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Diuretics

Victor W Zhong, Juhaeri Juhaeri, Stephen R Cole, Christian M Shay, Carolyn A Chew-Graham, Penny Gordon-Larsen, Evangelos Kontopantelis, Elizabeth J Mayer-Davis

Type
Drug
ID
PH731
Version ID
1462
Data Sources
Valid event data range
01/04/1997 - 31/03/2014
Sex
Female, Male
Agreement Date
2017-10-23
Coding system
GPRD product codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Aims:

To determine association between HbA1C variability and hypoglycemia requiring hospitalization (HH) in adults with type 1 diabetes (T1D) and type 2 diabetes (T2D).

Methods:

Using nested case-control design in electronic health record data in England, one case with first or recurrent HH was matched to one control who had not experienced HH in incident T1D and T2D adults. HbA1C variability was determined by standard deviation of ≥3 HbA1C results. Conditional logistic models were applied to determine association of HbA1C variability with first and recurrent HH.

Results:

In T1D, every 1.0% increase in HbA1C variability was associated with 90% higher first HH risk (95% CI, 1.25–2.89) and 392% higher recurrent HH risk (95% CI, 1.17–20.61). In T2D, a 1.0% increase in HbA1C variability was associated with 556% higher first HH risk (95% CI, 3.88–11.08) and 573% higher recurrent HH risk (95% CI,1.59–28.51). In T2D for first HH, the association was the strongest in non-insulin non-sulfonylurea users (P b 0.0001); for recurrent HH, the association was stronger in insulin users than sulfonylurea users (P = 0.07). The HbA1C variability-HH association was stronger in more recent years in T2D (P ≤ 0.004).

Conclusions:

HbA1C variability is a strong predictor for HH in T1D and T2D.

Publications

  • Victor W Zhong, Juhaeri Juhaeri, Stephen R Cole, Christian M Shay, Carolyn A Chew-Graham, Penny Gordon-Larsen, Evangelos Kontopantelis, Elizabeth J Mayer-Davis, HbA1C variability and hypoglycemia hospitalization in adults with type 1 and type 2 diabetes: A nested case-control study. Journal of Diabetes and Its Complications, 32(2), 2017.

Clinical Code List

Rows: 589
Code Description Coding System (CPRD_product_code) Entity type Category
10066 Torem 5mg tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
1021 Innozide 20mg/12.5mg tablets (Merck Sharp & Dohme Ltd) CPRD_product_code res50: diuretics drug
10214 Spironolactone 5mg/5ml oral suspension sugar free CPRD_product_code res50: diuretics drug
10251 Eplerenone 25mg tablets CPRD_product_code res50: diuretics drug
10316 CoAprovel 150mg/12.5mg tablets (Sanofi) CPRD_product_code res50: diuretics drug
10323 Losartan 100mg / Hydrochlorothiazide 25mg tablets CPRD_product_code res50: diuretics drug
10392 Lasix 500mg tablets (Sanofi) CPRD_product_code res50: diuretics drug
10422 Lasix 50mg/5ml Injection (Hoechst UK Ltd) CPRD_product_code res50: diuretics drug
1060 Amiloride 5mg tablets CPRD_product_code res50: diuretics drug
10627 Co-Betaloc tablets (Pfizer Ltd) CPRD_product_code res50: diuretics drug
10781 Lasix with k Tablet (Hoechst Marion Roussel) CPRD_product_code res50: diuretics drug
10902 Captopril 50mg with Hydrochlorothiazide 25mg tablets CPRD_product_code res50: diuretics drug
11133 Hydrochlorothiazide with captopril 25mg with 50mg Tablet CPRD_product_code res50: diuretics drug
11156 Spirolone 25mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
1124 Tenoretic 100mg/25mg tablets (AstraZeneca UK Ltd) CPRD_product_code res50: diuretics drug
1125 Navidrex -k Tablet (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
11265 Triamterene 50mg / Furosemide 40mg tablets CPRD_product_code res50: diuretics drug
11268 Torem 2.5mg tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
11338 Bendroflumethiazide 5mg with Nadolol 40mg tablets CPRD_product_code res50: diuretics drug
11351 Co-zidocapt 25mg/50mg tablets CPRD_product_code res50: diuretics drug
11384 Co-flumactone 50mg/50mg tablets CPRD_product_code res50: diuretics drug
11448 Irbesartan 150mg / Hydrochlorothiazide 12.5mg tablets CPRD_product_code res50: diuretics drug
11469 Irbesartan 300mg / Hydrochlorothiazide 12.5mg tablets CPRD_product_code res50: diuretics drug
11487 Torasemide 2.5mg tablets CPRD_product_code res50: diuretics drug
11519 Spironolactone 25mg/5ml oral suspension sugar free CPRD_product_code res50: diuretics drug
11526 CoAprovel 300mg/12.5mg tablets (Sanofi) CPRD_product_code res50: diuretics drug
11561 Co-zidocapt 12.5mg/25mg tablets CPRD_product_code res50: diuretics drug
11641 Captopril 25mg with Hydrochlorothiazide 12.5mg tablets CPRD_product_code res50: diuretics drug
1170 Cyclopenthiazide 500microgram tablets CPRD_product_code res50: diuretics drug
11864 Valsartan 160mg / Hydrochlorothiazide 12.5mg tablets CPRD_product_code res50: diuretics drug
12054 Propranolol 80mg / Bendroflumethiazide 2.5mg capsules CPRD_product_code res50: diuretics drug
1209 Neo-Naclex 5mg tablets (Mercury Pharma Group Ltd) CPRD_product_code res50: diuretics drug
1211 Bendroflumethiazide 2.5mg / Potassium chloride 630mg (potassium 8.4mmol) modified CPRD_product_code res50: diuretics drug
12110 Hydroflumethiazide 50mg Tablet CPRD_product_code res50: diuretics drug
1213 Neo-Naclex-K modified-release tablets (Mercury Pharma Group Ltd) CPRD_product_code res50: diuretics drug
12226 Burinex 1mg/5ml Oral solution (LEO Pharma) CPRD_product_code res50: diuretics drug
12294 Burinex 5mg tablets (LEO Pharma) CPRD_product_code res50: diuretics drug
12318 Lasix 250mg/25ml Injection (Hoechst Marion Roussel) CPRD_product_code res50: diuretics drug
12354 Etacrynic 50mg tablets CPRD_product_code res50: diuretics drug
12360 Nephril 1mg Tablet (Pfizer Ltd) CPRD_product_code res50: diuretics drug
12367 Piretanide 6mg capsule CPRD_product_code res50: diuretics drug
12440 Hydrosaluric 25mg tablets (Merck Sharp & Dohme Ltd) CPRD_product_code res50: diuretics drug
1251 Moduret 25 tablets (Merck Sharp & Dohme Ltd) CPRD_product_code res50: diuretics drug
12517 Timolol maleate with bendroflumethiazide 20mg + 5mg Tablet CPRD_product_code res50: diuretics drug
12546 Kalspare Tablet (Dominion Pharma) CPRD_product_code res50: diuretics drug
12547 Triamterene 50mg / Chlortalidone 50mg tablets CPRD_product_code res50: diuretics drug
12651 Timolol 10mg / Bendroflumethiazide 2.5mg tablets CPRD_product_code res50: diuretics drug
1288 Tenoret 50mg/12.5mg tablets (AstraZeneca UK Ltd) CPRD_product_code res50: diuretics drug
12926 Polythiazide 1mg tablets CPRD_product_code res50: diuretics drug
12946 Spironolactone 10mg/5ml oral suspension sugar free CPRD_product_code res50: diuretics drug
1297 Aldactide 50 tablets (Pfizer Ltd) CPRD_product_code res50: diuretics drug
1301 Frumil ls 20mg+2.5mg Tablet (Helios Healthcare Ltd) CPRD_product_code res50: diuretics drug
13246 Chlorothiazide 150mg/5ml oral suspension CPRD_product_code res50: diuretics drug
13264 Spironolactone 15mg/5ml oral suspension CPRD_product_code res50: diuretics drug
13352 Midamor 5mg Tablet (MSD Thomas Morson Pharmaceuticals) CPRD_product_code res50: diuretics drug
13363 Esidrex 50mg Tablet (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
13435 Frumil Forte 10mg/80mg tablets (Sanofi) CPRD_product_code res50: diuretics drug
13525 Hydrenox 50mg Tablet (Knoll Ltd) CPRD_product_code res50: diuretics drug
13526 Atenix Co 100 tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
1369 Furosemide with amiloride 40mg+5mg Tablet CPRD_product_code res50: diuretics drug
13871 Co-prenozide 160mg/0.25mg modified-release tablets CPRD_product_code res50: diuretics drug
14109 Spironolactone 100mg/5ml oral solution sugar free CPRD_product_code res50: diuretics drug
14126 Acebutolol 200mg / Hydrochlorothiazide 12.5mg tablets CPRD_product_code res50: diuretics drug
14144 Inspra 25mg tablets (Pfizer Ltd) CPRD_product_code res50: diuretics drug
14228 Coversyl Plus tablets (Servier Laboratories Ltd) CPRD_product_code res50: diuretics drug
14283 Valsartan 160mg / Hydrochlorothiazide 25mg tablets CPRD_product_code res50: diuretics drug
14438 Corgaretic 80mg tablets (Sanofi-Synthelabo Ltd) CPRD_product_code res50: diuretics drug
14587 Amiloride 5mg / Bumetanide 1mg tablets CPRD_product_code res50: diuretics drug
14738 Hydrochlorothiazide with losartan 12.5mg with 50mg Tablet CPRD_product_code res50: diuretics drug
14761 Frusid 40mg tablets (Dr Reddy's Laboratories (UK) Ltd) CPRD_product_code res50: diuretics drug
14837 Frusol 50mg/5ml oral solution (Rosemont Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
14870 Telmisartan 40mg / Hydrochlorothiazide 12.5mg tablets CPRD_product_code res50: diuretics drug
15031 Accuretic 12.5mg/10mg tablets (Pfizer Ltd) CPRD_product_code res50: diuretics drug
15052 Spiroctan 50mg Tablet (Roche Products Ltd) CPRD_product_code res50: diuretics drug
15108 Quinapril 10mg / Hydrochlorothiazide 12.5mg tablets CPRD_product_code res50: diuretics drug
15127 Hydrochlorothiazide with triamterene 25mgwith50mg Tablet CPRD_product_code res50: diuretics drug
15135 Hydrochlorothiazide with captopril 12.5mg with 25mg Tablet CPRD_product_code res50: diuretics drug
1520 Capozide 25mg/50mg tablets (Bristol-Myers Squibb Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
15341 Burinex 0.5mg/ml Injection (LEO Pharma) CPRD_product_code res50: diuretics drug
15457 Baycaron 25mg Tablet (Bayer Plc) CPRD_product_code res50: diuretics drug
15488 Metoprolol tartrate with chlortalidone Tablet CPRD_product_code res50: diuretics drug
15811 Co-flumactone 25mg/25mg tablets CPRD_product_code res50: diuretics drug
15874 Amiloride 2.5mg / furosemide 20mg tablets CPRD_product_code res50: diuretics drug
16060 Valsartan 80mg / Hydrochlorothiazide 12.5mg tablets CPRD_product_code res50: diuretics drug
16161 Telmisartan 80mg / Hydrochlorothiazide 12.5mg tablets CPRD_product_code res50: diuretics drug
16206 Froop 40mg tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
16498 Kalspare tablets (DHP Healthcare Ltd) CPRD_product_code res50: diuretics drug
16531 Eplerenone 50mg tablets CPRD_product_code res50: diuretics drug
16632 Hydrosaluric 50mg tablets (Merck Sharp & Dohme Ltd) CPRD_product_code res50: diuretics drug
16786 Chlortalidone 25mg with Atenolol 100mg tablets CPRD_product_code res50: diuretics drug
17143 Mefruside 25mg Tablet CPRD_product_code res50: diuretics drug
17149 Monozide 10 tablets (Wyeth Pharmaceuticals) CPRD_product_code res50: diuretics drug
1721 Dyazide 50mg/25mg tablets (AMCo) CPRD_product_code res50: diuretics drug
17252 Esidrex 25mg Tablet (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
17462 Bisoprolol 10mg / Hydrochlorothiazide 6.25mg tablets CPRD_product_code res50: diuretics drug
17561 Bendroflumethiazide 2.5mg / Potassium chloride 573mg (potassium 7.7mmol) modified CPRD_product_code res50: diuretics drug
17655 Carace 10 Tablet (Bristol-Myers Squibb Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
17689 MicardisPlus 80mg/12.5mg tablets (Boehringer Ingelheim Ltd) CPRD_product_code res50: diuretics drug
17720 Saluric 500mg Tablet (Merck Sharp & Dohme Ltd) CPRD_product_code res50: diuretics drug
1776 Burinex K modified-release tablets (LEO Pharma) CPRD_product_code res50: diuretics drug
1788 Atenolol 100mg with Chlortalidone 25mg tablets CPRD_product_code res50: diuretics drug
17902 Spirolone 100mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
17950 Spirolone 50mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
17960 Furosemide 20mg / Potassium chloride 750mg (potassium 10mmol) modified-release ta CPRD_product_code res50: diuretics drug
18096 Torasemide 10mg tablets CPRD_product_code res50: diuretics drug
18200 Olmesartan medoxomil 20mg / Hydrochlorothiazide 12.5mg tablets CPRD_product_code res50: diuretics drug
18202 MicardisPlus 40mg/12.5mg tablets (Boehringer Ingelheim Ltd) CPRD_product_code res50: diuretics drug
18263 Acezide 25mg/50mg tablets (Bristol-Myers Squibb Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
18267 Enduron 5mg Tablet (Abbott Laboratories Ltd) CPRD_product_code res50: diuretics drug
18287 Co-Betaloc SA tablets (Pfizer Ltd) CPRD_product_code res50: diuretics drug
18332 Aridil 20mg+2.5mg Tablet (C P Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
18361 Amilmaxco 5mg/50mg tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
18497 Amiloride 10mg / furosemide 80mg tablets CPRD_product_code res50: diuretics drug
18606 Diltiazem and hydrochlorothiazide 150mg+12.5mg modified-release capsules CPRD_product_code res50: diuretics drug
18650 Edecrin 50mg Tablet (Merck Sharp & Dohme Ltd) CPRD_product_code res50: diuretics drug
18716 Dryptal 10mg/ml Injection (Berk Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
18726 Triamaxco 50mg/25mg tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
18733 Co-amilozide 5mg with 50mg/ml oral solution CPRD_product_code res50: diuretics drug
18743 Tenben 25mg/1.25mg capsules (Galen Ltd) CPRD_product_code res50: diuretics drug
18903 Olmesartan medoxomil 20mg / Hydrochlorothiazide 25mg tablets CPRD_product_code res50: diuretics drug
18973 Centyl 2.5mg Tablet (Edwin Burgess Ltd) CPRD_product_code res50: diuretics drug
18983 Brinaldix k Effervescent tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
19055 Chlortalidone 12.5mg with Atenolol 50mg tablets CPRD_product_code res50: diuretics drug
19056 Furosemide 50mg/5ml sugar free Oral solution (Rosemont Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
19142 Bendroflumethiazide 2.5mg with Timolol maleate 10mg tablets CPRD_product_code res50: diuretics drug
19192 Furosemide 40mg Tablet (M & A Pharmachem Ltd) CPRD_product_code res50: diuretics drug
19194 Furosemide 20mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
19195 Spironolactone 50mg Tablet (Wyeth Pharmaceuticals) CPRD_product_code res50: diuretics drug
19258 Furosemide 50mg/5ml solution for injection ampoules CPRD_product_code res50: diuretics drug
193 Co-amilofruse 2.5mg/20mg tablets CPRD_product_code res50: diuretics drug
19300 Bumetanide 2mg/4ml solution for injection ampoules CPRD_product_code res50: diuretics drug
19352 Xuret 0.5mg Tablet (Galen Ltd) CPRD_product_code res50: diuretics drug
19890 Hydrochlorothiazide with amiloride 25mgwith2.5mg Tablet CPRD_product_code res50: diuretics drug
2 Bendroflumethiazide 2.5mg tablets CPRD_product_code res50: diuretics drug
2001 Aldactide 25 tablets (Pfizer Ltd) CPRD_product_code res50: diuretics drug
2002 Amiloride 5mg / hydrochlorothiazide 50mg tablets CPRD_product_code res50: diuretics drug
20057 Methyclothiazide 5mg Tablet CPRD_product_code res50: diuretics drug
20066 Amil-Co 5mg/50mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
20093 Metoprolol 200mg modified-release / Hydrochlorothiazide 25mg tablets CPRD_product_code res50: diuretics drug
20426 Centyl k 2.5mg+7.7mmol Tablet (Edwin Burgess Ltd) CPRD_product_code res50: diuretics drug
20431 Centyl K modified-release tablets (LEO Pharma) CPRD_product_code res50: diuretics drug
2046 Navidrex 500microgram tablets (AMCo) CPRD_product_code res50: diuretics drug
20538 Frumax 40mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
20652 Mannitol 10% Infusion CPRD_product_code res50: diuretics drug
21025 Prestim forte Tablet (LEO Pharma) CPRD_product_code res50: diuretics drug
211 Frumil 40mg+5mg Tablet (Helios Healthcare Ltd) CPRD_product_code res50: diuretics drug
21182 Hydrochlorothiazide with timolol and amiloride 25mg with 10mg with 2.5mg Tablet CPRD_product_code res50: diuretics drug
21231 Caralpha 20mg/12.5mg tablets (Actavis UK Ltd) CPRD_product_code res50: diuretics drug
2142 Spironolactone 100mg tablets CPRD_product_code res50: diuretics drug
21423 Cozaar-Comp 100mg/25mg tablets (Merck Sharp & Dohme Ltd) CPRD_product_code res50: diuretics drug
2179 Triamterene 50mg capsules CPRD_product_code res50: diuretics drug
21803 Berkozide 2.5mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
21849 Dryptal 40mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
21867 Berkozide 5mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
21873 Atenix Co 50 tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
21911 Spirospare 25mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
21938 Froop Co 5mg/40mg tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
2255 Navispare 2.5mg/250microgram tablets (AMCo) CPRD_product_code res50: diuretics drug
22658 Torem 10mg tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
22839 Clopamide with Potassium effervescent tablets CPRD_product_code res50: diuretics drug
22912 Bendroflumethiazide 2.5mg with Propanolol 80mg capsules CPRD_product_code res50: diuretics drug
22923 Hydrochlorothiazide with amiloride 50mg with 5mg Tablet CPRD_product_code res50: diuretics drug
23091 Spirospare 100 tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
23131 Bendroflumethiazide 5mg with Propanolol 160mg modified-release capsules CPRD_product_code res50: diuretics drug
23134 Nadolol 40mg / Bendroflumethiazide 5mg tablets CPRD_product_code res50: diuretics drug
23427 Bendroflumethiazide 5mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
23456 Hydrochlorothiazide with valsartan 25mg with 160mg Tablet CPRD_product_code res50: diuretics drug
23505 Adizem xl plus 150mg+12.5mg Modified-release capsule (Napp Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
2389 Aldactone 25mg tablets (Pfizer Ltd) CPRD_product_code res50: diuretics drug
24008 Vasetic Tablet (Shire Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
24189 Neo-bendromax 2.5mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
24190 Neo-bendromax 5mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
24268 Hydrochlorothiazide with valsartan 12.5mg with 80mg Tablet CPRD_product_code res50: diuretics drug
24280 Totaretic 100mg+25mg Tablet (C P Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
24484 Hydrochlorothiazide with valsartan 12.5mg with 160mg Tablet CPRD_product_code res50: diuretics drug
24632 Hydrochlorothiazide with losartan 25mg with 100mg Tablet CPRD_product_code res50: diuretics drug
24832 Lasipressin Tablet (Hoechst UK Ltd) CPRD_product_code res50: diuretics drug
24835 Min-i-jet furosemide 10mg/ml Injection (Celltech Pharma Europe Ltd) CPRD_product_code res50: diuretics drug
24893 Amilospare Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
2493 Burinex A 5mg/1mg tablets (LEO Pharma) CPRD_product_code res50: diuretics drug
2495 Bumetanide with Amiloride tablets CPRD_product_code res50: diuretics drug
25334 Furosemide 500mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
25363 Prestim tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
25382 Co-Diovan 160mg/25mg tablets (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
25494 Diatensec 50mg Tablet (Pharmacia Ltd) CPRD_product_code res50: diuretics drug
25500 Hypertane 50 Tablet (Schwarz Pharma Ltd) CPRD_product_code res50: diuretics drug
25505 Spiro-co 50mg+50mg Tablet (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
25717 Furosemide 40mg tablets (Generics (UK) Ltd) CPRD_product_code res50: diuretics drug
25730 Timolol maleate with amiloride and hydrochlorothiazide Tablet CPRD_product_code res50: diuretics drug
25965 Co-amilofruse 2.5mg/20mg tablets (Wockhardt UK Ltd) CPRD_product_code res50: diuretics drug
2612 Indapamide 2.5mg tablets CPRD_product_code res50: diuretics drug
26217 Berkamil 5mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
26219 Zida-co 5mg+50mg Tablet (Opus Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
26220 Delvas Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
26248 Tenchlor 100mg/25mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
26256 Opumide 2.5mg Tablet (Opus Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
26275 Nindaxa 2.5 tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
26292 Diuresal 40mg Tablet (Lagap) CPRD_product_code res50: diuretics drug
26529 Furosemide with penbutolol Tablet CPRD_product_code res50: diuretics drug
26741 Totaretic 50mg+12.5mg Tablet (C P Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
27256 Bendroflumethiazide 2.5mg tablets (Wockhardt UK Ltd) CPRD_product_code res50: diuretics drug
27447 Furosemide 40mg tablets (Wockhardt UK Ltd) CPRD_product_code res50: diuretics drug
27520 Olmetec Plus 20mg/25mg tablets (Daiichi Sankyo UK Ltd) CPRD_product_code res50: diuretics drug
27689 Bendroflumethiazide 2.5mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
27690 Furosemide 40mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
27696 Furosemide 40mg tablets (Kent Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
2772 Lasoride 5mg/40mg tablets (Sanofi) CPRD_product_code res50: diuretics drug
2788 Burinex 1mg tablets (LEO Pharma) CPRD_product_code res50: diuretics drug
27926 Furosemide 20mg tablets (Generics (UK) Ltd) CPRD_product_code res50: diuretics drug
27946 Nadolol 80mg / Bendroflumethiazide 5mg tablets CPRD_product_code res50: diuretics drug
27957 Natramid 2.5mg Tablet (Trinity Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
28129 Co-amilofruse 5mg/40mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
28157 Kalspare ls Tablet (Dominion Pharma) CPRD_product_code res50: diuretics drug
28177 Hydrochlorothiazide with atenolol and amiloride Capsule CPRD_product_code res50: diuretics drug
2833 CYCLOPENTHIAZIDE -K tablets CPRD_product_code res50: diuretics drug
29397 Spiretic 100mg Tablet (DDSA Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
29427 Hydrochlorothiazide with metoprolol tartrate 12.5mg with 100mg tablet CPRD_product_code res50: diuretics drug
29529 Hydroflumethiazide with spironolactone 25mg+25mg Tablet CPRD_product_code res50: diuretics drug
2961 Frusene 50mg/40mg tablets (Orion Pharma (UK) Ltd) CPRD_product_code res50: diuretics drug
29634 Olmetec Plus 20mg/12.5mg tablets (Daiichi Sankyo UK Ltd) CPRD_product_code res50: diuretics drug
29694 Inspra 50mg tablets (Pfizer Ltd) CPRD_product_code res50: diuretics drug
29696 Methoserpidine with benzthiazide Tablet CPRD_product_code res50: diuretics drug
29780 Furosemide 20mg Tablet (C P Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
2979 Centyl k Tablet (Edwin Burgess Ltd) CPRD_product_code res50: diuretics drug
2982 Zestoretic 20- 20mg+12.5mg Tablet (AstraZeneca UK Ltd) CPRD_product_code res50: diuretics drug
29991 Centyl 5mg Tablet (Edwin Burgess Ltd) CPRD_product_code res50: diuretics drug
30272 Benthiazide with Triamterene capsules CPRD_product_code res50: diuretics drug
3050 Furosemide with triamterene 40mgwith50mg Tablet CPRD_product_code res50: diuretics drug
30519 Amiloride with timolol with hydrochlorothiazide tablets CPRD_product_code res50: diuretics drug
3054 Hygroton 100mg Tablet (Alliance Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
3056 Natrilix SR 1.5mg tablets (Servier Laboratories Ltd) CPRD_product_code res50: diuretics drug
30625 Furosemide 20mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
30773 Co-amilofruse 5mg+40mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
30875 Furosemide 250mg/25ml solution for injection ampoules CPRD_product_code res50: diuretics drug
30913 Betinex 1mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
30965 Mannitol 20% Infusion CPRD_product_code res50: diuretics drug
31013 Mersalyl 50mg/ml Injection CPRD_product_code res50: diuretics drug
31131 Spiro-co 25mg+25mg Tablet (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
31150 Co-amilozide 5mg/50mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
31219 Spironolactone 100mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
31375 Amilamont 5mg/5ml oral solution sugar free (Rosemont Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
31470 Tenchlor 50mg/12.5mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
31529 Spironolactone 25mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
31548 Furosemide 20mg tablets (Actavis UK Ltd) CPRD_product_code res50: diuretics drug
31670 Bendroflumethiazide 2.5mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
31708 Co-tenidone 50mg/12.5mg tablets (Actavis UK Ltd) CPRD_product_code res50: diuretics drug
31773 Co-amilofruse 5mg/40mg tablets (Wockhardt UK Ltd) CPRD_product_code res50: diuretics drug
31820 Bendroflumethiazide 5mg tablets (Wockhardt UK Ltd) CPRD_product_code res50: diuretics drug
31932 Bumetanide 1mg tablets (C P Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
32002 Etacrynic 50mg/vial injection CPRD_product_code res50: diuretics drug
3203 Capozide LS Tablet (E R Squibb and Sons Ltd) CPRD_product_code res50: diuretics drug
32091 Bumetanide 1mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
32094 Co-tenidone 50mg/12.5mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
32166 Capto-co 25mg+50mg Tablet (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
32277 Furosemide 80mg/8ml solution for injection pre-filled syringes CPRD_product_code res50: diuretics drug
3248 Furosemide 500mg tablets CPRD_product_code res50: diuretics drug
32837 Spironolactone 50mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
3287 Furosemide 1mg/ml Oral solution CPRD_product_code res50: diuretics drug
32896 Furosemide 40mg tablets (Ranbaxy (UK) Ltd) CPRD_product_code res50: diuretics drug
32918 Furosemide 20mg tablets (Sandoz Ltd) CPRD_product_code res50: diuretics drug
3293 Moduretic Oral solution (Bristol-Myers Squibb Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
33083 Indapamide 2.5mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
33353 Lisinopril 20mg / Hydrochlorothiazide 12.5mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
33415 Bendroflumethiazide 2.5mg tablets (Generics (UK) Ltd) CPRD_product_code res50: diuretics drug
33527 Co-amilofruse 5mg/40mg tablets (Generics (UK) Ltd) CPRD_product_code res50: diuretics drug
33651 Bendroflumethiazide 2.5mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
33658 Co-amilofruse 5mg/40mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
33659 Hydrochlorothiazide with metoprolol tartrate 25mg with 200mg Modified-release tab CPRD_product_code res50: diuretics drug
33724 Diuril 250mg/5ml oral suspension (Imported (United States)) CPRD_product_code res50: diuretics drug
33837 Amiloride 5mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
34006 Furosemide 40mg tablets (Actavis UK Ltd) CPRD_product_code res50: diuretics drug
34012 Co-tenidone 100mg/25mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
34034 Co-tenidone 50mg/12.5mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
34059 Bendroflumethiazide 2.5mg tablets (Actavis UK Ltd) CPRD_product_code res50: diuretics drug
34124 Bendroflumethiazide 5mg tablets (Actavis UK Ltd) CPRD_product_code res50: diuretics drug
34280 Co-amilofruse 2.5mg/20mg tablets (Sandoz Ltd) CPRD_product_code res50: diuretics drug
34296 Spironolactone 25mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
34324 Amiloride 5mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
34347 Spironolactone 25mg tablets (Actavis UK Ltd) CPRD_product_code res50: diuretics drug
34367 Co-amilozide 2.5mg/25mg tablets (Wockhardt UK Ltd) CPRD_product_code res50: diuretics drug
34374 Furosemide 40mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
34449 Co-tenidone 50mg/12.5mg tablets (Generics (UK) Ltd) CPRD_product_code res50: diuretics drug
34551 Indapamide 2.5mg tablets (Generics (UK) Ltd) CPRD_product_code res50: diuretics drug
34557 Furosemide 40mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
34602 Bendroflumethiazide 2.5mg tablets (Sovereign Medical Ltd) CPRD_product_code res50: diuretics drug
34613 Bumetanide 5mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
34622 Co-amilofruse 10mg/80mg tablets (Wockhardt UK Ltd) CPRD_product_code res50: diuretics drug
34750 Amiloride 5mg tablets (Actavis UK Ltd) CPRD_product_code res50: diuretics drug
348 Moduretic Tablet (Bristol-Myers Squibb Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
34803 Bendroflumethiazide 2.5mg Tablet (Regent Laboratories Ltd) CPRD_product_code res50: diuretics drug
34825 Co-tenidone 50mg/12.5mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
34899 Co-tenidone 100mg/25mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
34908 Spironolactone 25mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
34934 Bumetanide 1mg tablets (Generics (UK) Ltd) CPRD_product_code res50: diuretics drug
35162 Furosemide 20mg/2ml solution for injection ampoules CPRD_product_code res50: diuretics drug
3517 Hydrochlorothiazide 50mg tablets CPRD_product_code res50: diuretics drug
35196 CoAprovel 300mg/25mg tablets (Sanofi) CPRD_product_code res50: diuretics drug
3526 Amiloride with atenolol with hydrochlorothiazide capsules CPRD_product_code res50: diuretics drug
35380 Hydrochlorothiazide with olmesartan medoxomil 12.5mg with 20mg tablet CPRD_product_code res50: diuretics drug
3548 Chlortalidone 100mg tablets CPRD_product_code res50: diuretics drug
35481 Irbesartan 300mg / Hydrochlorothiazide 25mg tablets CPRD_product_code res50: diuretics drug
35789 Spironolactone 25mg Tablet (Celltech Pharma Europe Ltd) CPRD_product_code res50: diuretics drug
36190 Furosemide 5mg/5ml oral solution sugar free CPRD_product_code res50: diuretics drug
36519 Esidrex -k Tablet (Novartis Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
36767 Bumetanide 1mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
3701 Amiloride 2.5mg / hydrochlorothiazide 25mg tablets CPRD_product_code res50: diuretics drug
37294 Triamterene with chlortalidone 50mg + 25mg Tablet CPRD_product_code res50: diuretics drug
37650 Losartan 100mg / Hydrochlorothiazide 12.5mg tablets CPRD_product_code res50: diuretics drug
37710 Lisinopril 10mg / Hydrochlorothiazide 12.5mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
37725 Co-tenidone 100mg/25mg tablets (Generics (UK) Ltd) CPRD_product_code res50: diuretics drug
37747 Cozaar-Comp 100mg/12.5mg tablets (Merck Sharp & Dohme Ltd) CPRD_product_code res50: diuretics drug
37908 Coversyl Arginine Plus 5mg/1.25mg tablets (Servier Laboratories Ltd) CPRD_product_code res50: diuretics drug
3793 Co-amilofruse 10mg/80mg tablets CPRD_product_code res50: diuretics drug
37978 Perindopril arginine 5mg / Indapamide 1.25mg tablets CPRD_product_code res50: diuretics drug
38367 Hydrochlorothiazide with losartan 12.5mg with 100mg Tablet CPRD_product_code res50: diuretics drug
38459 Telmisartan 80mg / Hydrochlorothiazide 25mg tablets CPRD_product_code res50: diuretics drug
38889 MicardisPlus 80mg/25mg tablets (Boehringer Ingelheim Ltd) CPRD_product_code res50: diuretics drug
38901 Frumil LS 20mg/2.5mg tablets (Sanofi) CPRD_product_code res50: diuretics drug
38995 Zestoretic 20 tablets (AstraZeneca UK Ltd) CPRD_product_code res50: diuretics drug
39021 Hydrochlorothiazide with olmesartan medoxomil 25mg with 20mg tablet CPRD_product_code res50: diuretics drug
39137 Zestoretic 10 tablets (AstraZeneca UK Ltd) CPRD_product_code res50: diuretics drug
39147 Carace 20 Plus tablets (Merck Sharp & Dohme Ltd) CPRD_product_code res50: diuretics drug
39227 Capozide LS 12.5mg/25mg tablets (Bristol-Myers Squibb Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
39242 Carace 10 Plus tablets (Merck Sharp & Dohme Ltd) CPRD_product_code res50: diuretics drug
39447 Varbim XL 1.5mg tablets (Teva UK Ltd) CPRD_product_code res50: diuretics drug
39602 Bumetanide 1mg tablets (Actavis UK Ltd) CPRD_product_code res50: diuretics drug
39807 Frumil 40mg/5mg tablets (Sanofi) CPRD_product_code res50: diuretics drug
3997 Hygroton 50mg tablets (Alliance Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
40149 Bendroflumethiazide 5mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res50: diuretics drug
40190 Torasemide iv 20mg/4ml Intravenous injection CPRD_product_code res50: diuretics drug
40247 Furosemide 10mg/ml Injection (Martindale Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
4034 Amiloride 5mg / hydrochlorothiazide 50mg/5ml solution CPRD_product_code res50: diuretics drug
4044 Diurexan 20mg tablets (Meda Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
4068 Dytac 50mg capsules (AMCo) CPRD_product_code res50: diuretics drug
40738 Torem iv 10mg/2ml Intravenous injection (Boehringer Mannheim UK Ltd) CPRD_product_code res50: diuretics drug
40886 Bendroflumethiazide 2.5mg tablets (Almus Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
40898 Torasemide 5mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
40907 Indapamide 2.5mg tablets (Genus Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
41074 Spironolactone 25mg tablets (Almus Pharmaceuticals Ltd) CPRD_product_code res50: diuretics drug
41292 Furosemide 20mg tablets (Wockhardt UK Ltd)