_product_code res25: P1betablockers drug
25644 Apsolox 80mg Tablet (Approved Prescription Services Ltd) CPRD_product_code res25: P1betablockers drug
25730 Timolol maleate with amiloride and hydrochlorothiazide Tablet CPRD_product_code res25: P1betablockers drug
2587 Tenormin 100mg tablets (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
2590 Tenormin 25mg tablets (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
26 Atenolol 25mg tablets CPRD_product_code res25: P1betablockers drug
26211 Antipressan 25mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
26228 Propanix LA 160mg Modified-release capsule (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
26229 Beta-Prograne 160mg modified-release capsules (Tillomed Laboratories Ltd) CPRD_product_code res25: P1betablockers drug
26248 Tenchlor 100mg/25mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
26255 Lopranol la 160mg Capsule (Opus Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
2629 Carvedilol 12.5mg tablets CPRD_product_code res25: P1betablockers drug
26529 Furosemide with penbutolol Tablet CPRD_product_code res25: P1betablockers drug
26741 Totaretic 50mg+12.5mg Tablet (C P Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
26895 Syprol 10mg/5ml oral solution (Rosemont Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
27141 COSOPT preservative free eye drops [M S D] CPRD_product_code res25: P1betablockers drug
27357 Oxprenolol 40mg Tablet (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
27700 Propranolol 40mg tablets (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
27719 Metoros ls 95mg Tablet (Geigy Pharmaceuticals) CPRD_product_code res25: P1betablockers drug
2774 GLAUCOL unit dose eye drops 0.25% [IVAX] CPRD_product_code res25: P1betablockers drug
2775 Labetalol 200mg tablets CPRD_product_code res25: P1betablockers drug
2780 Oxprenolol 80mg tablets CPRD_product_code res25: P1betablockers drug
27946 Nadolol 80mg / Bendroflumethiazide 5mg tablets CPRD_product_code res25: P1betablockers drug
27964 Apsolol 40mg Tablet (Approved Prescription Services Ltd) CPRD_product_code res25: P1betablockers drug
28048 Angilol 10mg Tablet (DDSA Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
28128 Propranolol 80mg Modified-release capsule (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
28177 Hydrochlorothiazide with atenolol and amiloride Capsule CPRD_product_code res25: P1betablockers drug
28700 Cartrol 10mg Tablet (Novartis Consumer Health UK Ltd) CPRD_product_code res25: P1betablockers drug
28788 Half propatard la 80mg Modified-release capsule (Galen Ltd) CPRD_product_code res25: P1betablockers drug
28996 Bedranol SR 160mg capsules (Sandoz Ltd) CPRD_product_code res25: P1betablockers drug
29180 Trasicor 80mg tablets (Amdipharm Plc) CPRD_product_code res25: P1betablockers drug
29230 Slow-pren 160mg Tablet (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
29368 Atenolol 25mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
29398 Atenamin 100mg Tablet (OPD Pharm) CPRD_product_code res25: P1betablockers drug
29427 Hydrochlorothiazide with metoprolol tartrate 12.5mg with 100mg tablet CPRD_product_code res25: P1betablockers drug
29610 Betim 10mg tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
297 Propranolol 10mg tablets CPRD_product_code res25: P1betablockers drug
29762 Mepranix 50mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
29763 Propanix 160mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
29827 Carteolol HCl 10mg tablets CPRD_product_code res25: P1betablockers drug
29998 Metoros 190mg Tablet (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
3005 Inderal LA 160mg capsules (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
30400 Mepranix 100mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
30519 Amiloride with timolol with hydrochlorothiazide tablets CPRD_product_code res25: P1betablockers drug
30636 Vasaten 50mg Tablet (Shire Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
30770 Labetalol 200mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
3084 betaxolol hydrochloride eye drops 0.5% CPRD_product_code res25: P1betablockers drug
3085 carteolol hydrochloride eye drops 1% CPRD_product_code res25: P1betablockers drug
3087 Propranolol 40mg/5ml oral solution sugar free CPRD_product_code res25: P1betablockers drug
3112 TEOPTIC eye drops 1% [SPECTRUM] CPRD_product_code res25: P1betablockers drug
31214 Propranolol 80mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
313 TIMOPTOL eye drops 0.25% [M S D] CPRD_product_code res25: P1betablockers drug
31470 Tenchlor 50mg/12.5mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
31536 Atenolol 25mg tablets (Kent Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
3167 Propranolol 160mg tablets CPRD_product_code res25: P1betablockers drug
31708 Co-tenidone 50mg/12.5mg tablets (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
31776 Propranolol 40mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
31833 Angilol 80mg Tablet (DDSA Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
31934 Atenolol 100mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
32094 Co-tenidone 50mg/12.5mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
32114 Bisoprolol 5mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
32162 Propranolol 80mg Modified-release capsule (Lagap) CPRD_product_code res25: P1betablockers drug
32552 Congescor 2.5mg tablets (Tillomed Laboratories Ltd) CPRD_product_code res25: P1betablockers drug
32630 Vivacor 10mg tablets (Lexon (UK) Ltd) CPRD_product_code res25: P1betablockers drug
32634 TIMOLOL eye drops 0.25% [TEVA] CPRD_product_code res25: P1betablockers drug
32787 Visken 15mg tablets (AMCo) CPRD_product_code res25: P1betablockers drug
32836 Metoprolol 50mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
33079 Atenolol 100mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
33085 Atenolol 100mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
33092 Atenolol 50mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
33184 Atenolol 100mg tablets (Wockhardt UK Ltd) CPRD_product_code res25: P1betablockers drug
33374 Carvedilol 12.5mg tablets (Genus Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
33376 Probeta LA 160mg Capsule (Trinity Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
33403 TIMOLOL eye drops 0.25% [LENNON] CPRD_product_code res25: P1betablockers drug
3344 Betaloc 100mg tablets (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
33569 Oxprenolol sr 160mg Modified-release tablet (Hillcross Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
33602 Slo-Pro 160mg capsules (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
33644 Propranolol 80mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
33650 Atenolol 50mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
33657 Atenolol 25mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
33659 Hydrochlorothiazide with metoprolol tartrate 25mg with 200mg Modified-release tablet CPRD_product_code res25: P1betablockers drug
33836 Apsolol 160mg Tablet (Approved Prescription Services Ltd) CPRD_product_code res25: P1betablockers drug
33839 Bisoprolol 10mg tablets (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
33850 Atenolol 50mg tablets (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
33909 Congescor 1.25mg tablets (Tillomed Laboratories Ltd) CPRD_product_code res25: P1betablockers drug
34012 Co-tenidone 100mg/25mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
34034 Co-tenidone 50mg/12.5mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
34092 Metoprolol 100mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
34094 Metoprolol 50mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
34125 Metoprolol 100mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
34153 TIMOLOL eye drops 0.25% [GEN (UK)] CPRD_product_code res25: P1betablockers drug
34171 Labetalol 100mg Tablet (C P Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
34177 Labetalol 100mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
34185 Propranolol LA 80mg Modified-release capsule (Approved Prescription Services Ltd) CPRD_product_code res25: P1betablockers drug
34188 Labetalol 200mg Tablet (Celltech Pharma Europe Ltd) CPRD_product_code res25: P1betablockers drug
34208 Propranolol SR 160mg Modified-release capsule (C P Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
34214 Propranolol 160mg tablets (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
34227 TIMOLOL eye drops 0.5% [LENNON] CPRD_product_code res25: P1betablockers drug
34265 Atenolol 50mg tablets (Sandoz Ltd) CPRD_product_code res25: P1betablockers drug
34337 TIMOLOL eye drops 0.25% [ACTAVIS] CPRD_product_code res25: P1betablockers drug
34365 Atenolol 50mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
34371 Sotalol 40mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
34378 Propranolol 10mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
34407 Metoprolol 50mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
34430 Metoprolol 50mg tablets (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
34443 Atenolol 50mg tablets (Wockhardt UK Ltd) CPRD_product_code res25: P1betablockers drug
34449 Co-tenidone 50mg/12.5mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
34492 Atenolol 25mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
34501 Carvedilol 12.5mg tablets (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
34509 Metoprolol 100mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
34520 Sotalol 80mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
34575 Atenolol 25mg tablets (Wockhardt UK Ltd) CPRD_product_code res25: P1betablockers drug
34584 Metoprolol 50mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
34585 Atenolol 25mg tablets (Sandoz Ltd) CPRD_product_code res25: P1betablockers drug
34600 Sotalol 40mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
34640 Sotalol 40mg Tablet (Tillomed Laboratories Ltd) CPRD_product_code res25: P1betablockers drug
34690 Sotalol 80mg tablets (Sandoz Ltd) CPRD_product_code res25: P1betablockers drug
34695 Atenolol 50mg tablets (Kent Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
3474 Betaloc-SA 200mg tablets (AstraZeneca UK Ltd) CPRD_product_code res25: P1betablockers drug
34740 Carvedilol 6.25mg tablets (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
34741 Carvedilol 3.125mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
34754 Atenolol 100mg tablets (Sandoz Ltd) CPRD_product_code res25: P1betablockers drug
34783 Propranolol 10mg tablets (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
34785 TIMOLOL eye drops 0.5% [GEN (UK)] CPRD_product_code res25: P1betablockers drug
34804 Propranolol 10mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
34818 TIMOLOL eye drops 0.25% [IVAX] CPRD_product_code res25: P1betablockers drug
34821 Bisoprolol 10mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
34825 Co-tenidone 50mg/12.5mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
34854 Metoprolol 100mg tablets (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
34867 Propranolol 80mg Capsule (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
34868 Propranolol 40mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
34882 Atenolol 50mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
34884 Propranolol 160mg Modified-release capsule (Sandoz Ltd) CPRD_product_code res25: P1betablockers drug
34890 Metoprolol 50mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
34899 Co-tenidone 100mg/25mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
34925 Metoprolol 50mg tablets (Sandoz Ltd) CPRD_product_code res25: P1betablockers drug
34945 Propranolol 160mg Modified-release capsule (Lagap) CPRD_product_code res25: P1betablockers drug
34949 Propranolol 160mg Modified-release capsule (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
3495 GLAULINE eye drops 0.1% [S & N] CPRD_product_code res25: P1betablockers drug
34963 Bisoprolol 5mg tablets (Actavis UK Ltd) CPRD_product_code res25: P1betablockers drug
34976 Atenolol 25mg tablets (Tillomed Laboratories Ltd) CPRD_product_code res25: P1betablockers drug
35054 Celectol 200mg tablets (Zentiva) CPRD_product_code res25: P1betablockers drug
35062 Trasicor 20mg tablets (Amdipharm Plc) CPRD_product_code res25: P1betablockers drug
3516 Oxprenolol 20mg tablets CPRD_product_code res25: P1betablockers drug
35256 dorzolamide hydrochloride with timolol maleate preservative free eye drops 2% + 0.5% CPRD_product_code res25: P1betablockers drug
3526 Amiloride with atenolol with hydrochlorothiazide capsules CPRD_product_code res25: P1betablockers drug
35695 Visken 5mg tablets (AMCo) CPRD_product_code res25: P1betablockers drug
35710 Sotalol 25mg/5ml oral suspension CPRD_product_code res25: P1betablockers drug
35778 Labrocol 100mg Tablet (Lagap) CPRD_product_code res25: P1betablockers drug
3588 Monocor 5mg tablets (Wyeth Pharmaceuticals) CPRD_product_code res25: P1betablockers drug
35933 LEVOBUNOLOL eye drops 0.5% [CUSI] CPRD_product_code res25: P1betablockers drug
35938 Propranolol 80mg modified-release capsules (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
35940 Celectol 400mg tablets (Zentiva) CPRD_product_code res25: P1betablockers drug
36261 Atenolol 50mg tablets (Tillomed Laboratories Ltd) CPRD_product_code res25: P1betablockers drug
36576 Propranolol 10mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
36603 Propranolol SR 160mg Modified-release capsule (Hillcross Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
367 BETAGAN eye drops 0.5% [ALLERGAN] CPRD_product_code res25: P1betablockers drug
3691 Sotalol 160mg with hydrochlorothiazide 25mg tablet CPRD_product_code res25: P1betablockers drug
37118 Bisoprolol 2.5mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
3748 Oxprenolol 160mg Tablet CPRD_product_code res25: P1betablockers drug
3765 BETAGAN preservative free eye drops 0.5% [ALLERGAN] CPRD_product_code res25: P1betablockers drug
37725 Co-tenidone 100mg/25mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
37837 Bisoprolol 2.5mg Tablet (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
3827 Propanix 40mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
38433 Propranolol 50mg/5ml Oral solution (Rosemont Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
38991 Bisoprolol 7.5mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
39233 Propranolol 80mg modified-release capsules (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
39423 Sotalol 80mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
39646 Bisoprolol 0.625mg/5ml oral solution CPRD_product_code res25: P1betablockers drug
3971 TEOPTIC eye drops 2% w/v [SPECTRUM] CPRD_product_code res25: P1betablockers drug
39846 Vivacor 5mg tablets (Lexon (UK) Ltd) CPRD_product_code res25: P1betablockers drug
4004 Sotacor 80mg tablets (Bristol-Myers Squibb Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
40167 Metoprolol 100mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: P1betablockers drug
40240 Labetalol 400mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
40241 Propranolol LA 160mg Capsule (Approved Prescription Services Ltd) CPRD_product_code res25: P1betablockers drug
40242 TIMOLOL eye drops 0.5% [TEVA] CPRD_product_code res25: P1betablockers drug
4025 Slow-Trasicor 160mg tablets (AMCo) CPRD_product_code res25: P1betablockers drug
40257 AZARGA eye drops 10mg + 5mg/ml [ALCON] CPRD_product_code res25: P1betablockers drug
40289 brinzolamide with timolol eye drops 10mg + 5mg/ml CPRD_product_code res25: P1betablockers drug
4059 betaxolol hydrochloride ophthalmic suspension 0.25% CPRD_product_code res25: P1betablockers drug
40761 Nebivolol 2.5mg tablets CPRD_product_code res25: P1betablockers drug
41555 Propranolol 40mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
41572 Co-tenidone 100mg/25mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
41591 Bisoprolol 10mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
41740 Celiprolol 200mg tablets (Teva UK Ltd) CPRD_product_code res25: P1betablockers drug
41827 Labetalol 100mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
42152 Syprol 50mg/5ml oral solution (Rosemont Pharmaceuticals Ltd) CPRD_product_code res25: P1betablockers drug
4265 Celectol 200mg Tablet (Pantheon Healthcare Ltd) CPRD_product_code res25: P1betablockers drug
42795 Celiprolol 200mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
42796 TIMOLOL eye drops 0.5% [ACTAVIS] CPRD_product_code res25: P1betablockers drug
43251 Bisoprolol 1.25mg tablets (Generics (UK) Ltd) CPRD_product_code res25: P1betablockers drug
43427 TIMOLOL eye drops 0.25% [HILLCROSS] CPRD_product_code res25: P1betablockers