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Type 2 Diabetes

Alison K Wright, Evangelos Kontopantelis, Richard Emsley, Iain Buchan, Naveed Sattar, Martin K Rutter, Darren M. Ashcroft

Type
Disease or Syndrome
ID
PH718
Version ID
1436
Data Sources
Valid event data range
01/01/1998 - 31/03/2015
Sex
Female, Male
Agreement Date
2017-03-30
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

OBJECTIVES:

This study 1) investigated life expectancy and cause-specific mortality rates associated with type 2 diabetes and 2) quantified these relationships in ethnic subgroups.

RESEARCH DESIGN AND METHODS:

This was a cohort study using Clinical Practice Research Datalink data from 383 general practices in Englandwith linked hospitalization andmortality records. A total of 187,968 patients with incident type 2 diabetes from 1998 to 2015 were matched to 908,016 control subjects. Abridged life tables estimated years of life lost, and a competing risk survival model quantified cause-specific hazard ratios (HRs).

RESULTS:

A total of 40,286 deaths occurred in patientswith type 2 diabetes. At age 40,white menwith diabetes lost 5 years of life andwhitewomen lost 6 years compared with those without diabetes. A loss of between 1 and 2 years was observed for South Asians and blacks with diabetes. At age older than 65 years, South Asians with diabetes had up to 1.1 years’ longer life expectancy than South Asians without diabetes. Compared with whites with diabetes, South Asians with diabetes had lower adjusted risks formortality fromcardiovascular (HR 0.82; 95% CI 0.75, 0.89), cancer (HR 0.43; 95% CI 0.36, 0.51), and respiratory diseases (HR 0.60; 95% CI 0.48, 0.76). A similar pattern was observed in blacks with diabetes compared with whites with diabetes.

CONCLUSIONS:

Type 2 diabetes was associated with more years of life lost among whites than among South Asians or blacks, with older South Asians experiencing longer life expectancy compared with South Asians without diabetes. The findings support optimized cardiovascular disease risk factor management, especially in whites with type 2 diabetes.

Publications

  • Alison K Wright, Evangelos Kontopantelis, Richard Emsley, Iain Buchan, Naveed Sattar, Martin K Rutter, Darren M. Ashcroft, Life Expectancy and Cause-Specific Mortality in Type 2 Diabetes A Population-Based Cohort Study Quantifying Relationships in Ethnic Subgroups. Diabetes Care, 40(3), 338-345, 2017.

Clinical Code List

Rows: 105
Code Description Entity type Category Coding System (Read)
C100112 Non-insulin dependent diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C103y00 Other specified diabetes mellitus with coma res56: Type 2 Diabetes diagnostic Read
C109.00 Non-insulin dependent diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C109.11 NIDDM - Non-insulin dependent diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C109.12 Type 2 diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C109.13 Type II diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C109000 Non-insulin-dependent diabetes mellitus with renal comps res56: Type 2 Diabetes diagnostic Read
C109011 Type II diabetes mellitus with renal complications res56: Type 2 Diabetes diagnostic Read
C109012 Type 2 diabetes mellitus with renal complications res56: Type 2 Diabetes diagnostic Read
C109100 Non-insulin-dependent diabetes mellitus with ophthalm comps res56: Type 2 Diabetes diagnostic Read
C109111 Type II diabetes mellitus with ophthalmic complications res56: Type 2 Diabetes diagnostic Read
C109112 Type 2 diabetes mellitus with ophthalmic complications res56: Type 2 Diabetes diagnostic Read
C109200 Non-insulin-dependent diabetes mellitus with neuro comps res56: Type 2 Diabetes diagnostic Read
C109211 Type II diabetes mellitus with neurological complications res56: Type 2 Diabetes diagnostic Read
C109212 Type 2 diabetes mellitus with neurological complications res56: Type 2 Diabetes diagnostic Read
C109300 Non-insulin-dependent diabetes mellitus with multiple comps res56: Type 2 Diabetes diagnostic Read
C109312 Type 2 diabetes mellitus with multiple complications res56: Type 2 Diabetes diagnostic Read
C109400 Non-insulin dependent diabetes mellitus with ulcer res56: Type 2 Diabetes diagnostic Read
C109411 Type II diabetes mellitus with ulcer res56: Type 2 Diabetes diagnostic Read
C109412 Type 2 diabetes mellitus with ulcer res56: Type 2 Diabetes diagnostic Read
C109500 Non-insulin dependent diabetes mellitus with gangrene res56: Type 2 Diabetes diagnostic Read
C109511 Type II diabetes mellitus with gangrene res56: Type 2 Diabetes diagnostic Read
C109512 Type 2 diabetes mellitus with gangrene res56: Type 2 Diabetes diagnostic Read
C109600 Non-insulin-dependent diabetes mellitus with retinopathy res56: Type 2 Diabetes diagnostic Read
C109611 Type II diabetes mellitus with retinopathy res56: Type 2 Diabetes diagnostic Read
C109612 Type 2 diabetes mellitus with retinopathy res56: Type 2 Diabetes diagnostic Read
C109700 Non-insulin dependent diabetes mellitus - poor control res56: Type 2 Diabetes diagnostic Read
C109711 Type II diabetes mellitus - poor control res56: Type 2 Diabetes diagnostic Read
C109712 Type 2 diabetes mellitus - poor control res56: Type 2 Diabetes diagnostic Read
C109900 Non-insulin-dependent diabetes mellitus without complication res56: Type 2 Diabetes diagnostic Read
C109911 Type II diabetes mellitus without complication res56: Type 2 Diabetes diagnostic Read
C109912 Type 2 diabetes mellitus without complication res56: Type 2 Diabetes diagnostic Read
C109A00 Non-insulin dependent diabetes mellitus with mononeuropathy res56: Type 2 Diabetes diagnostic Read
C109A11 Type II diabetes mellitus with mononeuropathy res56: Type 2 Diabetes diagnostic Read
C109B00 Non-insulin dependent diabetes mellitus with polyneuropathy res56: Type 2 Diabetes diagnostic Read
C109B11 Type II diabetes mellitus with polyneuropathy res56: Type 2 Diabetes diagnostic Read
C109B12 Type 2 diabetes mellitus with polyneuropathy res56: Type 2 Diabetes diagnostic Read
C109C00 Non-insulin dependent diabetes mellitus with nephropathy res56: Type 2 Diabetes diagnostic Read
C109C11 Type II diabetes mellitus with nephropathy res56: Type 2 Diabetes diagnostic Read
C109C12 Type 2 diabetes mellitus with nephropathy res56: Type 2 Diabetes diagnostic Read
C109D00 Non-insulin dependent diabetes mellitus with hypoglyca coma res56: Type 2 Diabetes diagnostic Read
C109D11 Type II diabetes mellitus with hypoglycaemic coma res56: Type 2 Diabetes diagnostic Read
C109D12 Type 2 diabetes mellitus with hypoglycaemic coma res56: Type 2 Diabetes diagnostic Read
C109E00 Non-insulin depend diabetes mellitus with diabetic cataract res56: Type 2 Diabetes diagnostic Read
C109E11 Type II diabetes mellitus with diabetic cataract res56: Type 2 Diabetes diagnostic Read
C109E12 Type 2 diabetes mellitus with diabetic cataract res56: Type 2 Diabetes diagnostic Read
C109F11 Type II diabetes mellitus with peripheral angiopathy res56: Type 2 Diabetes diagnostic Read
C109F12 Type 2 diabetes mellitus with peripheral angiopathy res56: Type 2 Diabetes diagnostic Read
C109G00 Non-insulin dependent diabetes mellitus with arthropathy res56: Type 2 Diabetes diagnostic Read
C109G11 Type II diabetes mellitus with arthropathy res56: Type 2 Diabetes diagnostic Read
C109G12 Type 2 diabetes mellitus with arthropathy res56: Type 2 Diabetes diagnostic Read
C109H11 Type II diabetes mellitus with neuropathic arthropathy res56: Type 2 Diabetes diagnostic Read
C109H12 Type 2 diabetes mellitus with neuropathic arthropathy res56: Type 2 Diabetes diagnostic Read
C109J00 Insulin treated Type 2 diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C109J11 Insulin treated non-insulin dependent diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C109J12 Insulin treated Type II diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C109K00 Hyperosmolar non-ketotic state in type 2 diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C10F.00 Type 2 diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C10F.11 Type II diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C10F000 Type 2 diabetes mellitus with renal complications res56: Type 2 Diabetes diagnostic Read
C10F011 Type II diabetes mellitus with renal complications res56: Type 2 Diabetes diagnostic Read
C10F100 Type 2 diabetes mellitus with ophthalmic complications res56: Type 2 Diabetes diagnostic Read
C10F111 Type II diabetes mellitus with ophthalmic complications res56: Type 2 Diabetes diagnostic Read
C10F200 Type 2 diabetes mellitus with neurological complications res56: Type 2 Diabetes diagnostic Read
C10F211 Type II diabetes mellitus with neurological complications res56: Type 2 Diabetes diagnostic Read
C10F300 Type 2 diabetes mellitus with multiple complications res56: Type 2 Diabetes diagnostic Read
C10F311 Type II diabetes mellitus with multiple complications res56: Type 2 Diabetes diagnostic Read
C10F400 Type 2 diabetes mellitus with ulcer res56: Type 2 Diabetes diagnostic Read
C10F411 Type II diabetes mellitus with ulcer res56: Type 2 Diabetes diagnostic Read
C10F500 Type 2 diabetes mellitus with gangrene res56: Type 2 Diabetes diagnostic Read
C10F511 Type II diabetes mellitus with gangrene res56: Type 2 Diabetes diagnostic Read
C10F600 Type 2 diabetes mellitus with retinopathy res56: Type 2 Diabetes diagnostic Read
C10F611 Type II diabetes mellitus with retinopathy res56: Type 2 Diabetes diagnostic Read
C10F700 Type 2 diabetes mellitus - poor control res56: Type 2 Diabetes diagnostic Read
C10F711 Type II diabetes mellitus - poor control res56: Type 2 Diabetes diagnostic Read
C10F900 Type 2 diabetes mellitus without complication res56: Type 2 Diabetes diagnostic Read
C10F911 Type II diabetes mellitus without complication res56: Type 2 Diabetes diagnostic Read
C10FA00 Type 2 diabetes mellitus with mononeuropathy res56: Type 2 Diabetes diagnostic Read
C10FA11 Type II diabetes mellitus with mononeuropathy res56: Type 2 Diabetes diagnostic Read
C10FB00 Type 2 diabetes mellitus with polyneuropathy res56: Type 2 Diabetes diagnostic Read
C10FB11 Type II diabetes mellitus with polyneuropathy res56: Type 2 Diabetes diagnostic Read
C10FC00 Type 2 diabetes mellitus with nephropathy res56: Type 2 Diabetes diagnostic Read
C10FC11 Type II diabetes mellitus with nephropathy res56: Type 2 Diabetes diagnostic Read
C10FD00 Type 2 diabetes mellitus with hypoglycaemic coma res56: Type 2 Diabetes diagnostic Read
C10FD11 Type II diabetes mellitus with hypoglycaemic coma res56: Type 2 Diabetes diagnostic Read
C10FE00 Type 2 diabetes mellitus with diabetic cataract res56: Type 2 Diabetes diagnostic Read
C10FE11 Type II diabetes mellitus with diabetic cataract res56: Type 2 Diabetes diagnostic Read
C10FF00 Type 2 diabetes mellitus with peripheral angiopathy res56: Type 2 Diabetes diagnostic Read
C10FF11 Type II diabetes mellitus with peripheral angiopathy res56: Type 2 Diabetes diagnostic Read
C10FG11 Type II diabetes mellitus with arthropathy res56: Type 2 Diabetes diagnostic Read
C10FH00 Type 2 diabetes mellitus with neuropathic arthropathy res56: Type 2 Diabetes diagnostic Read
C10FH11 Type II diabetes mellitus with neuropathic arthropathy res56: Type 2 Diabetes diagnostic Read
C10FJ00 Insulin treated Type 2 diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C10FJ11 Insulin treated Type II diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C10FK00 Hyperosmolar non-ketotic state in type 2 diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C10FK11 Hyperosmolar non-ketotic state in type II diabetes mellitus res56: Type 2 Diabetes diagnostic Read
C10FL00 Type 2 diabetes mellitus with persistent proteinuria res56: Type 2 Diabetes diagnostic Read
C10FL11 Type II diabetes mellitus with persistent proteinuria res56: Type 2 Diabetes diagnostic Read
C10FM00 Type 2 diabetes mellitus with persistent microalbuminuria res56: Type 2 Diabetes diagnostic Read
C10FM11 Type II diabetes mellitus with persistent microalbuminuria res56: Type 2 Diabetes diagnostic Read
C10FN00 Type 2 diabetes mellitus with ketoacidosis res56: Type 2 Diabetes diagnostic Read
C10FN11 Type II diabetes mellitus with ketoacidosis res56: Type 2 Diabetes diagnostic Read
C10FP00 Type 2 diabetes mellitus with ketoacidotic coma res56: Type 2 Diabetes diagnostic Read
C10FQ00 Type 2 diabetes mellitus with exudative maculopathy res56: Type 2 Diabetes diagnostic Read
C10FR00 Type 2 diabetes mellitus with gastroparesis res56: Type 2 Diabetes diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH718/version/1436/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH718/version/1436/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH718', '1436', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH718/version/1436/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH718/version/1436/export/codes/?format=json
CSV site_root/phenotypes/PH718/version/1436/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH718', '1436', api_client=client)

Version History

Version
ID
Name Owner Publish date
1436 Type 2 Diabetes ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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