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Alcohol Consumption

Rosa Parisi, Roger T. Webb, Mathew J. Carr, Kieran J. Moriarty, Elise Kleyn, Christopher E. M. Griffiths, Darren M. Ashcroft

Type
Lifestyle Risk Factor
ID
PH909
Version ID
1897
Data Sources
Valid event data range
01/01/1998 - 03/03/2014
Sex
Female, Male
Agreement Date
2017-09-15
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

IMPORTANCE:

People diagnosed with psoriasis have an increased risk of premature mortality, but the underlying reasons for this mortality gap are unclear.

OBJECTIVE:

To investigate whether patients with psoriasis have an elevated risk of alcohol-related mortality.

DESIGN, SETTING, AND PARTICIPANTS:

An incident cohort of patients with psoriasis aged 18 years and older was delineated for 1998 through 2014 using the Clinical Practice Research atalink (CPRD) and linked to Hospital Episode Statistics (HES) and Office for National tatistics (ONS) mortality records. Patients with psoriasis were matched with up to 20 comparison patients without psoriasis on age, sex, and general practice.

MAIN OUTCOMES AND MEASURES:

Alcohol-related deathswere ascertained via the Office for National Statistics mortality records. A stratified Cox proportional hazard model was used to estimate the cause-specific hazard ratio for alcohol-related death, with adjustment for socioeconomic status.

RESULTS:

The cohort included 55 537 with psoriasis and 854 314 patients without psoriasis. Median (interquartile) age at index date was 47 (27) years; 408 230 of total patients (44.9%) were men. During a median (IQR) of 4.4 (6.2) years of follow-up, the alcohol-related mortality rate was 4.8 per 10 000 person-years (95%CI, 4.1-5.6; n = 152) for the psoriasis cohort, vs 2.5 per 10 000 (95%CI, 2.4- 2.7; n = 1118) for the comparison cohort. The hazard ratio for alcohol-related death in patients with psoriasis was 1.58 (95%CI, 1.31-1.91), and the predominant causes of alcohol-related deaths were alcoholic liver disease (65.1%), fibrosis and cirrhosis of the liver (23.7%), and mental and behavioral disorders due to alcohol (7.9%).

CONCLUSIONS AND RELEVANCE:

People with psoriasis have approximately a 60%greater risk of dying due to alcohol-related causes compared with peers of the same age and sex in the general population. This appears to be a key contributor to the premature mortality gap. These findings call for routine screening, identification and treatment, using the Alcohol Use Disorders Identification Test (AUDIT-C) in both primary and secondary care to detect alcohol consumption and misuse among people diagnosed with psoriasis.

Publications

  • Rosa Parisi, Roger T. Webb, Mathew J. Carr, Kieran J. Moriarty, Elise Kleyn, Christopher E. M. Griffiths, Darren M. Ashcroft, Alcohol-Related Mortality in Patients With Psoriasis A Population-Based Cohort Study. JAMA Dermatology, 153(12):1256-1262, 2017.

Clinical Code List

Rows: 191
Code Description Entity type Category Coding System (Read)
136..00 Alcohol consumption res61: alcohol consumption diagnostic Read
1361 Teetotaller res61: alcohol consumption diagnostic Read
1361.11 Non drinker alcohol res61: alcohol consumption diagnostic Read
1361.12 Non-drinker alcohol res61: alcohol consumption diagnostic Read
1362 Trivial drinker - <1u/day res61: alcohol consumption diagnostic Read
1362.11 Drinks rarely res61: alcohol consumption diagnostic Read
1362.12 Drinks occasionally res61: alcohol consumption diagnostic Read
1363 Light drinker - 1-2u/day res61: alcohol consumption diagnostic Read
1364 Moderate drinker - 3-6u/day res61: alcohol consumption diagnostic Read
1365 Heavy drinker - 7-9u/day res61: alcohol consumption diagnostic Read
1366 Very heavy drinker - >9u/day res61: alcohol consumption diagnostic Read
1367 Stopped drinking alcohol res61: alcohol consumption diagnostic Read
136A.00 Ex-trivial drinker (<1u/day) res61: alcohol consumption diagnostic Read
136B.00 Ex-light drinker - (1-2u/day) res61: alcohol consumption diagnostic Read
136C.00 Ex-moderate drinker - (3-6u/d) res61: alcohol consumption diagnostic Read
136D.00 Ex-heavy drinker - (7-9u/day) res61: alcohol consumption diagnostic Read
136E.00 Ex-very heavy drinker-(>9u/d) res61: alcohol consumption diagnostic Read
136F.00 Spirit drinker res61: alcohol consumption diagnostic Read
136G.00 Beer drinker res61: alcohol consumption diagnostic Read
136H.00 Drinks beer and spirits res61: alcohol consumption diagnostic Read
136I.00 Drinks wine res61: alcohol consumption diagnostic Read
136J.00 Social drinker res61: alcohol consumption diagnostic Read
136K.00 Alcohol intake above recommended sensible limits res61: alcohol consumption diagnostic Read
136L.00 Alcohol intake within recommended sensible limits res61: alcohol consumption diagnostic Read
136M.00 Current non drinker res61: alcohol consumption diagnostic Read
136N.00 Light drinker res61: alcohol consumption diagnostic Read
136O.00 Moderate drinker res61: alcohol consumption diagnostic Read
136P.00 Heavy drinker res61: alcohol consumption diagnostic Read
136Q.00 Very heavy drinker res61: alcohol consumption diagnostic Read
136R.00 Binge drinker res61: alcohol consumption diagnostic Read
136S.00 Hazardous alcohol use res61: alcohol consumption diagnostic Read
136T.00 Harmful alcohol use res61: alcohol consumption diagnostic Read
136V.00 Alcohol units per week res61: alcohol consumption diagnostic Read
136W.00 Alcohol misuse res61: alcohol consumption diagnostic Read
136X.00 Alcohol units consumed on heaviest drinking day res61: alcohol consumption diagnostic Read
136Y.00 Drinks in morning to get rid of hangover res61: alcohol consumption diagnostic Read
136Z.00 Alcohol consumption NOS res61: alcohol consumption diagnostic Read
136a.00 Increasing risk drinking res61: alcohol consumption diagnostic Read
136b.00 Feels should cut down drinking res61: alcohol consumption diagnostic Read
136c.00 Higher risk drinking res61: alcohol consumption diagnostic Read
136d.00 Lower risk drinking res61: alcohol consumption diagnostic Read
13Y8.00 Alcoholics anonymous res61: alcohol consumption diagnostic Read
13ZY.00 Disqualified from driving due to excess alcohol res61: alcohol consumption diagnostic Read
1462 H/O: alcoholism res61: alcohol consumption diagnostic Read
1B1c.00 Alcohol induced hallucinations res61: alcohol consumption diagnostic Read
1D19.00 Pain in lymph nodes after alcohol consumption res61: alcohol consumption diagnostic Read
2577 O/E - breath - alcohol smell res61: alcohol consumption diagnostic Read
2577.11 O/E - alcoholic breath res61: alcohol consumption diagnostic Read
38Dz.00 Severity of alcohol dependence questionnaire res61: alcohol consumption diagnostic Read
38Dz.11 SADQ - Severity of alcohol dependence questionnaire res61: alcohol consumption diagnostic Read
63C7.00 Maternal alcohol abuse res61: alcohol consumption diagnostic Read
66e..00 Alcohol disorder monitoring res61: alcohol consumption diagnostic Read
66e0.00 alcohol abuse monitoring res61: alcohol consumption diagnostic Read
7P22100 Delivery of rehabilitation for alcohol addiction res61: alcohol consumption diagnostic Read
8BA8.00 alcohol detoxification res61: alcohol consumption diagnostic Read
8CAM000 Advised to abstain from alcohol consumption res61: alcohol consumption diagnostic Read
8CAv.00 advised to contact primary care alcohol worker res61: alcohol consumption diagnostic Read
8G32.00 Aversion therapy - alcoholism res61: alcohol consumption diagnostic Read
8H35.00 admitted to alcohol detoxification centre res61: alcohol consumption diagnostic Read
8H7p.00 Referral to community alcohol team res61: alcohol consumption diagnostic Read
8HHe.00 Referral to community drug and alcohol team res61: alcohol consumption diagnostic Read
8HkG.00 Referral to specialist alcohol treatment service res61: alcohol consumption diagnostic Read
8HkJ.00 Referral to alcohol brief intervention service res61: alcohol consumption diagnostic Read
8IAF.00 brief intervention for excessive alcohol consumptn declined res61: alcohol consumption diagnostic Read
8IAJ.00 declined referral to specialist alcohol treatment service res61: alcohol consumption diagnostic Read
8IAt.00 Extended intervention for excessive alcohol consumption declined res61: alcohol consumption diagnostic Read
9EQ..11 Police:venesect-alcohol res61: alcohol consumption diagnostic Read
9NN2.00 Under care of community alcohol team res61: alcohol consumption diagnostic Read
9k1..00 Alcohol misuse - enhanced services administration res61: alcohol consumption diagnostic Read
9k11.00 Alcohol consumption counselling res61: alcohol consumption diagnostic Read
9k12.00 Alcohol misuse - enhanced service completed res61: alcohol consumption diagnostic Read
9k19.00 Alcohol assesment declined - enhanced services admin res61: alcohol consumption diagnostic Read
9k1A.00 Brief intervention for excessive alcohol consumptn completed res61: alcohol consumption diagnostic Read
9k1B.00 Extended intervention for excessive alcohol consumption completed res61: alcohol consumption diagnostic Read
C150500 Alcohol-induced pseudo-Cushing's syndrome res61: alcohol consumption diagnostic Read
E01..00 Alcoholic psychoses res61: alcohol consumption diagnostic Read
E010.00 Alcohol withdrawal delirium res61: alcohol consumption diagnostic Read
E011.00 Alcohol amnestic syndrome res61: alcohol consumption diagnostic Read
E011000 Korsakov's alcoholic psychosis res61: alcohol consumption diagnostic Read
E011100 Korsakov's alcoholic psychosis with peripheral neuritis res61: alcohol consumption diagnostic Read
E011200 Wernicke-Korsakov syndrome res61: alcohol consumption diagnostic Read
E011z00 Alcohol amnestic syndrome NOS res61: alcohol consumption diagnostic Read
E012.00 Other alcoholic dementia res61: alcohol consumption diagnostic Read
E012.11 alcoholic dementia nos res61: alcohol consumption diagnostic Read
E012000 Chronic alcoholic brain syndrome res61: alcohol consumption diagnostic Read
E013.00 Alcohol withdrawal hallucinosis res61: alcohol consumption diagnostic Read
E014.00 pathological alcohol intoxication res61: alcohol consumption diagnostic Read
E015.00 Alcoholic paranoia res61: alcohol consumption diagnostic Read
E01y.00 Other alcoholic psychosis res61: alcohol consumption diagnostic Read
E01y000 Alcohol withdrawal syndrome res61: alcohol consumption diagnostic Read
E01yz00 Other alcoholic psychosis NOS res61: alcohol consumption diagnostic Read
E01z.00 Alcoholic psychosis NOS res61: alcohol consumption diagnostic Read
E23..00 Alcohol dependence syndrome res61: alcohol consumption diagnostic Read
E23..11 Alcoholism res61: alcohol consumption diagnostic Read
E23..12 Alcohol problem drinking res61: alcohol consumption diagnostic Read
E230.00 Acute alcoholic intoxication in alcoholism res61: alcohol consumption diagnostic Read
E230.11 Alcohol dependence with acute alcoholic intoxication res61: alcohol consumption diagnostic Read
E230000 Acute alcoholic intoxication, unspecified, in alcoholism res61: alcohol consumption diagnostic Read
E230100 Continuous acute alcoholic intoxication in alcoholism res61: alcohol consumption diagnostic Read
E230200 Episodic acute alcoholic intoxication in alcoholism res61: alcohol consumption diagnostic Read
E230300 Acute alcoholic intoxication in remission, in alcoholism res61: alcohol consumption diagnostic Read
E230z00 Acute alcoholic intoxication in alcoholism NOS res61: alcohol consumption diagnostic Read
E231.00 Chronic alcoholism res61: alcohol consumption diagnostic Read
E231.11 Dipsomania res61: alcohol consumption diagnostic Read
E231000 Unspecified chronic alcoholism res61: alcohol consumption diagnostic Read
E231100 Continuous chronic alcoholism res61: alcohol consumption diagnostic Read
E231200 Episodic chronic alcoholism res61: alcohol consumption diagnostic Read
E231300 Chronic alcoholism in remission res61: alcohol consumption diagnostic Read
E231z00 Chronic alcoholism NOS res61: alcohol consumption diagnostic Read
E23z.00 Alcohol dependence syndrome NOS res61: alcohol consumption diagnostic Read
E250.00 Nondependent alcohol abuse res61: alcohol consumption diagnostic Read
E250.11 Drunkenness NOS res61: alcohol consumption diagnostic Read
E250.12 Hangover (alcohol) res61: alcohol consumption diagnostic Read
E250.13 Inebriety NOS res61: alcohol consumption diagnostic Read
E250.14 Intoxication - alcohol res61: alcohol consumption diagnostic Read
E250000 Nondependent alcohol abuse, unspecified res61: alcohol consumption diagnostic Read
E250100 Nondependent alcohol abuse, continuous res61: alcohol consumption diagnostic Read
E250200 Nondependent alcohol abuse, episodic res61: alcohol consumption diagnostic Read
E250300 Nondependent alcohol abuse in remission res61: alcohol consumption diagnostic Read
E250z00 Nondependent alcohol abuse NOS res61: alcohol consumption diagnostic Read
Eu10.00 [X]Mental and behavioural disorders due to use of alcohol res61: alcohol consumption diagnostic Read
Eu10000 [X]Mental & behav dis due to use alcohol: acute intoxication res61: alcohol consumption diagnostic Read
Eu10011 [X]Acute alcoholic drunkenness res61: alcohol consumption diagnostic Read
Eu10100 [X]Mental and behav dis due to use of alcohol: harmful use res61: alcohol consumption diagnostic Read
Eu10200 [X]Mental and behav dis due to use alcohol: dependence syndr res61: alcohol consumption diagnostic Read
Eu10211 [X]Alcohol addiction res61: alcohol consumption diagnostic Read
Eu10212 [X]Chronic alcoholism res61: alcohol consumption diagnostic Read
Eu10213 [X]Dipsomania res61: alcohol consumption diagnostic Read
Eu10300 [X]Mental and behavioural disorders due to use of alcohol: withdrawal state res61: alcohol consumption diagnostic Read
Eu10400 [X]Mental and behavioural disorders due to use of alcohol: withdrawal state with delirium res61: alcohol consumption diagnostic Read
Eu10411 [x]delirium tremens, alcohol induced res61: alcohol consumption diagnostic Read
Eu10500 [X]Mental and behavioural disorders due to use of alcohol: psychotic disorder res61: alcohol consumption diagnostic Read
Eu10511 [X]Alcoholic hallucinosis res61: alcohol consumption diagnostic Read
Eu10512 [x]alcoholic jealousy res61: alcohol consumption diagnostic Read
Eu10513 [X]Alcoholic paranoia res61: alcohol consumption diagnostic Read
Eu10514 [X]Alcoholic psychosis NOS res61: alcohol consumption diagnostic Read
Eu10600 [X]Mental and behavioural disorders due to use of alcohol: amnesic syndrome res61: alcohol consumption diagnostic Read
Eu10611 [x]korsakov's psychosis, alcohol induced res61: alcohol consumption diagnostic Read
Eu10700 [X]Mental and behavioural disorders due to use of alcohol: residual and late-onset psychotic disorde res61: alcohol consumption diagnostic Read
Eu10711 [X]Alcoholic dementia NOS res61: alcohol consumption diagnostic Read
Eu10712 [X]Chronic alcoholic brain syndrome res61: alcohol consumption diagnostic Read
Eu10800 [X]Alcohol withdrawal-induced seizure res61: alcohol consumption diagnostic Read
Eu10y00 [X]Mental and behavioural disorders due to use of alcohol: other mental and behavioural disorders res61: alcohol consumption diagnostic Read
Eu10z00 [X]Mental and behavioural disorders due to use of alcohol: unspecified mental and behavioural disord res61: alcohol consumption diagnostic Read
F11x000 Cerebral degeneration due to alcoholism res61: alcohol consumption diagnostic Read
F11x011 Alcoholic encephalopathy res61: alcohol consumption diagnostic Read
F144000 Cerebellar ataxia due to alcoholism res61: alcohol consumption diagnostic Read
F25B.00 Alcohol-induced epilepsy res61: alcohol consumption diagnostic Read
F375.00 Alcoholic polyneuropathy res61: alcohol consumption diagnostic Read
F394100 Alcoholic myopathy res61: alcohol consumption diagnostic Read
G555.00 Alcoholic cardiomyopathy res61: alcohol consumption diagnostic Read
G852300 Oesophageal varices in alcoholic cirrhosis of the liver res61: alcohol consumption diagnostic Read
J153.00 Alcoholic gastritis res61: alcohol consumption diagnostic Read
J610.00 Alcoholic fatty liver res61: alcohol consumption diagnostic Read
J611.00 Acute alcoholic hepatitis res61: alcohol consumption diagnostic Read
J612.00 Alcoholic cirrhosis of liver res61: alcohol consumption diagnostic Read
J612000 Alcoholic fibrosis and sclerosis of liver res61: alcohol consumption diagnostic Read
J613.00 Alcoholic liver damage unspecified res61: alcohol consumption diagnostic Read
J613000 Alcoholic hepatic failure res61: alcohol consumption diagnostic Read
J617.00 Alcoholic hepatitis res61: alcohol consumption diagnostic Read
J617000 Chronic alcoholic hepatitis res61: alcohol consumption diagnostic Read
J671000 Alcohol-induced chronic pancreatitis res61: alcohol consumption diagnostic Read
L255300 Maternal care for (suspected) damage to fetus from alcohol res61: alcohol consumption diagnostic Read
R103.00 [D]Alcohol blood level excessive res61: alcohol consumption diagnostic Read
SM0..00 Alcohol causing toxic effect res61: alcohol consumption diagnostic Read
SM00.00 Ethyl alcohol causing toxic effect res61: alcohol consumption diagnostic Read
SM00z00 Ethyl alcohol causing toxic effect NOS res61: alcohol consumption diagnostic Read
SM0z.00 Alcohol causing toxic effect NOS res61: alcohol consumption diagnostic Read
U60H300 [X]Alcohol deterrents causing adverse effects in therapeutic use res61: alcohol consumption diagnostic Read
U60H311 [X] Adverse reaction to alcohol deterrents res61: alcohol consumption diagnostic Read
U81..00 [X]Evid of alcohol involv determind by level of intoxication res61: alcohol consumption diagnostic Read
Z191.00 alcohol detoxification res61: alcohol consumption diagnostic Read
Z191100 alcohol withdrawal regime res61: alcohol consumption diagnostic Read
Z191200 Planned reduction of alcohol consumption res61: alcohol consumption diagnostic Read
Z191211 alcohol reduction programme res61: alcohol consumption diagnostic Read
Z191400 Self-monitoring of alcohol intake res61: alcohol consumption diagnostic Read
Z4B1.00 Alcoholism counselling res61: alcohol consumption diagnostic Read
ZC22200 Advice to change alcoholic drink intake res61: alcohol consumption diagnostic Read
ZC2H.00 Advice to change alcohol intake res61: alcohol consumption diagnostic Read
ZG23100 Advice on alcohol consumption res61: alcohol consumption diagnostic Read
ZR1E.00 Alcohol dependence scale res61: alcohol consumption diagnostic Read
ZR1E.11 ads - alcohol dependence scale res61: alcohol consumption diagnostic Read
ZR1G.00 Alcohol use inventory res61: alcohol consumption diagnostic Read
ZRa1100 Brief Michigan alcoholism screening test res61: alcohol consumption diagnostic Read
ZRk6.00 Severity of alcohol dependence questionnaire res61: alcohol consumption diagnostic Read
ZRk6.11 SADQ - Severity of alcohol dependence questionnaire res61: alcohol consumption diagnostic Read
ZV11300 [V]Personal history of alcoholism res61: alcohol consumption diagnostic Read
ZV11311 [V]Problems related to lifestyle alcohol use res61: alcohol consumption diagnostic Read
ZV4KC00 [V] Alcohol use res61: alcohol consumption diagnostic Read
ZV57A00 [V]Alcohol rehabilitation res61: alcohol consumption diagnostic Read
ZV6D600 [V]Alcohol abuse counselling and surveillance res61: alcohol consumption diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH909/version/1897/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH909/version/1897/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH909', '1897', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH909/version/1897/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH909/version/1897/export/codes/?format=json
CSV site_root/phenotypes/PH909/version/1897/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH909', '1897', api_client=client)

Version History

Version
ID
Name Owner Publish date
1897 Alcohol Consumption ieuan.scanlon 2022-04-04 currently shown

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