Phenotype Library | phenotype: Hba1C

Hba1C

Matthew J Carr, Alison K Wright, Lalantha Leelarantha, Hood Thabit, Nicola Milne, Naresh Kanumilli, Darren M Ashcroft, Martin K Rutter

PH833

Version ID

1745

Type

Disease or Syndrome

Data Sources

CPRD Aurum , CPRD GOLD

Valid event data range

01/01/2010 - 29/02/2020

Sex

♀ Female ♂ Male

Agreement Date

2021-05-11

Coding system

Read codes v2 SNOMED CT codes

Collections

ClinicalCodes Repository Phenotype Library

Definition

We generated a cohort of 25 million patients from 1831 UK general practices registered with the Clinical Practice Research Datalink (CPRD) Aurum (inEngland) and CPRD GOLD (in Northern Ireland, Scotland, and Wales) databases. The cohort included 14 929 251 patients (median age 41 years [IQR 25–59]; 7 461 565 [50·0%] of whom were women), who were followed between March 1 and Dec 10, 2020. We aimed to compare: (1) the UK-wide incidence of type 2 diabetes; (2) the frequency of HbA1c testing; and (3) mortality in people with type 2 diabetes, by nation, before and after the first nationwide COVID-19 lockdown, which began in March 23, 2020 (appendix pp 1–3). There were 790 377 (5·3%) people with type 2 diabetes in the cohort (median age 67 years (IQR 57–76); 348 515 (44·1%) of whom were women).

Publications

Matthew J Carr, Alison K Wright, Lalantha Leelarantha, Hood Thabit, Nicola Milne, Naresh Kanumilli, Darren M Ashcroft, Martin K Rutter, Impact of COVID-19 on diagnoses, monitoring, and mortality in people with type 2 diabetes in the UK. The Lancet Diabetes Endocrinology, 9, 2021.

Clinical Code List

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C2589/6591 Hba1C - Primary Care - Read codes v2

Rows: 36

Code	Description	Entity type	Coding System (Read SNOMED)	Category
423..00	Haemoglobin estimation	res166: HbA1c	Read	test
423..11	Hb estimation	res166: HbA1c	Read	test
42V2.00	Haemoglobin A	res166: HbA1c	Read	test
42V2000	Haemoglobin A quantitation	res166: HbA1c	Read	test
42VA.00	Haemoglobin variant test	res166: HbA1c	Read	test
42W..00	Hb. A1C - diabetic control	res166: HbA1c	Read	test
42W..11	Glycosylated Hb	res166: HbA1c	Read	test
42W..12	Glycated haemoglobin	res166: HbA1c	Read	test
42W1.00	Hb. A1C < 7% - good control	res166: HbA1c	Read	test
42W2.00	Hb. A1C 7-10% - borderline	res166: HbA1c	Read	test
42W3.00	Hb. A1C > 10% - bad control	res166: HbA1c	Read	test
42W4.00	HbA1c level (DCCT aligned)	res166: HbA1c	Read	test
42W5.00	Haemoglobin A1c level - IFCC standardised	res166: HbA1c	Read	test
42WZ.00	Hb. A1C - diabetic control NOS	res166: HbA1c	Read	test
42c..00	HbA1 - diabetic control	res166: HbA1c	Read	test
42c0.00	HbA1 < 7% - good control	res166: HbA1c	Read	test
42c1.00	HbA1 7 - 10% - borderline control	res166: HbA1c	Read	test
42c2.00	HbA1 > 10% - bad control	res166: HbA1c	Read	test
42c3.00	HbA1 level (DCCT aligned)	res166: HbA1c	Read	test
44T1200	Random blood sugar raised	res166: HbA1c	Read	test
44T2.00	Fasting blood sugar	res166: HbA1c	Read	test
44TB.00	Haemoglobin A1c level	res166: HbA1c	Read	test
44TB000	Haemoglobin A1c (diagnostic reference range)	res166: HbA1c	Read	test
44TB100	Haemoglobin A1c (monitoring ranges)	res166: HbA1c	Read	test
44TC.00	Haemoglobin A1 level	res166: HbA1c	Read	test
44TJ.00	Blood glucose level	res166: HbA1c	Read	test
44TK.00	Fasting blood glucose level	res166: HbA1c	Read	test
44TL.00	Total glycosylated haemoglobin level	res166: HbA1c	Read	test
44U..00	Blood glucose result	res166: HbA1c	Read	test
44U..11	Blood sugar result	res166: HbA1c	Read	test
44U5.00	Blood glucose 7-9.9 mmol/L	res166: HbA1c	Read	test
44U6.00	Blood glucose 10-13.9 mmol/L	res166: HbA1c	Read	test
66Ae.00	HBA1c target	res166: HbA1c	Read	test
66Ae000	HbA1c target level - IFCC standardised	res166: HbA1c	Read	test
C109711	Type II diabetes mellitus - poor control	res166: HbA1c	Read	test
C10F711	Type II diabetes mellitus - poor control	res166: HbA1c	Read	test

C2590/6593 Hba1C - Primary Care - SNOMED CT codes

Rows: 30

Code	Description	Entity type	Coding System (Read SNOMED)	Category
1.09871E+14	Test request : Haemoglobin A1c	res166: HbA1c	SNOMED	test
1.29761E+14	Haemoglobin A1c level	res166: HbA1c	SNOMED	test
1.72528E+15	HbA1c (haemoglobin A1c) target - IFCC (International Federation of Clinical Chemistry and Laboratory	res166: HbA1c	SNOMED	test
1.72875E+15	Haemoglobin A1c target - International Federation of Clinical Chemistry and Laboratory Medicine stan	res166: HbA1c	SNOMED	test
1.92779E+15	Raised HbA1c level	res166: HbA1c	SNOMED	test
2.64314E+15	HbA1c level (monitoring ranges) - IFCC standardised	res166: HbA1c	SNOMED	test
2.6431E+15	HbA1c level (diagnostic reference range) - IFCC standardised	res166: HbA1c	SNOMED	test
2160141012	HBA1c target	res166: HbA1c	SNOMED	test
2163995019	Target HbA1c level	res166: HbA1c	SNOMED	test
2621920018	Haemoglobin A1c (HBA1c) target	res166: HbA1c	SNOMED	test
2621921019	Hemoglobin A1c (HBA1c) target	res166: HbA1c	SNOMED	test
2767753013	Haemoglobin A1c (HbA1c) greater than 10% indicating poor diabetic control	res166: HbA1c	SNOMED	test
2767755018	Hemoglobin A1c greater than 10% indicating poor diabetic control	res166: HbA1c	SNOMED	test
2768431010	Hemoglobin A1c between 7%-10% indicating borderline diabetic control	res166: HbA1c	SNOMED	test
2769803019	Hemoglobin A1c less than 7% indicating good diabetic control	res166: HbA1c	SNOMED	test
2770714019	Hemoglobin A1c (HbA1c) between 7%-10% indicating borderline diabetic control	res166: HbA1c	SNOMED	test
2772122013	Hemoglobin A1c (HbA1c) less than 7% indicating good diabetic control	res166: HbA1c	SNOMED	test
2772787010	Haemoglobin A1c (HbA1c) between 7%-10% indicating borderline diabetic control	res166: HbA1c	SNOMED	test
2773408014	Hemoglobin A1c (HbA1c) greater than 10% indicating poor diabetic control	res166: HbA1c	SNOMED	test
2773783018	Haemoglobin A1c (HbA1c) less than 7% indicating good diabetic control	res166: HbA1c	SNOMED	test
2883676014	Hemoglobin A1c target value using International Federation of Clinical Chemistry and Laboratory Medi	res166: HbA1c	SNOMED	test
2883677017	Haemoglobin A1c target value using International Federation of Clinical Chemistry and Laboratory Med	res166: HbA1c	SNOMED	test
2914480010	Hemoglobin A1c target	res166: HbA1c	SNOMED	test
4.59526E+15	Haemoglobin A1c less than 7% indicating good diabetic control	res166: HbA1c	SNOMED	test
404443010	Hemoglobin A1C - diabetic control interpretation	res166: HbA1c	SNOMED	test
489331011	Hemoglobin A1C - diabetic control finding	res166: HbA1c	SNOMED	test
493589010	HbA1c - Haemoglobin A1c level	res166: HbA1c	SNOMED	test
493590018	HbA1c - Hemoglobin A1c level	res166: HbA1c	SNOMED	test
72394011	Hemoglobin A1c measurement	res166: HbA1c	SNOMED	test
72395012	Haemoglobin A1c measurement	res166: HbA1c	SNOMED	test

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH833/version/1745/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH833/version/1745/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH833', '1745', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH833/version/1745/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH833/version/1745/export/codes/?format=json
CSV	site_root/phenotypes/PH833/version/1745/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH833', '1745', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
1745	Hba1C	ieuan.scanlon	2022-04-04	currently shown