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Depression

K Windfuhr, D While, N Kapur, D M Ashcroft, E Kontopantelis, M J Carr, J Shaw, L Applyby, R T Webb

Type
Disease or Syndrome
ID
PH700
Version ID
1400
Data Sources
Valid event data range
01/01/2002 - 31/12/2011
Sex
Female, Male
Agreement Date
2016-09-21
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Background:

Little is known about the precursors of suicide risk among primary-care patients. This study aimed to examine suicide risk in relation to patterns of clinical consultation, psychotropic drug prescribing, and psychiatric diagnoses.

Method:

Nested case-control study in the Clinical Practice Research Datalink (CPRD), England. Patients aged516 years who died by suicide during 2002–2011 (N = 2384) were matched on gender, age and practice with up to 20 living control patients (N = 46 899).

Results:

Risk was raised among non-consulting patients, and increased sharply with rising number of consultations in the preceding year [512 consultations v. 1: unadjusted odds ratio (OR) 6.0, 95% confidence interval (CI) 4.9–7.3]. Markedly elevated risk was also associated with the prescribing of multiple psychotropic medication types (55 types v. 0: OR 62.6, CI 44.3–88.4) and with having several psychiatric diagnoses (54 diagnoses v. 0: OR 31.1, CI 19.3–50.1). Risk was also raised among patients living in more socially deprived localities. The confounding effect of multiple psychotropic drug types largely accounted for the rising risk gradient observed with increasing consultation frequency.

Conclusions:

A greater proportion of patients with several psychiatric diagnoses, those prescribed multiple psychotropic medication types, and those who consult at very high frequency might be considered for referral to mental health services by their general practitioners. Non-consulters are also at increased risk, which suggests that conventional models of primary care may not be effective in meeting the needs of all people in the community experiencing major psychosocial difficulties.

Publications

  • K Windfuhr, D While, N Kapur, D M Ashcroft, E Kontopantelis, M J Carr, J Shaw, L Appleby, R T Webb, Suicide risk linked with clinical consultation frequency, psychiatric diagnoses and psychotropic medication prescribing in a national study of primary-care patients. Psychological Medicine, 46, 3407-3417, 2016.

Clinical Code List

Rows: 105
Code Description Entity type Category Coding System (Read)
1B17.00 Depressed res38: Depression diagnostic Read
2257.00 O/E - depressed res38: Depression diagnostic Read
62T1.00 Puerperal depression res38: Depression diagnostic Read
9kQ..00 On full dose long term treatment depression - enh serv admin res38: Depression diagnostic Read
E001300 Presenile dementia with depression res38: Depression diagnostic Read
E002100 Senile dementia with depression res38: Depression diagnostic Read
E004300 Arteriosclerotic dementia with depression res38: Depression diagnostic Read
E11..12 Depressive psychoses res38: Depression diagnostic Read
E112.00 Single major depressive episode res38: Depression diagnostic Read
E112.11 Agitated depression res38: Depression diagnostic Read
E112.12 Endogenous depression first episode res38: Depression diagnostic Read
E112.13 Endogenous depression first episode res38: Depression diagnostic Read
E112.14 Endogenous depression res38: Depression diagnostic Read
E112000 Single major depressive episode, unspecified res38: Depression diagnostic Read
E112100 Single major depressive episode, mild res38: Depression diagnostic Read
E112200 Single major depressive episode, moderate res38: Depression diagnostic Read
E112300 Single major depressive episode, severe, without psychosis res38: Depression diagnostic Read
E112400 Single major depressive episode, severe, with psychosis res38: Depression diagnostic Read
E112z00 Single major depressive episode NOS res38: Depression diagnostic Read
E113.00 Recurrent major depressive episode res38: Depression diagnostic Read
E113.11 Endogenous depression - recurrent res38: Depression diagnostic Read
E113000 Recurrent major depressive episodes, unspecified res38: Depression diagnostic Read
E113100 Recurrent major depressive episodes, mild res38: Depression diagnostic Read
E113200 Recurrent major depressive episodes, moderate res38: Depression diagnostic Read
E113300 Recurrent major depressive episodes, severe, no psychosis res38: Depression diagnostic Read
E113400 Recurrent major depressive episodes, severe, with psychosis res38: Depression diagnostic Read
E113700 Recurrent depression res38: Depression diagnostic Read
E113z00 Recurrent major depressive episode NOS res38: Depression diagnostic Read
E118.00 Seasonal affective disorder res38: Depression diagnostic Read
E11y200 Atypical depressive disorder res38: Depression diagnostic Read
E11z200 Masked depression res38: Depression diagnostic Read
E135.00 Agitated depression res38: Depression diagnostic Read
E200300 Anxiety with depression res38: Depression diagnostic Read
E204.00 Neurotic depression reactive type res38: Depression diagnostic Read
E204.11 Postnatal depression res38: Depression diagnostic Read
E290.00 Brief depressive reaction res38: Depression diagnostic Read
E290z00 Brief depressive reaction NOS res38: Depression diagnostic Read
E291.00 Prolonged depressive reaction res38: Depression diagnostic Read
E2B..00 Depressive disorder NEC res38: Depression diagnostic Read
E2B0.00 Postviral depression res38: Depression diagnostic Read
E2B1.00 Chronic depression res38: Depression diagnostic Read
Eu20400 [X]Post-schizophrenic depression res38: Depression diagnostic Read
Eu32.00 [X]Depressive episode res38: Depression diagnostic Read
Eu32.11 [X]Single episode of depressive reaction res38: Depression diagnostic Read
Eu32.12 [X]Single episode of psychogenic depression res38: Depression diagnostic Read
Eu32.13 [X]Single episode of reactive depression res38: Depression diagnostic Read
Eu32000 [X]Mild depressive episode res38: Depression diagnostic Read
Eu32100 [X]Moderate depressive episode res38: Depression diagnostic Read
Eu32200 [X]Severe depressive episode without psychotic symptoms res38: Depression diagnostic Read
Eu32211 [X]Single episode agitated depressn w'out psychotic symptoms res38: Depression diagnostic Read
Eu32212 [X]Single episode major depression w'out psychotic symptoms res38: Depression diagnostic Read
Eu32213 [X]Single episode vital depression w'out psychotic symptoms res38: Depression diagnostic Read
Eu32300 [X]Severe depressive episode with psychotic symptoms res38: Depression diagnostic Read
Eu32311 [X]Single episode of major depression and psychotic symptoms res38: Depression diagnostic Read
Eu32312 [X]Single episode of psychogenic depressive psychosis res38: Depression diagnostic Read
Eu32313 [X]Single episode of psychotic depression res38: Depression diagnostic Read
Eu32314 [X]Single episode of reactive depressive psychosis res38: Depression diagnostic Read
Eu32400 [X]Mild depression res38: Depression diagnostic Read
Eu32500 [X]Major depression, mild res38: Depression diagnostic Read
Eu32600 [X]Major depression, moderately severe res38: Depression diagnostic Read
Eu32700 [X]Major depression, severe without psychotic symptoms res38: Depression diagnostic Read
Eu32800 [X]Major depression, severe with psychotic symptoms res38: Depression diagnostic Read
Eu32900 [X]Single major depr ep, severe with psych, psych in remiss res38: Depression diagnostic Read
Eu32A00 [X]Recurr major depr ep, severe with psych, psych in remiss res38: Depression diagnostic Read
Eu32y00 [X]Other depressive episodes res38: Depression diagnostic Read
Eu32y11 [X]Atypical depression res38: Depression diagnostic Read
Eu32y12 [X]Single episode of masked depression NOS res38: Depression diagnostic Read
Eu32z00 [X]Depressive episode, unspecified res38: Depression diagnostic Read
Eu32z11 [X]Depression NOS res38: Depression diagnostic Read
Eu32z12 [X]Depressive disorder NOS res38: Depression diagnostic Read
Eu32z13 [X]Prolonged single episode of reactive depression res38: Depression diagnostic Read
Eu32z14 [X] Reactive depression NOS res38: Depression diagnostic Read
Eu33.00 [X]Recurrent depressive disorder res38: Depression diagnostic Read
Eu33.11 [X]Recurrent episodes of depressive reaction res38: Depression diagnostic Read
Eu33.12 [X]Recurrent episodes of psychogenic depression res38: Depression diagnostic Read
Eu33.13 [X]Recurrent episodes of reactive depression res38: Depression diagnostic Read
Eu33.14 [X]Seasonal depressive disorder res38: Depression diagnostic Read
Eu33.15 [X]SAD - Seasonal affective disorder res38: Depression diagnostic Read
Eu33000 [X]Recurrent depressive disorder, current episode mild res38: Depression diagnostic Read
Eu33100 [X]Recurrent depressive disorder, current episode moderate res38: Depression diagnostic Read
Eu33200 [X]Recurr depress disorder cur epi severe without psyc sympt res38: Depression diagnostic Read
Eu33211 [X]Endogenous depression without psychotic symptoms res38: Depression diagnostic Read
Eu33212 [X]Major depression, recurrent without psychotic symptoms res38: Depression diagnostic Read
Eu33214 [X]Vital depression, recurrent without psychotic symptoms res38: Depression diagnostic Read
Eu33300 [X]Recurrent depress disorder cur epi severe with psyc symp res38: Depression diagnostic Read
Eu33311 [X]Endogenous depression with psychotic symptoms res38: Depression diagnostic Read
Eu33312 [X]Manic-depress psychosis,depressed type+psychotic symptoms res38: Depression diagnostic Read
Eu33313 [X]Recurr severe episodes/major depression+psychotic symptom res38: Depression diagnostic Read
Eu33314 [X]Recurr severe episodes/psychogenic depressive psychosis res38: Depression diagnostic Read
Eu33315 [X]Recurrent severe episodes of psychotic depression res38: Depression diagnostic Read
Eu33316 [X]Recurrent severe episodes/reactive depressive psychosis res38: Depression diagnostic Read
Eu33400 [X]Recurrent depressive disorder, currently in remission res38: Depression diagnostic Read
Eu33y00 [X]Other recurrent depressive disorders res38: Depression diagnostic Read
Eu33z00 [X]Recurrent depressive disorder, unspecified res38: Depression diagnostic Read
Eu33z11 [X]Monopolar depression NOS res38: Depression diagnostic Read
Eu34100 [X]Dysthymia res38: Depression diagnostic Read
Eu34111 [X]Depressive neurosis res38: Depression diagnostic Read
Eu34113 [X]Neurotic depression res38: Depression diagnostic Read
Eu34114 [X]Persistant anxiety depression res38: Depression diagnostic Read
Eu3y111 [X]Recurrent brief depressive episodes res38: Depression diagnostic Read
Eu41200 [X]Mixed anxiety and depressive disorder res38: Depression diagnostic Read
Eu41211 [X]Mild anxiety depression res38: Depression diagnostic Read
Eu53011 [X]Postnatal depression NOS res38: Depression diagnostic Read
Eu53012 [X]Postpartum depression NOS res38: Depression diagnostic Read
Eu92000 [X]Depressive conduct disorder res38: Depression diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH700/version/1400/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH700/version/1400/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH700', '1400', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH700/version/1400/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH700/version/1400/export/codes/?format=json
CSV site_root/phenotypes/PH700/version/1400/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH700', '1400', api_client=client)

Version History

Version
ID
Name Owner Publish date
1400 Depression ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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