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Sinusitis

Victoria Palin, Anna Molter, Miguel Belmonte, Darren M Ashcroft, Andrew White, William Welfare, Tjeerd van Staa

Type
Disease or Syndrome
ID
PH903
Version ID
1885
Data Sources
Valid event data range
01/01/2000 - 30/06/2015
Sex
Female, Male
Agreement Date
2019-04-30
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Objectives:

To examine variations across general practices and factors associated with antibiotic prescribing for common infections in UK primary care to identify potential targets for improvement and optimization of prescribing.

Methods:

Oral antibiotic prescribing for common infections was analysed using anonymized UK primary care electronic health records between 2000 and 2015 using the Clinical Practice Research Datalink (CPRD). The rate of prescribing for each condition was observed over time and mean change points were compared with national guideline updates. Any correlation between the rate of prescribing for each infectious condition was estimated within a practice. Predictors of prescribing were estimated using logistic regression in a matched patient cohort (1:1 by age, sex and calendar time).

Results:

Over 8 million patient records were examined in 587 UK general practices. Practices varied considerably in their propensity to prescribe antibiotics and this variance increased over time. Change points in prescribing did not reflect updates to national guidelines. Prescribing levels within practices were not consistent for different infectious conditions. A history of antibiotic use significantly increased the risk of receiving a subsequent antibiotic (by 22%–48% for patients with three or more antibiotic prescriptions in the past 12months), as did higher BMI, history of smoking and flu vaccinations. Other drivers for receiving an antibiotic varied considerably for each condition.

Conclusions:

Large variability in antibiotic prescribing between practices and within practices was observed. Prescribing guidelines alone do not positively influence a change in prescribing, suggesting more targeted interventions are required to optimize antibiotic prescribing in the UK.

Publications

  • Victoria Palin, Anna Molter, Darren M Ashcroft, Andrew White, William Welfare, Tjeerd van Staa, Antibiotic prescribing for common infections in UK general practice variability and drivers. Journal of Antimicrobial Chemotherapy, 74:2440-2450, 2019.

Clinical Code List

Rows: 25
Code Description Entity type Category Coding System (Read)
H01..00 Acute sinusitis res70: Sinusitis diagnostic Read
H01..11 Sinusitis res70: Sinusitis diagnostic Read
H010.00 Acute maxillary sinusitis res70: Sinusitis diagnostic Read
H011.00 Acute frontal sinusitis res70: Sinusitis diagnostic Read
H012.00 Acute ethmoidal sinusitis res70: Sinusitis diagnostic Read
H013.00 Acute sphenoidal sinusitis res70: Sinusitis diagnostic Read
H014.00 Acute rhinosinusitis res70: Sinusitis diagnostic Read
H01y.00 Other acute sinusitis res70: Sinusitis diagnostic Read
H01yz00 Other acute sinusitis NOS res70: Sinusitis diagnostic Read
H01z.00 Acute sinusitis NOS res70: Sinusitis diagnostic Read
H13..00 Chronic sinusitis res70: Sinusitis diagnostic Read
H13..11 Chronic rhinosinusitis res70: Sinusitis diagnostic Read
H130.00 Chronic maxillary sinusitis res70: Sinusitis diagnostic Read
H130.11 Antritis - chronic res70: Sinusitis diagnostic Read
H130.12 Maxillary sinusitis res70: Sinusitis diagnostic Read
H131.00 Chronic frontal sinusitis res70: Sinusitis diagnostic Read
H131.11 Frontal sinusitis res70: Sinusitis diagnostic Read
H132.00 Chronic ethmoidal sinusitis res70: Sinusitis diagnostic Read
H134.00 Fistula of nasal sinus res70: Sinusitis diagnostic Read
H135.00 Recurrent sinusitis res70: Sinusitis diagnostic Read
H13y.00 Other chronic sinusitis res70: Sinusitis diagnostic Read
H13y000 Chronic pansinusitis res70: Sinusitis diagnostic Read
H13y100 Pansinusitis res70: Sinusitis diagnostic Read
H13yz00 Other chronic sinusitis NOS res70: Sinusitis diagnostic Read
H13z.00 Chronic sinusitis NOS res70: Sinusitis diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH903/version/1885/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH903/version/1885/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH903', '1885', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH903/version/1885/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH903/version/1885/export/codes/?format=json
CSV site_root/phenotypes/PH903/version/1885/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH903', '1885', api_client=client)

Version History

Version
ID
Name Owner Publish date
1885 Sinusitis ieuan.scanlon 2022-04-04 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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