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Antiplatelet Agents

Alison K Wright, Evangelos Kontopantelis, Richard Emsley, Iain Buchan, Naveed Sattar, Martin K Rutter, Darren M. Ashcroft

Type
Drug
ID
PH712
Version ID
1424
Data Sources
Valid event data range
01/01/1998 - 31/03/2015
Sex
Female, Male
Agreement Date
2017-03-30
Coding system
GPRD product codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

OBJECTIVES:

This study 1) investigated life expectancy and cause-specific mortality rates associated with type 2 diabetes and 2) quantified these relationships in ethnic subgroups.

RESEARCH DESIGN AND METHODS:

This was a cohort study using Clinical Practice Research Datalink data from 383 general practices in Englandwith linked hospitalization andmortality records. A total of 187,968 patients with incident type 2 diabetes from 1998 to 2015 were matched to 908,016 control subjects. Abridged life tables estimated years of life lost, and a competing risk survival model quantified cause-specific hazard ratios (HRs).

RESULTS:

A total of 40,286 deaths occurred in patientswith type 2 diabetes. At age 40,white menwith diabetes lost 5 years of life andwhitewomen lost 6 years compared with those without diabetes. A loss of between 1 and 2 years was observed for South Asians and blacks with diabetes. At age older than 65 years, South Asians with diabetes had up to 1.1 years’ longer life expectancy than South Asians without diabetes. Compared with whites with diabetes, South Asians with diabetes had lower adjusted risks formortality fromcardiovascular (HR 0.82; 95% CI 0.75, 0.89), cancer (HR 0.43; 95% CI 0.36, 0.51), and respiratory diseases (HR 0.60; 95% CI 0.48, 0.76). A similar pattern was observed in blacks with diabetes compared with whites with diabetes.

CONCLUSIONS:

Type 2 diabetes was associated with more years of life lost among whites than among South Asians or blacks, with older South Asians experiencing longer life expectancy compared with South Asians without diabetes. The findings support optimized cardiovascular disease risk factor management, especially in whites with type 2 diabetes.

Publications

  • Alison K Wright, Evangelos Kontopantelis, Richard Emsley, Iain Buchan, Naveed Sattar, Martin K Rutter, Darren M. Ashcroft, Life Expectancy and Cause-Specific Mortality in Type 2 Diabetes A Population-Based Cohort Study Quantifying Relationships in Ethnic Subgroups. Diabetes Care, 40(3), 338-345, 2017.

Clinical Code List

Rows: 109
Code Description Coding System (CPRD_product_code) Entity type Category
16 aspirin tablets 75mg CPRD_product_code res56: Antiplatelet agents drug
18329 ENPRIN enteric coated tablets 75mg [GALPHARM] CPRD_product_code res56: Antiplatelet agents drug
19189 MICROPIRIN enteric coated tablets 75mg [RATIOPHARM] CPRD_product_code res56: Antiplatelet agents drug
22618 SOLPRIN tablets 75mg [RECKITT B] CPRD_product_code res56: Antiplatelet agents drug
23593 POSTMI dispersible tablet 75mg [ASHBOURNE] CPRD_product_code res56: Antiplatelet agents drug
23878 NU-SEALS CARDIO EC tablets 75mg [GENUS] CPRD_product_code res56: Antiplatelet agents drug
25335 POSTMI EC tablets 75mg [ASHBOURNE] CPRD_product_code res56: Antiplatelet agents drug
25718 ANGETTES tablets 75mg [BRISTOL] CPRD_product_code res56: Antiplatelet agents drug
2607 PAYNOCIL tablets [BEECHAM] CPRD_product_code res56: Antiplatelet agents drug
2628 NU-SEALS ASPIRIN EC tablets 75mg [LILLY] CPRD_product_code res56: Antiplatelet agents drug
3 aspirin dispersible tablet 75mg CPRD_product_code res56: Antiplatelet agents drug
31211 ASPIRIN dispersible tablet 75mg [AAH(VANT)] CPRD_product_code res56: Antiplatelet agents drug
31938 ASPIRIN EC tablets 75mg [SANDOZ] CPRD_product_code res56: Antiplatelet agents drug
31953 ASPIRIN dispersible tablet 75mg [IVAX] CPRD_product_code res56: Antiplatelet agents drug
31954 ASPIRIN dispersible tablet 75mg [TEVA] CPRD_product_code res56: Antiplatelet agents drug
31956 ASPIRIN enteric coated tablets 75mg [KENT] CPRD_product_code res56: Antiplatelet agents drug
32036 ASPIRIN dispersible tablet 75mg [ACTAVIS] CPRD_product_code res56: Antiplatelet agents drug
32992 ASPIRIN enteric coated tablets 75mg [GEN (UK)] CPRD_product_code res56: Antiplatelet agents drug
33293 ASPIRIN enteric coated tablets 75mg [STERWIN] CPRD_product_code res56: Antiplatelet agents drug
33320 ASPIRIN dispersible tablet 75mg [SOVEREIGN] CPRD_product_code res56: Antiplatelet agents drug
33656 ASPIRIN dispersible tablet 75mg [HILLCROSS] CPRD_product_code res56: Antiplatelet agents drug
33676 ASPIRIN dispersible tablet 75mg [KENT] CPRD_product_code res56: Antiplatelet agents drug
34 aspirin gastro-resistant tablets 75mg CPRD_product_code res56: Antiplatelet agents drug
34385 ASPIRIN soluble tablet 75mg [CO-OPERATI] CPRD_product_code res56: Antiplatelet agents drug
34434 ASPIRIN dispersible tablet 75mg [T & R] CPRD_product_code res56: Antiplatelet agents drug
34485 ASPIRIN enteric coated tablets 75mg [IVAX] CPRD_product_code res56: Antiplatelet agents drug
34611 ASPIRIN enteric coated tablets 75mg [CP PHARM] CPRD_product_code res56: Antiplatelet agents drug
34796 ASPIRIN enteric coated tablets 75mg [GALEN] CPRD_product_code res56: Antiplatelet agents drug
34797 ASPIRIN enteric coated tablets 75mg [ACTAVIS] CPRD_product_code res56: Antiplatelet agents drug
34942 ASPIRIN dispersible tablet 75mg [NUCARE] CPRD_product_code res56: Antiplatelet agents drug
40381 ASPIRIN soluble tablet 75mg [CP PHARM] CPRD_product_code res56: Antiplatelet agents drug
40913 GREPID film coated tablets 75mg [BEACON] CPRD_product_code res56: Antiplatelet agents drug
41512 ASPIRIN enteric coated tablets 75mg [TEVA] CPRD_product_code res56: Antiplatelet agents drug
42750 CLOPIDOGREL film coated tablets 75mg [ACTAVIS] CPRD_product_code res56: Antiplatelet agents drug
43709 ASPIRIN enteric coated tablets 75mg [ALMUS] CPRD_product_code res56: Antiplatelet agents drug
45643 ASPIRIN soluble tablet 75mg [CELLTECH] CPRD_product_code res56: Antiplatelet agents drug
46891 clopidogrel oral suspension 75mg/5ml CPRD_product_code res56: Antiplatelet agents drug
47937 ASPIRIN dispersible tablet 75mg [WOCKHARDT] CPRD_product_code res56: Antiplatelet agents drug
47992 ASPIRIN enteric coated tablets 75mg [HILLCROSS] CPRD_product_code res56: Antiplatelet agents drug
48021 ASPIRIN tablets 75mg [HILLCROSS] CPRD_product_code res56: Antiplatelet agents drug
48165 Aspirin 300mg tablets (Aspar Pharmaceuticals Ltd) CPRD_product_code res56: Antiplatelet agents drug
489 clopidogrel film coated tablets 75mg CPRD_product_code res56: Antiplatelet agents drug
48974 Aspirin 75mg tablets (Phoenix Healthcare Distribution Ltd) CPRD_product_code res56: Antiplatelet agents drug
49060 Aspirin 75mg dispersible tablets (Alliance Healthcare (Distribution) Ltd) CPRD_product_code res56: Antiplatelet agents drug
49220 Aspirin 300mg tablets (Kent Pharmaceuticals Ltd) CPRD_product_code res56: Antiplatelet agents drug
49685 Aspirin 75mg dispersible tablets (Sigma Pharmaceuticals Plc) CPRD_product_code res56: Antiplatelet agents drug
49799 Aspirin 150mg suppositories (A A H Pharmaceuticals Ltd) CPRD_product_code res56: Antiplatelet agents drug
50555 Aspirin 300mg dispersible tablets (DE Pharmaceuticals) CPRD_product_code res56: Antiplatelet agents drug
50926 Aspirin 75mg dispersible tablets (The Boots Company Plc) CPRD_product_code res56: Antiplatelet agents drug
50949 Aspirin 75mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res56: Antiplatelet agents drug
51474 Aspirin 150mg suppositories (Martindale Pharmaceuticals Ltd) CPRD_product_code res56: Antiplatelet agents drug
51561 Aspirin 75mg gastro-resistant tablets (Zanza Laboratories Ltd) CPRD_product_code res56: Antiplatelet agents drug
52044 Aspirin 300mg caplets (The Boots Company Plc) CPRD_product_code res56: Antiplatelet agents drug
52280 Aspirin 300mg Tablet (Wockhardt UK Ltd) CPRD_product_code res56: Antiplatelet agents drug
52618 Aspirin 75mg dispersible tablets (Bristol Laboratories Ltd) CPRD_product_code res56: Antiplatelet agents drug
52761 Clopidogrel 75mg tablets (Dr Reddy's Laboratories (UK) Ltd) CPRD_product_code res56: Antiplatelet agents drug
52905 Aspirin 300mg tablets (Lloyds Pharmacy Ltd) CPRD_product_code res56: Antiplatelet agents drug
53178 Aspirin 75mg gastro-resistant tablets (Wockhardt UK Ltd) CPRD_product_code res56: Antiplatelet agents drug
53622 Aspirin 300mg Tablet (M & A Pharmachem Ltd) CPRD_product_code res56: Antiplatelet agents drug
53711 Aspirin 300mg Tablet (Nucare Plc) CPRD_product_code res56: Antiplatelet agents drug
53751 Clopidogrel 75mg tablets (Phoenix Healthcare Distribution Ltd) CPRD_product_code res56: Antiplatelet agents drug
53791 Aspirin 150mg suppositories (Alliance Healthcare (Distribution) Ltd) CPRD_product_code res56: Antiplatelet agents drug
53804 Aspirin 300mg gastro-resistant tablets (Alliance Healthcare (Distribution) Ltd) CPRD_product_code res56: Antiplatelet agents drug
53816 Aspirin 300mg dispersible tablets (Alliance Healthcare (Distribution) Ltd) CPRD_product_code res56: Antiplatelet agents drug
54284 Aspirin 75mg dispersible tablets (Almus Pharmaceuticals Ltd) CPRD_product_code res56: Antiplatelet agents drug
54430 Aspirin 75mg tablets (Alliance Healthcare (Distribution) Ltd) CPRD_product_code res56: Antiplatelet agents drug
54526 Aspirin 300mg tablets (Alliance Healthcare (Distribution) Ltd) CPRD_product_code res56: Antiplatelet agents drug
54565 Aspirin 75mg dispersible tablets (Lloyds Pharmacy Ltd) CPRD_product_code res56: Antiplatelet agents drug
54700 Clopidogrel 75mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res56: Antiplatelet agents drug
54734 Aspirin 300mg tablets (Wockhardt UK Ltd) CPRD_product_code res56: Antiplatelet agents drug
54997 Aspirin 75mg dispersible tablets (Dowelhurst Ltd) CPRD_product_code res56: Antiplatelet agents drug
55161 Clopidogrel 75mg tablets (Wockhardt UK Ltd) CPRD_product_code res56: Antiplatelet agents drug
56007 Aspirin 300mg dispersible tablets (Sigma Pharmaceuticals Plc) CPRD_product_code res56: Antiplatelet agents drug
56503 Asasantin Retard capsules (Mawdsley-Brooks & Company Ltd) CPRD_product_code res56: Antiplatelet agents drug
56736 Aspirin 300mg tablets (Waymade Healthcare Plc) CPRD_product_code res56: Antiplatelet agents drug
56807 Clopidogrel 75mg tablets (Teva UK Ltd) CPRD_product_code res56: Antiplatelet agents drug
56883 Aspirin 75mg tablets (Waymade Healthcare Plc) CPRD_product_code res56: Antiplatelet agents drug
56995 Aspirin 75mg dispersible tablets (Phoenix Healthcare Distribution Ltd) CPRD_product_code res56: Antiplatelet agents drug
56996 Aspirin 75mg dispersible tablets (Waymade Healthcare Plc) CPRD_product_code res56: Antiplatelet agents drug
57036 Clopidogrel 75mg tablets (Mylan Ltd) CPRD_product_code res56: Antiplatelet agents drug
57057 Aspirin 75mg dispersible tablets (Wockhardt UK Ltd) CPRD_product_code res56: Antiplatelet agents drug
58331 Aspirin 300mg gastro-resistant tablets (Mylan Ltd) CPRD_product_code res56: Antiplatelet agents drug
58347 Clopidogrel 75mg tablets (DE Pharmaceuticals) CPRD_product_code res56: Antiplatelet agents drug
58448 Clopidogrel 75mg tablets (Aspire Pharma Ltd) CPRD_product_code res56: Antiplatelet agents drug
59021 Aspirin 75mg gastro-resistant tablets (Bristol Laboratories Ltd) CPRD_product_code res56: Antiplatelet agents drug
59253 Aspirin 75mg gastro-resistant tablets (Waymade Healthcare Plc) CPRD_product_code res56: Antiplatelet agents drug
59728 Aspirin 75mg tablets (Alissa Healthcare Research Ltd) CPRD_product_code res56: Antiplatelet agents drug
59791 Aspirin 75mg dispersible tablets (Aspar Pharmaceuticals Ltd) CPRD_product_code res56: Antiplatelet agents drug
59904 Clopidogrel 75mg/5ml oral solution CPRD_product_code res56: Antiplatelet agents drug
6006 NU-SEALS ASPIRIN EC tablets 75mg [ALLIANCE] CPRD_product_code res56: Antiplatelet agents drug
60127 Aspirin 75mg tablets (DE Pharmaceuticals) CPRD_product_code res56: Antiplatelet agents drug
60278 Aspirin 300mg tablets (DE Pharmaceuticals) CPRD_product_code res56: Antiplatelet agents drug
60694 Aspirin 25mg/5ml oral solution CPRD_product_code res56: Antiplatelet agents drug
60777 Aspirin 75mg gastro-resistant tablets (DE Pharmaceuticals) CPRD_product_code res56: Antiplatelet agents drug
62334 Aspirin 300mg caplets (Wockhardt UK Ltd) CPRD_product_code res56: Antiplatelet agents drug
62430 Aspirin 300mg suppositories (A A H Pharmaceuticals Ltd) CPRD_product_code res56: Antiplatelet agents drug
62855 Clopidogrel 75mg tablets (Alliance Healthcare (Distribution) Ltd) CPRD_product_code res56: Antiplatelet agents drug
62978 Clopidogrel 75mg tablets (Sandoz Ltd) CPRD_product_code res56: Antiplatelet agents drug
63450 Clopidogrel 75mg tablets (Almus Pharmaceuticals Ltd) CPRD_product_code res56: Antiplatelet agents drug
63603 Laboprin Tablet (Laboratories For Applied Biology Ltd) CPRD_product_code res56: Antiplatelet agents drug
64071 Aspirin powder (J M Loveridge Ltd) CPRD_product_code res56: Antiplatelet agents drug
65909 Clopidogrel 75mg tablets (Milpharm Ltd) CPRD_product_code res56: Antiplatelet agents drug
66345 Aspirin 75mg dispersible tablets (DE Pharmaceuticals) CPRD_product_code res56: Antiplatelet agents drug
66546 Aspirin 75mg dispersible tablets (Numark Management Ltd) CPRD_product_code res56: Antiplatelet agents drug
66563 Aspirin 75mg gastro-resistant tablets (Phoenix Healthcare Distribution Ltd) CPRD_product_code res56: Antiplatelet agents drug
66861 Aspirin 75mg effervescent tablets CPRD_product_code res56: Antiplatelet agents drug
6696 MICROPIRIN enteric coated tablets 75mg [DEXCEL] CPRD_product_code res56: Antiplatelet agents drug
836 PLAVIX film coated tablets 75mg [SANOFI BMS] CPRD_product_code res56: Antiplatelet agents drug
9144 CAPRIN EC tablets 75mg [WOCKHARDT] CPRD_product_code res56: Antiplatelet agents drug

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH712/version/1424/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH712/version/1424/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH712', '1424', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH712/version/1424/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH712/version/1424/export/codes/?format=json
CSV site_root/phenotypes/PH712/version/1424/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH712', '1424', api_client=client)

Version History

Version
ID
Name Owner Publish date
1424 Antiplatelet Agents ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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