Print

Psoriasis

Rosa Parisi, Martin K Rutter, Mark Lunt, Helen S Young, Deborah P M Symmons, Christopher E M Griffiths, Darren M. Ashcroft

ID
PH912
Version ID
1903
Type
Disease or Syndrome
Data Sources
Valid event data range
01/01/1994 - 31/12/2009
Sex
♀  Female ♂  Male
Agreement Date
2015-04-09
Coding system
Read codes v2
Collections
ClinicalCodes Repository Phenotype Library
Tags
No tags

Definition

The association between psoriasis and risk of major cardiovascular (CV) events (myocardial infarction, acute coronary syndrome, unstable angina, and stroke) is unclear. A cohort study with 48,523 patients with psoriasis and 208,187 controls was conducted. During a median follow-up of 5.2 years, 1,257 patients with psoriasis (2.59%) had a major CV event, compared with 4,784 controls (2.30%). In the multivariable analysis, inflammatory arthritis hazard ratio (HR) 1.36 (1.18–1.58), diabetes HR 1.18 (1.06–1.31), chronic kidney disease HR 1.18 (1.07–1.31), hypertension HR 1.37 (1.29–1.45), transient ischemic attack HR 2.74 (2.41–3.12), atrial fibrillation HR 1.54 (1.36–1.73), valvular heart disease HR 1.23 (1.05–1.44), thromboembolism 1.32 (1.17–1.49), congestive heart failure HR 1.57 (1.39–1.78), depression HR 1.16 (1.01–1.34), current smoker HR 2.18 (2.03–2.33), age (year) HR 1.07 (1.07–1.07), and male gender HR 1.83 (1.69–1.98) were statistically significant for the risk of major CV events. The age- and genderadjusted HRs of a major CV event for psoriasis were 1.10 (1.04–1.17) and for severe psoriasis 1.40 (1.07–1.84), whereas the fully adjusted HRs were attenuated to 1.02 (0.95–1.08) and 1.28 (0.96–1.69). In conclusion, neither psoriasis nor severe psoriasis were associated with the short-to-medium term (over 3–5 years) risk of major CV events after adjusting for known cardiovascular disease risk factors.

Publications

  • Rosa Parisi, Martin K Rutter, Mark Lunt, Helen S Young, Deborah P M Symmons, Christopher E M Griffiths, Darren M. Ashcroft, Psoriasis and the Risk of Major Cardiovascular Events Cohort Study Using the Clinical Practice Research Datalink. Journal of Investigative Dermatology, 135, 2015.

Clinical Code List

Rows: 24
Code Description Entity type Category Coding System (Read)
M16..00 Psoriasis and similar disorders res66: psoriasis diagnostic Read
M161.00 Other psoriasis res66: psoriasis diagnostic Read
M161000 Psoriasis unspecified res66: psoriasis diagnostic Read
M161100 Psoriasis annularis res66: psoriasis diagnostic Read
M161200 Psoriasis circinata res66: psoriasis diagnostic Read
M161300 Psoriasis diffusa res66: psoriasis diagnostic Read
M161400 Psoriasis discoidea res66: psoriasis diagnostic Read
M161500 Psoriasis geographica res66: psoriasis diagnostic Read
M161600 Guttate psoriasis res66: psoriasis diagnostic Read
M161700 Psoriasis gyrata res66: psoriasis diagnostic Read
M161800 Psoriasis inveterata res66: psoriasis diagnostic Read
M161900 Psoriasis ostracea res66: psoriasis diagnostic Read
M161A00 Psoriasis palmaris res66: psoriasis diagnostic Read
M161B00 Psoriasis plantaris res66: psoriasis diagnostic Read
M161C00 Psoriasis punctata res66: psoriasis diagnostic Read
M161E00 Psoriasis universalis res66: psoriasis diagnostic Read
M161F00 Psoriasis vulgaris res66: psoriasis diagnostic Read
M161F11 Chronic large plaque psoriasis res66: psoriasis diagnostic Read
M161H00 Erythrodermic psoriasis res66: psoriasis diagnostic Read
M161z00 Psoriasis NOS res66: psoriasis diagnostic Read
M16y.00 Other psoriasis and similar disorders res66: psoriasis diagnostic Read
M16y000 Scalp psoriasis res66: psoriasis diagnostic Read
M16z.00 Psoriasis and similar disorders NOS res66: psoriasis diagnostic Read
Myu3000 [X]Other psoriasis res66: psoriasis diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH912/version/1903/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH912/version/1903/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH912', '1903', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH912/version/1903/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH912/version/1903/export/codes/?format=json
CSV site_root/phenotypes/PH912/version/1903/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH912', '1903', api_client=client)

Version History

Version
ID
Name Owner Publish date
1903 Psoriasis ieuan.scanlon 2022-04-04 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

Print - Print page.