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Cardiovascular Disease

Alison K Wright, Evangelos Kontopantelis, Richard Emsley, Iain Buchan, Naveed Sattar, Martin K Rutter, Darren M. Ashcroft

Type
Disease or Syndrome
ID
PH713
Version ID
1426
Data Sources
Valid event data range
01/01/1998 - 31/03/2015
Sex
Female, Male
Agreement Date
2017-03-30
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

OBJECTIVES:

This study 1) investigated life expectancy and cause-specific mortality rates associated with type 2 diabetes and 2) quantified these relationships in ethnic subgroups.

RESEARCH DESIGN AND METHODS:

This was a cohort study using Clinical Practice Research Datalink data from 383 general practices in Englandwith linked hospitalization andmortality records. A total of 187,968 patients with incident type 2 diabetes from 1998 to 2015 were matched to 908,016 control subjects. Abridged life tables estimated years of life lost, and a competing risk survival model quantified cause-specific hazard ratios (HRs).

RESULTS:

A total of 40,286 deaths occurred in patientswith type 2 diabetes. At age 40,white menwith diabetes lost 5 years of life andwhitewomen lost 6 years compared with those without diabetes. A loss of between 1 and 2 years was observed for South Asians and blacks with diabetes. At age older than 65 years, South Asians with diabetes had up to 1.1 years’ longer life expectancy than South Asians without diabetes. Compared with whites with diabetes, South Asians with diabetes had lower adjusted risks formortality fromcardiovascular (HR 0.82; 95% CI 0.75, 0.89), cancer (HR 0.43; 95% CI 0.36, 0.51), and respiratory diseases (HR 0.60; 95% CI 0.48, 0.76). A similar pattern was observed in blacks with diabetes compared with whites with diabetes.

CONCLUSIONS:

Type 2 diabetes was associated with more years of life lost among whites than among South Asians or blacks, with older South Asians experiencing longer life expectancy compared with South Asians without diabetes. The findings support optimized cardiovascular disease risk factor management, especially in whites with type 2 diabetes.

Publications

  • Alison K Wright, Evangelos Kontopantelis, Richard Emsley, Iain Buchan, Naveed Sattar, Martin K Rutter, Darren M. Ashcroft, Life Expectancy and Cause-Specific Mortality in Type 2 Diabetes: A Population-Based Cohort Study Quantifying Relationships in Ethnic Subgroups. Diabetes Care, 40(3), 338-345, 2017.

Clinical Code List

Rows: 190
Code Description Entity type Category Coding System (Read)
G3...00 Ischaemic heart disease res56: Cardiovascular Disease diagnostic Read
G3...11 Arteriosclerotic heart disease res56: Cardiovascular Disease diagnostic Read
G3...12 Atherosclerotic heart disease res56: Cardiovascular Disease diagnostic Read
G3...13 IHD - Ischaemic heart disease res56: Cardiovascular Disease diagnostic Read
G30..00 Acute myocardial infarction res56: Cardiovascular Disease diagnostic Read
G30..12 Coronary thrombosis res56: Cardiovascular Disease diagnostic Read
G30..13 Cardiac rupture following myocardial infarction (MI) res56: Cardiovascular Disease diagnostic Read
G30..15 MI - acute myocardial infarction res56: Cardiovascular Disease diagnostic Read
G30..16 Thrombosis - coronary res56: Cardiovascular Disease diagnostic Read
G30..17 Silent myocardial infarction res56: Cardiovascular Disease diagnostic Read
G300.00 Acute anterolateral infarction res56: Cardiovascular Disease diagnostic Read
G301.00 Other specified anterior myocardial infarction res56: Cardiovascular Disease diagnostic Read
G301000 Acute anteroapical infarction res56: Cardiovascular Disease diagnostic Read
G301100 Acute anteroseptal infarction res56: Cardiovascular Disease diagnostic Read
G301z00 Anterior myocardial infarction NOS res56: Cardiovascular Disease diagnostic Read
G302.00 Acute inferolateral infarction res56: Cardiovascular Disease diagnostic Read
G303.00 Acute inferoposterior infarction res56: Cardiovascular Disease diagnostic Read
G304.00 Posterior myocardial infarction NOS res56: Cardiovascular Disease diagnostic Read
G305.00 Lateral myocardial infarction NOS res56: Cardiovascular Disease diagnostic Read
G306.00 True posterior myocardial infarction res56: Cardiovascular Disease diagnostic Read
G307.00 Acute subendocardial infarction res56: Cardiovascular Disease diagnostic Read
G307000 Acute non-Q wave infarction res56: Cardiovascular Disease diagnostic Read
G307100 Acute non-ST segment elevation myocardial infarction res56: Cardiovascular Disease diagnostic Read
G308.00 Inferior myocardial infarction NOS res56: Cardiovascular Disease diagnostic Read
G309.00 Acute Q-wave infarct res56: Cardiovascular Disease diagnostic Read
G30B.00 Acute posterolateral myocardial infarction res56: Cardiovascular Disease diagnostic Read
G30X.00 Acute transmural myocardial infarction of unspecif site res56: Cardiovascular Disease diagnostic Read
G30X000 Acute ST segment elevation myocardial infarction res56: Cardiovascular Disease diagnostic Read
G30y.00 Other acute myocardial infarction res56: Cardiovascular Disease diagnostic Read
G30y100 Acute papillary muscle infarction res56: Cardiovascular Disease diagnostic Read
G30y200 Acute septal infarction res56: Cardiovascular Disease diagnostic Read
G30yz00 Other acute myocardial infarction NOS res56: Cardiovascular Disease diagnostic Read
G30z.00 Acute myocardial infarction NOS res56: Cardiovascular Disease diagnostic Read
G31..00 Other acute and subacute ischaemic heart disease res56: Cardiovascular Disease diagnostic Read
G310.00 Postmyocardial infarction syndrome res56: Cardiovascular Disease diagnostic Read
G310.11 Dressler's syndrome res56: Cardiovascular Disease diagnostic Read
G311.00 Preinfarction syndrome res56: Cardiovascular Disease diagnostic Read
G311.11 Crescendo angina res56: Cardiovascular Disease diagnostic Read
G311.12 Impending infarction res56: Cardiovascular Disease diagnostic Read
G311.13 Unstable angina res56: Cardiovascular Disease diagnostic Read
G311.14 Angina at rest res56: Cardiovascular Disease diagnostic Read
G311000 Myocardial infarction aborted res56: Cardiovascular Disease diagnostic Read
G311011 MI - myocardial infarction aborted res56: Cardiovascular Disease diagnostic Read
G311100 Unstable angina res56: Cardiovascular Disease diagnostic Read
G311200 Angina at rest res56: Cardiovascular Disease diagnostic Read
G311300 Refractory angina res56: Cardiovascular Disease diagnostic Read
G311500 Acute coronary syndrome res56: Cardiovascular Disease diagnostic Read
G311z00 Preinfarction syndrome NOS res56: Cardiovascular Disease diagnostic Read
G31y.00 Other acute and subacute ischaemic heart disease res56: Cardiovascular Disease diagnostic Read
G31y000 Acute coronary insufficiency res56: Cardiovascular Disease diagnostic Read
G31y200 Subendocardial ischaemia res56: Cardiovascular Disease diagnostic Read
G31y300 Transient myocardial ischaemia res56: Cardiovascular Disease diagnostic Read
G31yz00 Other acute and subacute ischaemic heart disease NOS res56: Cardiovascular Disease diagnostic Read
G32..00 Old myocardial infarction res56: Cardiovascular Disease diagnostic Read
G32..11 Healed myocardial infarction res56: Cardiovascular Disease diagnostic Read
G32..12 Personal history of myocardial infarction res56: Cardiovascular Disease diagnostic Read
G33..00 Angina pectoris res56: Cardiovascular Disease diagnostic Read
G330.00 Angina decubitus res56: Cardiovascular Disease diagnostic Read
G330000 Nocturnal angina res56: Cardiovascular Disease diagnostic Read
G330z00 Angina decubitus NOS res56: Cardiovascular Disease diagnostic Read
G331.00 Prinzmetal's angina res56: Cardiovascular Disease diagnostic Read
G331.11 Variant angina pectoris res56: Cardiovascular Disease diagnostic Read
G332.00 Coronary artery spasm res56: Cardiovascular Disease diagnostic Read
G33z.00 Angina pectoris NOS res56: Cardiovascular Disease diagnostic Read
G33z000 Status anginosus res56: Cardiovascular Disease diagnostic Read
G33z100 Stenocardia res56: Cardiovascular Disease diagnostic Read
G33z200 Syncope anginosa res56: Cardiovascular Disease diagnostic Read
G33z300 Angina on effort res56: Cardiovascular Disease diagnostic Read
G33z400 Ischaemic chest pain res56: Cardiovascular Disease diagnostic Read
G33z500 Post infarct angina res56: Cardiovascular Disease diagnostic Read
G33z600 New onset angina res56: Cardiovascular Disease diagnostic Read
G33z700 Stable angina res56: Cardiovascular Disease diagnostic Read
G33zz00 Angina pectoris NOS res56: Cardiovascular Disease diagnostic Read
G34..00 Other chronic ischaemic heart disease res56: Cardiovascular Disease diagnostic Read
G340.00 Coronary atherosclerosis res56: Cardiovascular Disease diagnostic Read
G340.11 Triple vessel disease of the heart res56: Cardiovascular Disease diagnostic Read
G340.12 Coronary artery disease res56: Cardiovascular Disease diagnostic Read
G340000 Single coronary vessel disease res56: Cardiovascular Disease diagnostic Read
G340100 Double coronary vessel disease res56: Cardiovascular Disease diagnostic Read
G342.00 Atherosclerotic cardiovascular disease res56: Cardiovascular Disease diagnostic Read
G343.00 Ischaemic cardiomyopathy res56: Cardiovascular Disease diagnostic Read
G344.00 Silent myocardial ischaemia res56: Cardiovascular Disease diagnostic Read
G34y.00 Other specified chronic ischaemic heart disease res56: Cardiovascular Disease diagnostic Read
G34y000 Chronic coronary insufficiency res56: Cardiovascular Disease diagnostic Read
G34y100 Chronic myocardial ischaemia res56: Cardiovascular Disease diagnostic Read
G34yz00 Other specified chronic ischaemic heart disease NOS res56: Cardiovascular Disease diagnostic Read
G34z.00 Other chronic ischaemic heart disease NOS res56: Cardiovascular Disease diagnostic Read
G34z000 Asymptomatic coronary heart disease res56: Cardiovascular Disease diagnostic Read
G35..00 Subsequent myocardial infarction res56: Cardiovascular Disease diagnostic Read
G350.00 Subsequent myocardial infarction of anterior wall res56: Cardiovascular Disease diagnostic Read
G351.00 Subsequent myocardial infarction of inferior wall res56: Cardiovascular Disease diagnostic Read
G353.00 Subsequent myocardial infarction of other sites res56: Cardiovascular Disease diagnostic Read
G35X.00 Subsequent myocardial infarction of unspecified site res56: Cardiovascular Disease diagnostic Read
G360.00 Haemopericardium/current comp folow acut myocard infarct res56: Cardiovascular Disease diagnostic Read
G362.00 Ventric septal defect/curr comp fol acut myocardal infarctn res56: Cardiovascular Disease diagnostic Read
G363.00 Ruptur cardiac wall w'out haemopericard/cur comp fol ac MI res56: Cardiovascular Disease diagnostic Read
G364.00 Ruptur chordae tendinae/curr comp fol acute myocard infarct res56: Cardiovascular Disease diagnostic Read
G365.00 Rupture papillary muscle/curr comp fol acute myocard infarct res56: Cardiovascular Disease diagnostic Read
G38..00 Postoperative myocardial infarction res56: Cardiovascular Disease diagnostic Read
G380.00 Postoperative transmural myocardial infarction anterior wall res56: Cardiovascular Disease diagnostic Read
G381.00 Postoperative transmural myocardial infarction inferior wall res56: Cardiovascular Disease diagnostic Read
G384.00 Postoperative subendocardial myocardial infarction res56: Cardiovascular Disease diagnostic Read
G38z.00 Postoperative myocardial infarction, unspecified res56: Cardiovascular Disease diagnostic Read
G3y..00 Other specified ischaemic heart disease res56: Cardiovascular Disease diagnostic Read
G3z..00 Ischaemic heart disease NOS res56: Cardiovascular Disease diagnostic Read
G574011 Cardiac arrest-ventricular fibrillation res56: Cardiovascular Disease diagnostic Read
G575.00 Cardiac arrest res56: Cardiovascular Disease diagnostic Read
G575.11 Cardio-respiratory arrest res56: Cardiovascular Disease diagnostic Read
G575.12 Asystole res56: Cardiovascular Disease diagnostic Read
G575000 Cardiac arrest with successful resuscitation res56: Cardiovascular Disease diagnostic Read
G575100 Sudden cardiac death, so described res56: Cardiovascular Disease diagnostic Read
G575z00 Cardiac arrest, unspecified res56: Cardiovascular Disease diagnostic Read
G61..00 Intracerebral haemorrhage res56: Cardiovascular Disease diagnostic Read
G61..11 CVA - cerebrovascular accid due to intracerebral haemorrhage res56: Cardiovascular Disease diagnostic Read
G61..12 Stroke due to intracerebral haemorrhage res56: Cardiovascular Disease diagnostic Read
G610.00 Cortical haemorrhage res56: Cardiovascular Disease diagnostic Read
G611.00 Internal capsule haemorrhage res56: Cardiovascular Disease diagnostic Read
G612.00 Basal nucleus haemorrhage res56: Cardiovascular Disease diagnostic Read
G613.00 Cerebellar haemorrhage res56: Cardiovascular Disease diagnostic Read
G614.00 Pontine haemorrhage res56: Cardiovascular Disease diagnostic Read
G615.00 Bulbar haemorrhage res56: Cardiovascular Disease diagnostic Read
G616.00 External capsule haemorrhage res56: Cardiovascular Disease diagnostic Read
G617.00 Intracerebral haemorrhage, intraventricular res56: Cardiovascular Disease diagnostic Read
G618.00 Intracerebral haemorrhage, multiple localized res56: Cardiovascular Disease diagnostic Read
G61X.00 Intracerebral haemorrhage in hemisphere, unspecified res56: Cardiovascular Disease diagnostic Read
G61X000 Left sided intracerebral haemorrhage, unspecified res56: Cardiovascular Disease diagnostic Read
G61X100 Right sided intracerebral haemorrhage, unspecified res56: Cardiovascular Disease diagnostic Read
G61z.00 Intracerebral haemorrhage NOS res56: Cardiovascular Disease diagnostic Read
G63..00 Precerebral arterial occlusion res56: Cardiovascular Disease diagnostic Read
G63..11 Infarction - precerebral res56: Cardiovascular Disease diagnostic Read
G632.00 Vertebral artery occlusion res56: Cardiovascular Disease diagnostic Read
G63y000 Cerebral infarct due to thrombosis of precerebral arteries res56: Cardiovascular Disease diagnostic Read
G63y100 Cerebral infarction due to embolism of precerebral arteries res56: Cardiovascular Disease diagnostic Read
G64..12 Infarction - cerebral res56: Cardiovascular Disease diagnostic Read
G64..13 Stroke due to cerebral arterial occlusion res56: Cardiovascular Disease diagnostic Read
G640.00 Cerebral thrombosis res56: Cardiovascular Disease diagnostic Read
G640000 Cerebral infarction due to thrombosis of cerebral arteries res56: Cardiovascular Disease diagnostic Read
G641.00 Cerebral embolism res56: Cardiovascular Disease diagnostic Read
G641.11 Cerebral embolus res56: Cardiovascular Disease diagnostic Read
G641000 Cerebral infarction due to embolism of cerebral arteries res56: Cardiovascular Disease diagnostic Read
G64z.00 Cerebral infarction NOS res56: Cardiovascular Disease diagnostic Read
G64z.11 Brainstem infarction NOS res56: Cardiovascular Disease diagnostic Read
G64z.12 Cerebellar infarction res56: Cardiovascular Disease diagnostic Read
G64z000 Brainstem infarction res56: Cardiovascular Disease diagnostic Read
G64z111 Lateral medullary syndrome res56: Cardiovascular Disease diagnostic Read
G64z200 Left sided cerebral infarction res56: Cardiovascular Disease diagnostic Read
G64z300 Right sided cerebral infarction res56: Cardiovascular Disease diagnostic Read
G64z400 Infarction of basal ganglia res56: Cardiovascular Disease diagnostic Read
G66..00 Stroke and cerebrovascular accident unspecified res56: Cardiovascular Disease diagnostic Read
G66..11 CVA unspecified res56: Cardiovascular Disease diagnostic Read
G66..12 Stroke unspecified res56: Cardiovascular Disease diagnostic Read
G66..13 CVA - Cerebrovascular accident unspecified res56: Cardiovascular Disease diagnostic Read
G661.00 Anterior cerebral artery syndrome res56: Cardiovascular Disease diagnostic Read
G662.00 Posterior cerebral artery syndrome res56: Cardiovascular Disease diagnostic Read
G663.00 Brain stem stroke syndrome res56: Cardiovascular Disease diagnostic Read
G664.00 Cerebellar stroke syndrome res56: Cardiovascular Disease diagnostic Read
G665.00 Pure motor lacunar syndrome res56: Cardiovascular Disease diagnostic Read
G666.00 Pure sensory lacunar syndrome res56: Cardiovascular Disease diagnostic Read
G667.00 Left sided CVA res56: Cardiovascular Disease diagnostic Read
G668.00 Right sided CVA res56: Cardiovascular Disease diagnostic Read
G671.00 Generalised ischaemic cerebrovascular disease NOS res56: Cardiovascular Disease diagnostic Read
G671000 Acute cerebrovascular insufficiency NOS res56: Cardiovascular Disease diagnostic Read
G671z00 Generalised ischaemic cerebrovascular disease NOS res56: Cardiovascular Disease diagnostic Read
G676000 Cereb infarct due cerebral venous thrombosis, nonpyogenic res56: Cardiovascular Disease diagnostic Read
G6W..00 Cereb infarct due unsp occlus/stenos precerebr arteries res56: Cardiovascular Disease diagnostic Read
G6X..00 Cerebrl infarctn due/unspcf occlusn or sten/cerebrl artrs res56: Cardiovascular Disease diagnostic Read
G70..00 Atherosclerosis res56: Cardiovascular Disease diagnostic Read
G700.00 Aortic atherosclerosis res56: Cardiovascular Disease diagnostic Read
G73..00 Other peripheral vascular disease res56: Cardiovascular Disease diagnostic Read
G73..12 Ischaemia of legs res56: Cardiovascular Disease diagnostic Read
G73y.00 Other specified peripheral vascular disease res56: Cardiovascular Disease diagnostic Read
G73yz00 Other specified peripheral vascular disease NOS res56: Cardiovascular Disease diagnostic Read
G73z.00 Peripheral vascular disease NOS res56: Cardiovascular Disease diagnostic Read
G73z000 Intermittent claudication res56: Cardiovascular Disease diagnostic Read
G73z011 Claudication res56: Cardiovascular Disease diagnostic Read
G73zz00 Peripheral vascular disease NOS res56: Cardiovascular Disease diagnostic Read
G742z00 Peripheral arterial embolism and thrombosis NOS res56: Cardiovascular Disease diagnostic Read
G74y300 Embolism and thrombosis of the iliac artery unspecified res56: Cardiovascular Disease diagnostic Read
G76z000 Iliac artery occlusion res56: Cardiovascular Disease diagnostic Read
Gyu3.00 [X]Ischaemic heart diseases res56: Cardiovascular Disease diagnostic Read
Gyu3200 [X]Other forms of acute ischaemic heart disease res56: Cardiovascular Disease diagnostic Read
Gyu3300 [X]Other forms of chronic ischaemic heart disease res56: Cardiovascular Disease diagnostic Read
Gyu3400 [X]Acute transmural myocardial infarction of unspecif site res56: Cardiovascular Disease diagnostic Read
Gyu3600 [X]Subsequent myocardial infarction of unspecified site res56: Cardiovascular Disease diagnostic Read
Gyu6200 [X]Other intracerebral haemorrhage res56: Cardiovascular Disease diagnostic Read
Gyu6300 [X]Cerebrl infarctn due/unspcf occlusn or sten/cerebrl artrs res56: Cardiovascular Disease diagnostic Read
Gyu6400 [X]Other cerebral infarction res56: Cardiovascular Disease diagnostic Read
Gyu6F00 [X]Intracerebral haemorrhage in hemisphere, unspecified res56: Cardiovascular Disease diagnostic Read
Gyu6G00 [X]Cereb infarct due unsp occlus/stenos precerebr arteries res56: Cardiovascular Disease diagnostic Read
Gyu7400 [X]Other specified peripheral vascular diseases res56: Cardiovascular Disease diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH713/version/1426/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH713/version/1426/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH713', '1426', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH713/version/1426/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH713/version/1426/export/codes/?format=json
CSV site_root/phenotypes/PH713/version/1426/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH713', '1426', api_client=client)

Version History

Version
ID
Name Owner Publish date
1426 Cardiovascular Disease ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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