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Psoriasis

Rosa Parisi, Martin K Rutter, Mark Lunt, Helen S Young, Deborah P M Symmons, Christopher E M Griffiths, Darren M Ashcroft

Type
Disease or Syndrome
ID
PH7
Version ID
14
Valid event data range
01/01/1994 - 31/12/2009
Sex
Female, Male
Agreement Date
2015-04-09
Coding system
Read codes v2
Tags /Collections
Phenotype Library

Definition

The study population included patients with a first diagnosis of psoriasis between 1 January 1994 and 31 December 2009, who were 20 years or older at the time of the diagnosis. A comparison group of up to 5 controls per psoriasis patient was selected. Patients from both cohorts did not have any history of CVD or diabetes before the index date (first diagnosis of psoriasis) or corresponding consulting date and, in order to capture incident not prevalent cases of psoriasis or major CV events, all patients had to have at least 2 years prior registration within their general practice before entry into the study cohort. The control group consisted of patients who never received a diagnostic code for psoriasis. Controls were matched to psoriasis patients by age, gender, and general practice. We assigned control patients the same index date as the patients with psoriasis to whom they were matched. Person-time under observation for each patient was calculated from the corresponding index date up to the end of the study, which was the earliest date of the occurrence of a major CV event (MI, ACS, unstable angina, or stroke), transfer out of the practice, death date, end of follow-up (31 December 2011) or when the practice was no longer up to research data quality standards set by CPRD. Patient consent was not required; all patient data contained in CPRD is anonymised.

Patients with psoriasis were included if they had their first diagnostic code for psoriasis during 1 January 1994–31 December 2009 and received a recognized treatment for psoriasis (emollients, topical treatment, phototherapy, systemic therapy, or biologics (CG153 Psoriasis: NICE guideline; Samarasekera and Smith, 2014)). Patients were classified as having severe psoriasis once they had received a systemic treatment (acitretin, etretinate, ciclosporin, hydroxycarbamide, methotrexate, and fumaric acid), phototherapy, or a biologic therapy (etanercept, adalimumab, infliximab, ustekinumab, and efalizumab); alternatively they were classified as mild psoriasis.

Implementation


Publications

  • Rosa Parisi, Martin K Rutter, Mark Lunt, Helen S. Young, Deborah P M Symmons, Christopher E M Griffiths, Darren M. Ashcroft, "Psoriasis and the Risk of Major Cardiovascular Events: Cohort Study Using the Clinical Practice Research Datalink". Journal of Investigative Dermatology, 135(9), 2189-2197, 2015.

Clinical Code List

Rows: 24
Code Description coding_system upload_date entity list_name
M16..00 Psoriasis and similar disorders Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161.00 Other psoriasis Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161000 Psoriasis unspecified Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161100 Psoriasis annularis Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161200 Psoriasis circinata Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161300 Psoriasis diffusa Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161400 Psoriasis discoidea Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161500 Psoriasis geographica Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161600 Guttate psoriasis Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161700 Psoriasis gyrata Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161800 Psoriasis inveterata Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161900 Psoriasis ostracea Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161A00 Psoriasis palmaris Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161B00 Psoriasis plantaris Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161C00 Psoriasis punctata Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161E00 Psoriasis universalis Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161F00 Psoriasis vulgaris Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161F11 Chronic large plaque psoriasis Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161H00 Erythrodermic psoriasis Read 2018-04-17 diagnostic 696 - res66: psoriasis
M161z00 Psoriasis NOS Read 2018-04-17 diagnostic 696 - res66: psoriasis
M16y.00 Other psoriasis and similar disorders Read 2018-04-17 diagnostic 696 - res66: psoriasis
M16y000 Scalp psoriasis Read 2018-04-17 diagnostic 696 - res66: psoriasis
M16z.00 Psoriasis and similar disorders NOS Read 2018-04-17 diagnostic 696 - res66: psoriasis
Myu3000 [X]Other psoriasis Read 2018-04-17 diagnostic 696 - res66: psoriasis

Version History

Version
ID
Name Owner Publish date
14 Psoriasis ieuan.scanlon 2021-10-06 currently shown

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