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Calcium Blockers

Victor W Zhong, Juhaeri Juhaeri, Stephen R Cole, Christian M Shay, Carolyn A Chew-Graham, Penny Gordon-Larsen, Evangelos Kontopantelis, Elizabeth J Mayer-Davis

Type
Drug
ID
PH724
Version ID
1448
Data Sources
Valid event data range
01/04/1997 - 31/03/2014
Sex
Female, Male
Agreement Date
2017-10-23
Coding system
GPRD product codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Aims:

To determine association between HbA1C variability and hypoglycemia requiring hospitalization (HH) in adults with type 1 diabetes (T1D) and type 2 diabetes (T2D).

Methods:

Using nested case-control design in electronic health record data in England, one case with first or recurrent HH was matched to one control who had not experienced HH in incident T1D and T2D adults. HbA1C variability was determined by standard deviation of ≥3 HbA1C results. Conditional logistic models were applied to determine association of HbA1C variability with first and recurrent HH.

Results:

In T1D, every 1.0% increase in HbA1C variability was associated with 90% higher first HH risk (95% CI, 1.25–2.89) and 392% higher recurrent HH risk (95% CI, 1.17–20.61). In T2D, a 1.0% increase in HbA1C variability was associated with 556% higher first HH risk (95% CI, 3.88–11.08) and 573% higher recurrent HH risk (95% CI,1.59–28.51). In T2D for first HH, the association was the strongest in non-insulin non-sulfonylurea users (P b 0.0001); for recurrent HH, the association was stronger in insulin users than sulfonylurea users (P = 0.07). The HbA1C variability-HH association was stronger in more recent years in T2D (P ≤ 0.004).

Conclusions:

HbA1C variability is a strong predictor for HH in T1D and T2D.

Publications

  • Victor W Zhong, Juhaeri Juhaeri, Stephen R Cole, Christian M Shay, Carolyn A Chew-Graham, Penny Gordon-Larsen, Evangelos Kontopantelis, Elizabeth J Mayer-Davis, HbA1C variability and hypoglycemia hospitalization in adults with type 1 and type 2 diabetes: A nested case-control study. Journal of Diabetes and Its Complications, 32(2), 2017.

Clinical Code List

Rows: 549
Code Description Coding System (CPRD_product_code) Entity type Category
10135 Nifedipress mr 10mg Modified-release tablet (Sandoz Ltd) CPRD_product_code res50: calcium blockers drug
10136 Nifedipress MR 20 tablets (Dexcel-Pharma Ltd) CPRD_product_code res50: calcium blockers drug
10153 Felendil xl 5mg Modified-release tablet (Ratiopharm UK Ltd) CPRD_product_code res50: calcium blockers drug
10246 Adipine XL 60mg tablets (Chiesi Ltd) CPRD_product_code res50: calcium blockers drug
10267 Adizem-XL 200mg capsules (Napp Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
10595 Nimotop 30mg tablets (Bayer Plc) CPRD_product_code res50: calcium blockers drug
10688 Verapamil 160mg tablets CPRD_product_code res50: calcium blockers drug
10832 Securon 80mg Tablet (Abbott Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
1118 Verapamil 40mg tablets CPRD_product_code res50: calcium blockers drug
1120 Verapamil 80mg tablets CPRD_product_code res50: calcium blockers drug
11223 Angitil SR 90 capsules (Chiesi Ltd) CPRD_product_code res50: calcium blockers drug
1130 Viazem XL 300mg capsules (Thornton & Ross Ltd) CPRD_product_code res50: calcium blockers drug
11512 Nifedipress MR 10 tablets (Dexcel-Pharma Ltd) CPRD_product_code res50: calcium blockers drug
11547 Nimodipine 30mg tablets CPRD_product_code res50: calcium blockers drug
11567 Ramipril 5mg with felodipine 5mg modified-release tablet CPRD_product_code res50: calcium blockers drug
11769 Calchan MR 20 tablets (Ranbaxy (UK) Ltd) CPRD_product_code res50: calcium blockers drug
11770 Dilzem SR 60 capsules (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
11777 Verapamil 40mg/5ml oral solution sugar free CPRD_product_code res50: calcium blockers drug
11922 Diltiazem 60mg/5ml oral suspension CPRD_product_code res50: calcium blockers drug
11943 Cardene 20mg capsules (Astellas Pharma Ltd) CPRD_product_code res50: calcium blockers drug
11965 Ramipril 2.5mg with felodipine 2.5mg modified-release tablet CPRD_product_code res50: calcium blockers drug
11966 Motens 2mg tablets (GlaxoSmithKline UK Ltd) CPRD_product_code res50: calcium blockers drug
11972 Vertab SR 240 tablets (Chiesi Ltd) CPRD_product_code res50: calcium blockers drug
11973 Calcicard CR 120mg tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
12104 Cordilox 160mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
12392 Univer 180mg modified-release capsules (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
12606 Nifelease 20mg Modified-release tablet (Eastern Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
12613 Unipine xl 30mg Modified-release tablet (Genus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
1262 Nifedipine 12 20mg Modified-release tablet CPRD_product_code res50: calcium blockers drug
12639 Diltiazem HCl 90mg Modified-release tablet (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
12705 Angiozem CR 90mg tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
12875 Cardene SR 45mg capsules (Astellas Pharma Ltd) CPRD_product_code res50: calcium blockers drug
1289 Tildiem Retard 120mg tablets (Sanofi) CPRD_product_code res50: calcium blockers drug
1298 Verapamil 240mg modified-release tablets CPRD_product_code res50: calcium blockers drug
1300 Nifensar xl 20mg Modified-release tablet (Rhone-Poulenc Rorer Ltd) CPRD_product_code res50: calcium blockers drug
13027 Viazem XL 240mg capsules (Thornton & Ross Ltd) CPRD_product_code res50: calcium blockers drug
13033 Angitil XL 240 capsules (Chiesi Ltd) CPRD_product_code res50: calcium blockers drug
13075 Dilzem XL 180 capsules (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
13127 Dilzem XL 240 capsules (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
13139 Adipine XL 30mg tablets (Chiesi Ltd) CPRD_product_code res50: calcium blockers drug
13240 Dilzem XL 120 capsules (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
13243 Lercanidipine 20mg tablets CPRD_product_code res50: calcium blockers drug
13251 Vera-Til SR 240mg tablets (Tillomed Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
13302 Dilzem SR 90 capsules (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
13410 Angiozem 60mg modified-release tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
13672 Angiopine MR 10mg tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
13699 Angiopine la 40mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
13856 Verapress MR 240mg tablets (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
13926 Diltiazem 360mg modified-release capsules CPRD_product_code res50: calcium blockers drug
13965 Cordilox MR 240mg tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
14300 Zanidip 20mg tablets (Recordati Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
14305 Vascalpha 10mg modified-release tablets (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
1449 Nifedipine 24 30mg Modified-release tablet CPRD_product_code res50: calcium blockers drug
14861 Calchan MR 10 tablets (Ranbaxy (UK) Ltd) CPRD_product_code res50: calcium blockers drug
14892 Anoheal 2% Cream (S.L.A. Pharma (UK) Ltd) CPRD_product_code res50: calcium blockers drug
15117 Nifedipine with atenolol 20mg + 50mg Capsule CPRD_product_code res50: calcium blockers drug
15221 Dilcardia xl 180mg Modified-release capsule (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
15288 Angitil XL 300 capsules (Chiesi Ltd) CPRD_product_code res50: calcium blockers drug
1529 Posicor 50mg Tablet (Roche Products Ltd) CPRD_product_code res50: calcium blockers drug
1538 Diltiazem 60mg tablets CPRD_product_code res50: calcium blockers drug
15652 Mibefradil 50mg Tablet CPRD_product_code res50: calcium blockers drug
15715 Genalat retard 20mg Modified-release tablet (Wyeth Pharmaceuticals) CPRD_product_code res50: calcium blockers drug
1574 Verapamil 120mg modified-release capsules CPRD_product_code res50: calcium blockers drug
16038 Dilzem SR 120 capsules (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
16073 Nifedipress MR 10 tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
16162 Amlodipine 5mg/5ml oral suspension CPRD_product_code res50: calcium blockers drug
16328 Verapress MR 240mg tablets (Dexcel-Pharma Ltd) CPRD_product_code res50: calcium blockers drug
16677 Cordilox 80mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
1684 Beta-Adalat modified-release capsules (Bayer Plc) CPRD_product_code res50: calcium blockers drug
16850 Angiozem CR 120mg tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
1686 Diltiazem 90mg modified-release capsules CPRD_product_code res50: calcium blockers drug
17006 Triapin 5mg/5mg modified-release tablets (Sanofi) CPRD_product_code res50: calcium blockers drug
17325 Cardilate MR 10mg tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
17338 Nifedotard 20 mr 20mg Modified-release tablet (Galen Ltd) CPRD_product_code res50: calcium blockers drug
17342 Nivaten retard 10mg Modified-release tablet (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
17406 Zemtard 180 XL capsules (Galen Ltd) CPRD_product_code res50: calcium blockers drug
17425 Zemtard 120 XL capsules (Galen Ltd) CPRD_product_code res50: calcium blockers drug
17448 Nifedipress mr 10mg Modified-release tablet (Sterwin Medicines) CPRD_product_code res50: calcium blockers drug
1747 Verapamil 120mg tablets CPRD_product_code res50: calcium blockers drug
17474 Felodipine 5mg modified-release / Ramipril 5mg tablets CPRD_product_code res50: calcium blockers drug
1748 Cordilox 120mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
17492 Zemtard 300 XL capsules (Galen Ltd) CPRD_product_code res50: calcium blockers drug
17557 Felotens XL 5mg tablets (Thornton & Ross Ltd) CPRD_product_code res50: calcium blockers drug
17566 Felotens XL 10mg tablets (Thornton & Ross Ltd) CPRD_product_code res50: calcium blockers drug
17586 Slozem 300mg capsules (Merck Serono Ltd) CPRD_product_code res50: calcium blockers drug
17599 Verapress MR 240mg tablets (Sandoz Ltd) CPRD_product_code res50: calcium blockers drug
17640 Amlostin 5mg tablets (Discovery Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
17666 Viazem XL 180mg capsules (Thornton & Ross Ltd) CPRD_product_code res50: calcium blockers drug
18038 Nisoldipine 20mg modified-release tablets CPRD_product_code res50: calcium blockers drug
18223 Trandolapril with verapamil 2mg + 180mg Modified-release capsule CPRD_product_code res50: calcium blockers drug
1836 Diltiazem 60mg modified-release tablets CPRD_product_code res50: calcium blockers drug
18379 Dilcardia SR 90mg capsules (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
18403 Diltiazem HCl 180mg Modified-release capsule (Hillcross Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
18404 Diltiazem 60mg modified-release capsules (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
1854 Adalat la 30mg Tablet (Bayer Plc) CPRD_product_code res50: calcium blockers drug
18606 Diltiazem and hydrochlorothiazide 150mg+12.5mg modified-release capsules CPRD_product_code res50: calcium blockers drug
18830 Disogram SR 90mg capsules (Ranbaxy (UK) Ltd) CPRD_product_code res50: calcium blockers drug
18834 Disogram SR 60mg capsules (Ranbaxy (UK) Ltd) CPRD_product_code res50: calcium blockers drug
18852 Disogram SR 120mg capsules (Ranbaxy (UK) Ltd) CPRD_product_code res50: calcium blockers drug
18874 Disogram SR 180mg capsules (Ranbaxy (UK) Ltd) CPRD_product_code res50: calcium blockers drug
18975 Calcicard 60mg Tablet (3M Health Care Ltd) CPRD_product_code res50: calcium blockers drug
19013 Clinium 120mg Tablet (LEO Pharma) CPRD_product_code res50: calcium blockers drug
19129 Syscor MR 10 tablets (Forest Laboratories UK Ltd) CPRD_product_code res50: calcium blockers drug
19170 Tensipine MR 10 tablets (Thornton & Ross Ltd) CPRD_product_code res50: calcium blockers drug
19175 Verapamil 40mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
19325 Cordilox 2.5mg/ml Injection (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
19426 Disogram SR 240mg capsules (Ranbaxy (UK) Ltd) CPRD_product_code res50: calcium blockers drug
19440 Disogram SR 300mg capsules (Ranbaxy (UK) Ltd) CPRD_product_code res50: calcium blockers drug
19457 Ranvera MR 240mg tablets (Ranbaxy (UK) Ltd) CPRD_product_code res50: calcium blockers drug
19459 Verapamil 240mg modified-release tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
19690 Verapamil 180mg modified-release / Trandolapril 2mg capsules CPRD_product_code res50: calcium blockers drug
1995 Diltiazem 12hr 120mg modified-release capsules CPRD_product_code res50: calcium blockers drug
20257 Cardilate MR 20mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
20311 Nifedipress mr 20mg Modified-release tablet (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
20459 Felendil xl 10mg Modified-release tablet (Ratiopharm UK Ltd) CPRD_product_code res50: calcium blockers drug
20579 Tarka modified-release capsules (Abbott Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
20591 Nifedipress MR 20 tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
20642 Bi-carzem sr 60mg Modified-release capsule (Tillomed Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
20878 Angiopine 10 capsules (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
20890 Zemtard 240 XL capsules (Galen Ltd) CPRD_product_code res50: calcium blockers drug
21145 Dilcardia SR 60mg capsules (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
21162 Felodipine 2.5mg modified-release / Ramipril 2.5mg tablets CPRD_product_code res50: calcium blockers drug
21216 Hypolar Retard 10mg tablets (Sandoz Ltd) CPRD_product_code res50: calcium blockers drug
21245 Nifedipress mr 10mg Modified-release tablet (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
21763 Diltiazem 60mg modified-release tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
21773 Diltiazem HCl 60mg Tablet (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
21778 Diltiazem 60mg modified-release tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
21795 Retalzem 60 modified-release tablets (Kent Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
21872 Angiopine 5mg Capsule (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
21886 Nifedipress MR 20 tablets (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
219 Diltiazem 120mg modified-release tablets CPRD_product_code res50: calcium blockers drug
21918 Optil 60mg modified-release tablets (Opus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
22019 Calanif 10mg Capsule (Berk Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
22142 Calcilat 10mg Capsule (Eastern Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
22217 Nimodrel 10mg modified-release tablet (Opus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
22241 Mibefradil 100mg Tablet CPRD_product_code res50: calcium blockers drug
22619 Britiazim 60mg Modified-release tablet (Thames Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
22696 Slofedipine 20mg tablets (Sterwin Medicines) CPRD_product_code res50: calcium blockers drug
2280 Adalat retard 10mg tablets (Bayer Plc) CPRD_product_code res50: calcium blockers drug
22826 Securon 160mg Tablet (Abbott Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
23233 Bi-carzem sr 90mg Modified-release capsule (Tillomed Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
2343 Adalat retard 20mg tablets (Bayer Plc) CPRD_product_code res50: calcium blockers drug
23505 Adizem xl plus 150mg+12.5mg Modified-release capsule (Napp Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
23733 Optil sr 90mg Modified-release capsule (Opus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
23736 Hypolar XL 30 tablets (Sandoz Ltd) CPRD_product_code res50: calcium blockers drug
23805 Nisoldipine 10mg modified-release tablets CPRD_product_code res50: calcium blockers drug
23823 Nisoldipine 30mg modified-release tablets CPRD_product_code res50: calcium blockers drug
23872 Berkatens 40mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
24228 Nimodrel 20mg modified-release tablet (Opus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
24365 Cardioplen XL 5mg tablets (Chiesi Ltd) CPRD_product_code res50: calcium blockers drug
24366 Cardioplen XL 10mg tablets (Chiesi Ltd) CPRD_product_code res50: calcium blockers drug
2453 Diltiazem 60mg modified-release capsules CPRD_product_code res50: calcium blockers drug
25059 Berkatens 80mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
25132 Nifopress MR 20mg tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
2521 Adalat 10mg capsules (Bayer Plc) CPRD_product_code res50: calcium blockers drug
2528 Slozem 120mg capsules (Merck Serono Ltd) CPRD_product_code res50: calcium blockers drug
25572 Felogen XL 5mg tablets (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
25646 Nivaten retard 20mg Modified-release tablet (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
25777 Dilcardia SR 120mg capsules (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
25919 Nifedipine 20mg modified-release tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
2592 Viazem XL 120mg capsules (Thornton & Ross Ltd) CPRD_product_code res50: calcium blockers drug
2605 Nifedipine 10mg modified-release capsules CPRD_product_code res50: calcium blockers drug
26252 Berkatens 160mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
26265 Calanif 5mg Capsule (Berk Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
26267 Optil sr 120mg Modified-release capsule (Opus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
26269 Optil sr 180mg Modified-release capsule (Opus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
26270 Optil xl 300mg Modified-release capsule (Opus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
26309 Optil xl 240mg Modified-release capsule (Opus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
26337 Cabren 10mg modified-release tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
26460 Dilcardia xl 240mg Modified-release capsule (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
26463 Zemret xl 240mg Capsule (Neo Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
2663 Diltiazem 240mg modified-release capsules CPRD_product_code res50: calcium blockers drug
26674 Verapamil 5mg/2ml solution for injection ampoules CPRD_product_code res50: calcium blockers drug
26759 Zildil SR 60mg capsules (Chanelle Medical UK Ltd) CPRD_product_code res50: calcium blockers drug
26774 Nifedipine 10mg/5ml Oral suspension CPRD_product_code res50: calcium blockers drug
2686 Dilzem xl mr 240mg Modified-release capsule (Elan Pharma) CPRD_product_code res50: calcium blockers drug
269 Nifedipine 5mg capsules CPRD_product_code res50: calcium blockers drug
27135 Diltiazem sr 90mg Capsule (Hillcross Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
27136 Diltiazem 90mg modified-release tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
27295 Securon IV 5mg/2ml solution for injection ampoules (Abbott Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
27401 Kenzem SR 90mg capsules (Kent Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
2746 Coracten SR 10mg capsules (UCB Pharma Ltd) CPRD_product_code res50: calcium blockers drug
27685 Diltiazem HCl 300mg Capsule (PLIVA Pharma Ltd) CPRD_product_code res50: calcium blockers drug
2811 Adizem sr 180mg Modified-release capsule (Napp Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
28438 Triapin 2.5mg/2.5mg modified-release tablets (Sanofi) CPRD_product_code res50: calcium blockers drug
28688 Nifedipine 10mg modified-release tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
28721 Neofel XL 5mg tablets (Kent Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
28843 Verapamil hc 80mg Tablet (Celltech Pharma Europe Ltd) CPRD_product_code res50: calcium blockers drug
28844 Berkatens 120mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
2888 Tildiem 60mg modified-release tablets (Sanofi) CPRD_product_code res50: calcium blockers drug
28949 Bi-carzem sr 120mg Modified-release capsule (Tillomed Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
29 Amlodipine besilate 5mg tablets CPRD_product_code res50: calcium blockers drug
29044 Neofel XL 10mg tablets (Kent Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
29145 Felendil xl 2.5mg Modified-release tablet (Ratiopharm UK Ltd) CPRD_product_code res50: calcium blockers drug
2926 Nicardipine 20mg capsules CPRD_product_code res50: calcium blockers drug
29637 Verapress MR 240mg tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
29676 Calazem 60mg Modified-release tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
30197 Diltiazem 120mg modified-release capsules CPRD_product_code res50: calcium blockers drug
30199 Nifedipine 30mg modified-release tablets CPRD_product_code res50: calcium blockers drug
30242 Diltiazem 180mg modified-release capsules CPRD_product_code res50: calcium blockers drug
30462 Ethimil MR 240mg tablets (Genus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
30473 Coroday MR 20mg tablets (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
30557 Felogen XL 10mg tablets (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
3057 Securon 120mg tablets (Abbott Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
3061 Diltiazem 12hr 180mg modified-release capsules CPRD_product_code res50: calcium blockers drug
30758 Lidoflazine 120mg Tablet CPRD_product_code res50: calcium blockers drug
30915 Cabren 2.5mg modified-release tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
30991 Cabren 5mg modified-release tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
3118 Adizem sr 90mg Modified-release capsule (Napp Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
31336 Syscor MR 30 tablets (Forest Laboratories UK Ltd) CPRD_product_code res50: calcium blockers drug
31337 Syscor MR 20 tablets (Forest Laboratories UK Ltd) CPRD_product_code res50: calcium blockers drug
31489 Bi-carzem xl 240mg Capsule (Tillomed Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
31490 Zolvera 40mg/5ml oral solution (Rosemont Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
31676 Diltiazem HCl 120mg Modified-release tablet (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
31711 Verapamil 80mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
31737 Zildil SR 120mg capsules (Chanelle Medical UK Ltd) CPRD_product_code res50: calcium blockers drug
31761 Amlostin 10mg tablets (Discovery Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
32089 Diltiazem HCl 120mg Modified-release capsule (Hillcross Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
3221 Lacidipine 4mg tablets CPRD_product_code res50: calcium blockers drug
32262 Diltiazem HCl 60mg Tablet (C P Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
32590 Verapamil 40mg tablets (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
32595 Amlodipine 5mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
32658 Dilcardia xl 120mg Modified-release capsule (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
32870 Diltiazem 60mg modified-release tablets (Sterwin Medicines) CPRD_product_code res50: calcium blockers drug
32917 Amlodipine 5mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
32922 Felodipine 10mg Modified-release tablet (Sandoz Ltd) CPRD_product_code res50: calcium blockers drug
3302 Cardene SR 30mg capsules (Astellas Pharma Ltd) CPRD_product_code res50: calcium blockers drug
33025 Nimodrel XL 30mg tablets (Zurich Pharmaceuticals) CPRD_product_code res50: calcium blockers drug
33091 Felodipine 10mg modified-release tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
3342 Securon SR 240mg tablets (Abbott Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
3343 Half Securon SR 120mg tablets (Abbott Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
33471 Verapamil 40mg tablets (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
3370 Dilzem xl mr 120mg Modified-release capsule (Elan Pharma) CPRD_product_code res50: calcium blockers drug
33932 Parmid XL 5mg tablets (Sandoz Ltd) CPRD_product_code res50: calcium blockers drug
34093 Amlodipine 10mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
34101 Nifedipine mr 20mg Modified-release tablet (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
34115 Nifedipine 60mg Modified-release tablet CPRD_product_code res50: calcium blockers drug
34146 Nifedipine mr 10mg Modified-release tablet (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
34187 Nifedipine 10mg Modified-release tablet (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
34247 Nifedipine 10mg Capsule (Berk Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
34377 Diltiazem HCl 90mg Modified-release capsule (Hillcross Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
34475 Diltiazem HCl 90mg Modified-release tablet (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
34522 Nifedipine 5mg capsules (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
34581 Diltiazem HCl 60mg Modified-release tablet (Kent Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
34607 Nifedipine 5mg capsules (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
34824 Diltiazem HCl 120mg Modified-release tablet (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
34959 Verapamil 40mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
34975 Nifedipine 5mg capsules (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
35084 Vascalpha 5mg modified-release tablets (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
35096 Exforge 10mg/160mg tablets (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
35173 Valsartan 160mg with amlodipine 5mg tablets CPRD_product_code res50: calcium blockers drug
35174 Valsartan 80mg with amlodipine 5mg tablets CPRD_product_code res50: calcium blockers drug
35189 Amlodipine 10mg / Valsartan 160mg tablets CPRD_product_code res50: calcium blockers drug
35304 Valsartan 160mg with amlodipine 10mg tablets CPRD_product_code res50: calcium blockers drug
35317 Exforge 5mg/80mg tablets (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
35329 Amlodipine 5mg / Valsartan 80mg tablets CPRD_product_code res50: calcium blockers drug
35343 Amlodipine 5mg / Valsartan 160mg tablets CPRD_product_code res50: calcium blockers drug
35592 Cardioplen XL 2.5mg tablets (Chiesi Ltd) CPRD_product_code res50: calcium blockers drug
35646 Neozipine XL 60mg tablets (Kent Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
35696 Kenzem SR 120mg capsules (Kent Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
35697 Exforge 5mg/160mg tablets (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
35729 Verapamil 80mg tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
36202 Amlodipine 10mg tablets (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
36583 Zemret xl 180mg Capsule (Neo Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
36620 Parmid XL 10mg tablets (Sandoz Ltd) CPRD_product_code res50: calcium blockers drug
36664 Zemret xl 300mg Capsule (Neo Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
3676 Dilzem xl mr 180mg Modified-release capsule (Elan Pharma) CPRD_product_code res50: calcium blockers drug
37025 Nifedipine 20mg modified-release tablets CPRD_product_code res50: calcium blockers drug
3711 Adipine MR 20 tablets (Chiesi Ltd) CPRD_product_code res50: calcium blockers drug
3712 Coracten XL 30mg capsules (UCB Pharma Ltd) CPRD_product_code res50: calcium blockers drug
37184 Valni XL 30mg tablets (Zentiva) CPRD_product_code res50: calcium blockers drug
37530 Neozipine XL 30mg tablets (Kent Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
37726 Nifedipine 100mg/5ml oral suspension CPRD_product_code res50: calcium blockers drug
37774 Kenzem SR 60mg capsules (Kent Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
37897 Felotens XL 2.5mg tablets (Thornton & Ross Ltd) CPRD_product_code res50: calcium blockers drug
38066 Diltiazem HCl 60mg Modified-release tablet (Lagap) CPRD_product_code res50: calcium blockers drug
38107 Nifedipine sr 30mg Tablet (Hillcross Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
38434 Keloc SR 10mg tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
38545 Tildiem LA 200 capsules (Sanofi) CPRD_product_code res50: calcium blockers drug
38632 Adizem-SR 90mg capsules (Napp Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
38634 Adizem-XL 300mg capsules (Napp Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
38818 Adizem-SR 120mg capsules (Napp Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
38831 Adizem-SR 180mg capsules (Napp Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
38855 Adizem-XL 180mg capsules (Napp Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
38865 Adizem-XL 120mg capsules (Napp Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
38876 Tildiem LA 300 capsules (Sanofi) CPRD_product_code res50: calcium blockers drug
38882 Adizem-XL 240mg capsules (Napp Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
38964 Adizem-SR 120mg tablets (Napp Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
39009 Verapamil 40mg tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
3917 Istin 5mg tablets (Pfizer Ltd) CPRD_product_code res50: calcium blockers drug
39171 Bi-Carzem SR 60mg capsules (Tillomed Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
39298 Bi-Carzem SR 90mg capsules (Tillomed Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
3930 Nifedipine 60mg modified-release tablets CPRD_product_code res50: calcium blockers drug
3931 Posicor 100mg Tablet (Roche Products Ltd) CPRD_product_code res50: calcium blockers drug
39357 Neofel XL 2.5mg tablets (Kent Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
3943 Verapamil 240mg modified-release capsules CPRD_product_code res50: calcium blockers drug
39800 Valni XL 60mg tablets (Zentiva) CPRD_product_code res50: calcium blockers drug
39804 Amlodipine 5mg tablets (Dr Reddy's Laboratories (UK) Ltd) CPRD_product_code res50: calcium blockers drug
39914 Amlodipine 5mg tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
39984 Sevikar 20mg/5mg tablets (Daiichi Sankyo UK Ltd) CPRD_product_code res50: calcium blockers drug
40074 Nifedipine 20mg Capsule CPRD_product_code res50: calcium blockers drug
40316 Olmesartan medoxomil 20mg / Amlodipine 5mg tablets CPRD_product_code res50: calcium blockers drug
40405 Verapamil 120mg tablets (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
40633 Vascalpha 5mg modified-release tablets (Almus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
40639 Olmesartan medoxomil 40mg / Amlodipine 5mg tablets CPRD_product_code res50: calcium blockers drug
40668 Olmesartan medoxomil 40mg / Amlodipine 10mg tablets CPRD_product_code res50: calcium blockers drug
410 Nifedipine 10mg modified-release tablets CPRD_product_code res50: calcium blockers drug
41203 Sevikar 40mg/10mg tablets (Daiichi Sankyo UK Ltd) CPRD_product_code res50: calcium blockers drug
41205 Sevikar 40mg/5mg tablets (Daiichi Sankyo UK Ltd) CPRD_product_code res50: calcium blockers drug
41489 Bi-Carzem SR 120mg capsules (Tillomed Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
41586 Verapamil 80mg tablets (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
41635 Diltiazem 60mg modified-release tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
41679 Verapamil 80mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: calcium blockers drug
41693 Verapamil 120mg tablets (Generics (UK) Ltd) CPRD_product_code res50: calcium blockers drug
41979 Adipine la 30mg Modified-release tablet (Chiesi Ltd) CPRD_product_code res50: calcium blockers drug
42210 Amlodipine 10mg tablets (Zentiva) CPRD_product_code res50: calcium blockers drug
4227 Adalat la 60mg Tablet (Bayer Plc) CPRD_product_code res50: calcium blockers drug
4239 Adipine MR 10 tablets (Chiesi Ltd) CPRD_product_code res50: calcium blockers drug
42625 Vera-Til SR 120mg tablets (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
42731 Diltiazem sr 120mg Capsule (Hillcross Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
42804 Diltiazem HCl 180mg Capsule (PLIVA Pharma Ltd) CPRD_product_code res50: calcium blockers drug
42819 Diltiazem xl 240mg Capsule (Hillcross Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
42912 Nifedipine 10mg capsules (Teva UK Ltd) CPRD_product_code res50: calcium blockers drug
4308 Dilzem sr 90mg Capsule (Elan Pharma) CPRD_product_code res50: calcium blockers drug
43222 Valni 20 Retard tablets (Tillomed Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
43394 Pinefeld XL 10mg tablets (Tillomed Laboratories Ltd) CPRD_product_code res50: calcium blockers drug
43410 Nifedipine extra 60mg Modified-release tablet CPRD_product_code res50: calcium blockers drug
43430 Diltiazem 120mg modified-release tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
43470 Amlodipine 5mg tablets (Wockhardt UK Ltd) CPRD_product_code res50: calcium blockers drug
43511 Nifedipine 10mg capsules (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
43512 Felodipine 5mg modified-release tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
43515 Nifedipine 10mg capsules (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
43753 Adalat LA 30 tablets (Bayer Plc) CPRD_product_code res50: calcium blockers drug
43790 Vascalpha 10mg modified-release tablets (Almus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
43818 Adalat LA 60 tablets (Bayer Plc) CPRD_product_code res50: calcium blockers drug
43879 Vera-Til SR 240mg tablets (Actavis UK Ltd) CPRD_product_code res50: calcium blockers drug
43880 Amlodipine 5mg tablets (Almus Pharmaceuticals Ltd) CPRD_product_code res50: calcium blockers drug
4408 Slozem 240mg capsules (Merck Serono Ltd) CPRD_product_code res50: calcium blockers drug
44192 Zemret 240 XL capsules (Tillomed Laboratories Ltd) CPRD_product_code