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Congestive Heart Disease

Victor W Zhong, Juhaeri Juhaeri, Stephen R Cole, Christian M Shay, Carolyn A Chew-Graham, Penny Gordon-Larsen, Evangelos Kontopantelis, Elizabeth J Mayer-Davis

Type
Disease or Syndrome
ID
PH727
Version ID
1454
Data Sources
Valid event data range
01/04/1997 - 31/03/2014
Sex
Female, Male
Agreement Date
2017-10-23
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Aims:

To determine association between HbA1C variability and hypoglycemia requiring hospitalization (HH) in adults with type 1 diabetes (T1D) and type 2 diabetes (T2D).

Methods: Using nested case-control design in electronic health record data in England, one case with first or recurrent HH was matched to one control who had not experienced HH in incident T1D and T2D adults. HbA1C variability was determined by standard deviation of ≥3 HbA1C results. Conditional logistic models were applied to determine association of HbA1C variability with first and recurrent HH.

Results:

In T1D, every 1.0% increase in HbA1C variability was associated with 90% higher first HH risk (95% CI,

1.25–2.89) and 392% higher recurrent HH risk (95% CI, 1.17–20.61). In T2D, a 1.0% increase in HbA1C variability was associated with 556% higher first HH risk (95% CI, 3.88–11.08) and 573% higher recurrent HH risk

(95% CI,1.59–28.51). In T2D for first HH, the association was the strongest in non-insulin non-sulfonylurea users (P b 0.0001); for recurrent HH, the association was stronger in insulin users than sulfonylurea users

(P = 0.07). The HbA1C variability-HH association was stronger in more recent years in T2D (P ≤ 0.004). Conclusions: HbA1C variability is a strong predictor for HH in T1D and T2D.

Publications

  • Victor W Zhong, Juhaeri Juhaeri, Stephen R Cole, Christian M Shay, Carolyn A Chew-Graham, Penny Gordon-Larsen, Evangelos Kontopantelis, Elizabeth J Mayer-Davis, HbA1C variability and hypoglycemia hospitalization in adults with type 1 and type 2 diabetes: A nested case-control study. Journal of Diabetes and Its Complications, 32(2), 2017.

Clinical Code List

Rows: 47
Code Description Entity type Category Coding System (Read)
14A6.00 H/O: heart failure res50: congestive heart disease diagnostic Read
14AM.00 H/O: Heart failure in last year res50: congestive heart disease diagnostic Read
1O1..00 Heart failure confirmed res50: congestive heart disease diagnostic Read
33BA.00 Impaired left ventricular function res50: congestive heart disease diagnostic Read
585f.00 Echocardiogram shows left ventricular systolic dysfunction res50: congestive heart disease diagnostic Read
585g.00 Echocardiogram shows left ventricular diastolic dysfunction res50: congestive heart disease diagnostic Read
585k.00 Echocardiogram shows normal left ventricular function res50: congestive heart disease diagnostic Read
8B29.00 Cardiac failure therapy res50: congestive heart disease diagnostic Read
8CL3.00 Heart failure care plan discussed with patient res50: congestive heart disease diagnostic Read
8CMK.00 Has heart failure management plan res50: congestive heart disease diagnostic Read
8CMW800 Heart failure clinical pathway res50: congestive heart disease diagnostic Read
8CeC.00 Preferred place of care for next exacerbation heart failure res50: congestive heart disease diagnostic Read
8H2S.00 Admit heart failure emergency res50: congestive heart disease diagnostic Read
G232.00 Hypertensive heart&renal dis wth (congestive) heart failure res50: congestive heart disease diagnostic Read
G234.00 Hyperten heart&renal dis+both(congestv)heart and renal fail res50: congestive heart disease diagnostic Read
G575.11 Cardio-respiratory arrest res50: congestive heart disease diagnostic Read
G575100 Sudden cardiac death, so described res50: congestive heart disease diagnostic Read
G58..00 Heart failure res50: congestive heart disease diagnostic Read
G58..11 Cardiac failure res50: congestive heart disease diagnostic Read
G580.00 Congestive heart failure res50: congestive heart disease diagnostic Read
G580.11 Congestive cardiac failure res50: congestive heart disease diagnostic Read
G580.12 Right heart failure res50: congestive heart disease diagnostic Read
G580.13 Right ventricular failure res50: congestive heart disease diagnostic Read
G580.14 Biventricular failure res50: congestive heart disease diagnostic Read
G580000 Acute congestive heart failure res50: congestive heart disease diagnostic Read
G580100 Chronic congestive heart failure res50: congestive heart disease diagnostic Read
G580200 Decompensated cardiac failure res50: congestive heart disease diagnostic Read
G580300 Compensated cardiac failure res50: congestive heart disease diagnostic Read
G580400 Congestive heart failure due to valvular disease res50: congestive heart disease diagnostic Read
G581.00 Left ventricular failure res50: congestive heart disease diagnostic Read
G581.13 Impaired left ventricular function res50: congestive heart disease diagnostic Read
G581000 Acute left ventricular failure res50: congestive heart disease diagnostic Read
G582.00 Acute heart failure res50: congestive heart disease diagnostic Read
G583.00 Heart failure with normal ejection fraction res50: congestive heart disease diagnostic Read
G583.11 HFNEF - heart failure with normal ejection fraction res50: congestive heart disease diagnostic Read
G583.12 Heart failure with preserved ejection fraction res50: congestive heart disease diagnostic Read
G584.00 Right ventricular failure res50: congestive heart disease diagnostic Read
G58z.00 Heart failure NOS res50: congestive heart disease diagnostic Read
G58z.11 Weak heart res50: congestive heart disease diagnostic Read
G58z.12 Cardiac failure NOS res50: congestive heart disease diagnostic Read
G5y4z00 Post cardiac operation heart failure NOS res50: congestive heart disease diagnostic Read
G5yy900 Left ventricular systolic dysfunction res50: congestive heart disease diagnostic Read
G5yyA00 Left ventricular diastolic dysfunction res50: congestive heart disease diagnostic Read
Q48y100 Congenital cardiac failure res50: congestive heart disease diagnostic Read
Q490.00 Neonatal cardiac failure res50: congestive heart disease diagnostic Read
SP11100 Cardiac insufficiency as a complication of care res50: congestive heart disease diagnostic Read
SP11111 Heart failure as a complication of care res50: congestive heart disease diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH727/version/1454/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH727/version/1454/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH727', '1454', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH727/version/1454/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH727/version/1454/export/codes/?format=json
CSV site_root/phenotypes/PH727/version/1454/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH727', '1454', api_client=client)

Version History

Version
ID
Name Owner Publish date
1454 Congestive Heart Disease ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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