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Personality Disorder

K Windfuhr, D While, N Kapur, D M Ashcroft, E Kontopantelis, M J Carr, J Shaw, L Applyby, R T Webb

Type
Drug
ID
PH705
Version ID
1410
Data Sources
Valid event data range
01/01/2002 - 31/12/2011
Sex
Female, Male
Agreement Date
2016-09-21
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Background:

Little is known about the precursors of suicide risk among primary-care patients. This study aimed to examine suicide risk in relation to patterns of clinical consultation, psychotropic drug prescribing, and psychiatric diagnoses.

Method:

Nested case-control study in the Clinical Practice Research Datalink (CPRD), England. Patients aged516 years who died by suicide during 2002–2011 (N = 2384) were matched on gender, age and practice with up to 20 living control patients (N = 46 899).

Results:

Risk was raised among non-consulting patients, and increased sharply with rising number of consultations in the preceding year [512 consultations v. 1: unadjusted odds ratio (OR) 6.0, 95% confidence interval (CI) 4.9–7.3]. Markedly elevated risk was also associated with the prescribing of multiple psychotropic medication types (55 types v. 0: OR 62.6, CI 44.3–88.4) and with having several psychiatric diagnoses (54 diagnoses v. 0: OR 31.1, CI 19.3–50.1). Risk was also raised among patients living in more socially deprived localities. The confounding effect of multiple psychotropic drug types largely accounted for the rising risk gradient observed with increasing consultation frequency.

Conclusions:

A greater proportion of patients with several psychiatric diagnoses, those prescribed multiple psychotropic medication types, and those who consult at very high frequency might be considered for referral to mental health services by their general practitioners. Non-consulters are also at increased risk, which suggests that conventional models of primary care may not be effective in meeting the needs of all people in the community experiencing major psychosocial difficulties.

Publications

  • K Windfuhr, D While, N Kapur, D M Ashcroft, E Kontopantelis, M J Carr, J Shaw, L Appleby, R T Webb, Suicide risk linked with clinical consultation frequency, psychiatric diagnoses and psychotropic medication prescribing in a national study of primary-care patients. Psychological Medicine, 46, 3407-3417, 2016.

Clinical Code List

Rows: 78
Code Description Entity type Category Coding System (Read)
E21..00 Personality disorders res38: Personality disorder diagnostic Read
E21..11 Neurotic personality disorder res38: Personality disorder diagnostic Read
E210.00 Paranoid personality disorder res38: Personality disorder diagnostic Read
E211.00 Affective personality disorder res38: Personality disorder diagnostic Read
E211000 Unspecified affective personality disorder res38: Personality disorder diagnostic Read
E211100 Hypomanic personality disorder res38: Personality disorder diagnostic Read
E211200 Depressive personality disorder res38: Personality disorder diagnostic Read
E211300 Cyclothymic personality disorder res38: Personality disorder diagnostic Read
E211z00 Affective personality disorder NOS res38: Personality disorder diagnostic Read
E212.00 Schizoid personality disorder res38: Personality disorder diagnostic Read
E212000 Unspecified schizoid personality disorder res38: Personality disorder diagnostic Read
E212z00 Schizoid personality disorder NOS res38: Personality disorder diagnostic Read
E213.00 Explosive personality disorder res38: Personality disorder diagnostic Read
E214.00 Compulsive personality disorders res38: Personality disorder diagnostic Read
E214.11 Anancastic personality res38: Personality disorder diagnostic Read
E214000 Anankastic personality res38: Personality disorder diagnostic Read
E214z00 Compulsive personality disorder NOS res38: Personality disorder diagnostic Read
E215.00 Histrionic personality disorders res38: Personality disorder diagnostic Read
E215.11 Hysterical personality disorders res38: Personality disorder diagnostic Read
E215000 Unspecified histrionic personality disorder res38: Personality disorder diagnostic Read
E215z00 Histrionic personality disorder NOS res38: Personality disorder diagnostic Read
E216.00 Inadequate personality disorder res38: Personality disorder diagnostic Read
E217.00 Antisocial or sociopathic personality disorder res38: Personality disorder diagnostic Read
E21y.00 Other personality disorders res38: Personality disorder diagnostic Read
E21y000 Narcissistic personality disorder res38: Personality disorder diagnostic Read
E21y100 Avoidant personality disorder res38: Personality disorder diagnostic Read
E21y200 Borderline personality disorder res38: Personality disorder diagnostic Read
E21y300 Passive-aggressive personality disorder res38: Personality disorder diagnostic Read
E21y400 Eccentric personality disorder res38: Personality disorder diagnostic Read
E21y500 Immature personality disorder res38: Personality disorder diagnostic Read
E21y600 Masochistic personality disorder res38: Personality disorder diagnostic Read
E21y700 Psychoneurotic personality disorder res38: Personality disorder diagnostic Read
E21yz00 Other personality disorder NOS res38: Personality disorder diagnostic Read
E21z.00 Personality disorder NOS res38: Personality disorder diagnostic Read
E21z.11 Psychopathic personality res38: Personality disorder diagnostic Read
Eu06000 [X]Organic personality disorder res38: Personality disorder diagnostic Read
Eu06011 [X]Organic pseudopsychopathic personality res38: Personality disorder diagnostic Read
Eu21.17 [X]Pseudopsychopathic schizophrenia res38: Personality disorder diagnostic Read
Eu21.18 [X]Schizotypal personality disorder res38: Personality disorder diagnostic Read
Eu34011 [X]Affective personality disorder res38: Personality disorder diagnostic Read
Eu34112 [X]Depressive personality disorder res38: Personality disorder diagnostic Read
Eu60.00 [X]Specific personality disorders res38: Personality disorder diagnostic Read
Eu60000 [X]Paranoid personality disorder res38: Personality disorder diagnostic Read
Eu60013 [X]Querulant personality disorder res38: Personality disorder diagnostic Read
Eu60014 [X]Sensitive paranoid personality disorder res38: Personality disorder diagnostic Read
Eu60100 [X]Schizoid personality disorder res38: Personality disorder diagnostic Read
Eu60200 [X]Dissocial personality disorder res38: Personality disorder diagnostic Read
Eu60212 [X]Antisocial personality disorder res38: Personality disorder diagnostic Read
Eu60213 [X]Asocial personality disorder res38: Personality disorder diagnostic Read
Eu60214 [X]Psychopathic personality disorder res38: Personality disorder diagnostic Read
Eu60215 [X]Sociopathic personality disorder res38: Personality disorder diagnostic Read
Eu60300 [X]Emotionally unstable personality disorder res38: Personality disorder diagnostic Read
Eu60311 [X]Aggressive personality disorder res38: Personality disorder diagnostic Read
Eu60312 [X]Borderline personality disorder res38: Personality disorder diagnostic Read
Eu60313 [X]Explosive personality disorder res38: Personality disorder diagnostic Read
Eu60400 [X]Histrionic personality disorder res38: Personality disorder diagnostic Read
Eu60411 [X]Hysterical personality disorder res38: Personality disorder diagnostic Read
Eu60412 [X]Psychoinfantile personality disorder res38: Personality disorder diagnostic Read
Eu60500 [X]Anankastic personality disorder res38: Personality disorder diagnostic Read
Eu60511 [X]Compulsive personality disorder res38: Personality disorder diagnostic Read
Eu60512 [X]Obsessional personality disorder res38: Personality disorder diagnostic Read
Eu60513 [X]Obsessive-compulsive personality disorder res38: Personality disorder diagnostic Read
Eu60600 [X]Anxious [avoidant] personality disorder res38: Personality disorder diagnostic Read
Eu60700 [X]Dependent personality disorder res38: Personality disorder diagnostic Read
Eu60711 [X]Asthenic personality disorder res38: Personality disorder diagnostic Read
Eu60712 [X]Inadequate personality disorder res38: Personality disorder diagnostic Read
Eu60713 [X]Passive personality disorder res38: Personality disorder diagnostic Read
Eu60714 [X]Self defeating personality disorder res38: Personality disorder diagnostic Read
Eu60y00 [X]Other specific personality disorders res38: Personality disorder diagnostic Read
Eu60y11 [X]Eccentric personality disorder res38: Personality disorder diagnostic Read
Eu60y12 [X]Haltlose type personality disorder res38: Personality disorder diagnostic Read
Eu60y13 [X]Immature personality disorder res38: Personality disorder diagnostic Read
Eu60y14 [X]Narcissistic personality disorder res38: Personality disorder diagnostic Read
Eu60y16 [X]Psychoneurotic personality disorder res38: Personality disorder diagnostic Read
Eu60z00 [X]Personality disorder, unspecified res38: Personality disorder diagnostic Read
Eu61.00 [X]Mixed and other personality disorders res38: Personality disorder diagnostic Read
Eu84511 [X]Autistic psychopathy res38: Personality disorder diagnostic Read
Eu94211 [X]Affectionless psychopathy res38: Personality disorder diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH705/version/1410/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH705/version/1410/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH705', '1410', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH705/version/1410/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH705/version/1410/export/codes/?format=json
CSV site_root/phenotypes/PH705/version/1410/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH705', '1410', api_client=client)

Version History

Version
ID
Name Owner Publish date
1410 Personality Disorder ieuan.scanlon 2021-10-06 currently shown

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