Purpose:
This is a retrospective cohort study using observational data from anonymised primary care records. We identify and extract all patients with type 2 diabetes and associated clinical data from the Clinical Practice Research Datalink (CPRD) to inform models of disease progression and stratification of treatment.
Participants:
Data were extracted from CPRD on 8 August 2016. The initial data set contained all patients (n=313 485) in the database who had received a type 2 diabetes medication. Criteria were applied to identify and exclude those with type 1 diabetes, polycystic ovarian syndrome or other forms of diabetes (n=40 204), and for data quality control (n=12). We identified 251 338 patients for inclusion in future analyses of diabetes progression and treatment response.
Findings to date:
For 6-month response to treatment, measured by change in glycated haemoglobin (HbA1c), we have 91 765 patients with 119 785 treatment response episodes. The greatest impact on reduction of HbA1c occurs with first-line and second-line treatments, metformin and sulfonylurea. Patients moving to thirdline treatments tend to have greater weights and higher body mass index. We have investigated the impact of non-adherence to commonly used glucose-lowering medications on HbA1c. For baseline-adjusted HbA1c change over 1 year, non-adherent patients had lower HbA1c reductions than adherent patients, with mean and 95% CI of −4.4 (−4.7 to −4.0) mmol/mol (−0.40 (−0.43 to −0.37) %).
Future plans:
Findings from studies using these data will help inform future treatment plans and guidelines. Additional data are added with updates from CPRD. This will increase the numbers of patients on newer medications and add more data on those already receiving treatment. There are several ongoing studies investigating different hypotheses regarding differential response to treatment and progression of diabetes. For side effects, links to Hospital Episode Statistics data, where severe events such as hypoglycaemia will be recorded, will also be explored.
Lauren L Rodgers, Michael N Weedon, William E Henley, Andrew T Hattersley, Beverley M Shields, Cohort profile for the MASTERMIND study using the Clinical Practice Research Datalink (CPRD) to investigate stratification of response to treatment in patients with type 2 diabetes. BMJ Open, 7:e017989, 2017.
| Code | Description | Entity type | Category | Coding System (Read) |
|---|---|---|---|---|
| 1154200 | No significant family history of diabetes | res62: diagnostic_codes | diagnostic | Read |
| 1228 | No family history diabetes | res62: diagnostic_codes | diagnostic | Read |
| 1252 | FH: Diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| 1252000 | Family history of diabetes mellitus type 1 | res62: diagnostic_codes | diagnostic | Read |
| 1252100 | Family history of diabetes mellitus type 2 | res62: diagnostic_codes | diagnostic | Read |
| 1252111 | Family history of diabetes mellitus type II | res62: diagnostic_codes | diagnostic | Read |
| 1253 | FH: Diabetes mellitus in first degree relative | res62: diagnostic_codes | diagnostic | Read |
| 12G2.00 | FH: Diabetes in pregnancy | res62: diagnostic_codes | diagnostic | Read |
| 13AB.00 | Diabetic lipid lowering diet | res62: diagnostic_codes | diagnostic | Read |
| 13AC.00 | Diabetic weight reducing diet | res62: diagnostic_codes | diagnostic | Read |
| 13B1.00 | Diabetic diet | res62: diagnostic_codes | diagnostic | Read |
| 13B1000 | Diabetic carbohydrate counting diet | res62: diagnostic_codes | diagnostic | Read |
| 13L4.11 | Diabetic child | res62: diagnostic_codes | diagnostic | Read |
| 13LZ.11 | Diabetic relative | res62: diagnostic_codes | diagnostic | Read |
| 13Y1.00 | Diabetic association member | res62: diagnostic_codes | diagnostic | Read |
| 1434 | H/O: diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| 14F4.00 | H/O: Admission in last year for diabetes foot prob | res62: diagnostic_codes | diagnostic | Read |
| 14O8.00 | At risk of diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| 14O8000 | High risk of diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| 1I0..00 | Diabetes mellitus excluded | res62: diagnostic_codes | diagnostic | Read |
| 1IA..00 | No evidence of diabetic nephropathy | res62: diagnostic_codes | diagnostic | Read |
| 1JL..00 | Suspected diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| 1M8..00 | Diabetic peripheral neuropathic pain | res62: diagnostic_codes | diagnostic | Read |
| 2126300 | Diabetes resolved | res62: diagnostic_codes | diagnostic | Read |
| 212H.00 | Diabetes resolved | res62: diagnostic_codes | diagnostic | Read |
| 2BBF.00 | Retinal abnormality - diabetes related | res62: diagnostic_codes | diagnostic | Read |
| 2BBG.00 | Retinal abnormality - non-diabetes | res62: diagnostic_codes | diagnostic | Read |
| 2BBJ.00 | O/E - no right diabetic retinopathy | res62: diagnostic_codes | diagnostic | Read |
| 2BBK.00 | O/E - no left diabetic retinopathy | res62: diagnostic_codes | diagnostic | Read |
| 2BBL.00 | O/E - diabetic maculopathy present both eyes | res62: diagnostic_codes | diagnostic | Read |
| 2BBM.00 | O/E - diabetic maculopathy absent both eyes | res62: diagnostic_codes | diagnostic | Read |
| 2BBP.00 | O/E - right eye background diabetic retinopathy | res62: diagnostic_codes | diagnostic | Read |
| 2BBQ.00 | O/E - left eye background diabetic retinopathy | res62: diagnostic_codes | diagnostic | Read |
| 2BBR.00 | O/E - right eye preproliferative diabetic retinopa | res62: diagnostic_codes | diagnostic | Read |
| 2BBS.00 | O/E - left eye preproliferative diabetic retinopat | res62: diagnostic_codes | diagnostic | Read |
| 2BBT.00 | O/E - right eye proliferative diabetic retinopathy | res62: diagnostic_codes | diagnostic | Read |
| 2BBV.00 | O/E - left eye proliferative diabetic retinopathy | res62: diagnostic_codes | diagnostic | Read |
| 2BBW.00 | O/E - right eye diabetic maculopathy | res62: diagnostic_codes | diagnostic | Read |
| 2BBX.00 | O/E - left eye diabetic maculopathy | res62: diagnostic_codes | diagnostic | Read |
| 2BBk.00 | O/E - right eye stable treated prolif diabetic ret | res62: diagnostic_codes | diagnostic | Read |
| 2BBl.00 | O/E - left eye stable treated prolif diabetic reti | res62: diagnostic_codes | diagnostic | Read |
| 2BBo.00 | O/E - sight threatening diabetic retinopathy | res62: diagnostic_codes | diagnostic | Read |
| 2BBr.00 | Impaired vision due to diabetic retinopathy | res62: diagnostic_codes | diagnostic | Read |
| 2G51000 | Foot abnormality - diabetes related | res62: diagnostic_codes | diagnostic | Read |
| 2G51100 | Foot abnormality - non-diabetes | res62: diagnostic_codes | diagnostic | Read |
| 2G5A.00 | O/E - Right diabetic foot at risk | res62: diagnostic_codes | diagnostic | Read |
| 2G5B.00 | O/E - Left diabetic foot at risk | res62: diagnostic_codes | diagnostic | Read |
| 2G5C.00 | Foot abnormality - diabetes related | res62: diagnostic_codes | diagnostic | Read |
| 2G5D.00 | Foot abnormality - non-diabetes | res62: diagnostic_codes | diagnostic | Read |
| 2G5E.00 | O/E - Right diabetic foot at low risk | res62: diagnostic_codes | diagnostic | Read |
| 2G5F.00 | O/E - Right diabetic foot at moderate risk | res62: diagnostic_codes | diagnostic | Read |
| 2G5G.00 | O/E - Right diabetic foot at high risk | res62: diagnostic_codes | diagnostic | Read |
| 2G5H.00 | O/E - Right diabetic foot - ulcerated | res62: diagnostic_codes | diagnostic | Read |
| 2G5I.00 | O/E - Left diabetic foot at low risk | res62: diagnostic_codes | diagnostic | Read |
| 2G5J.00 | O/E - Left diabetic foot at moderate risk | res62: diagnostic_codes | diagnostic | Read |
| 2G5K.00 | O/E - Left diabetic foot at high risk | res62: diagnostic_codes | diagnostic | Read |
| 2G5L.00 | O/E - Left diabetic foot - ulcerated | res62: diagnostic_codes | diagnostic | Read |
| 2G5V.00 | O/E - right chronic diabetic foot ulcer | res62: diagnostic_codes | diagnostic | Read |
| 2G5W.00 | O/E - left chronic diabetic foot ulcer | res62: diagnostic_codes | diagnostic | Read |
| 2G5d.00 | O/E - Left diabetic foot at increased risk | res62: diagnostic_codes | diagnostic | Read |
| 2G5e.00 | O/E - Right diabetic foot at increased risk | res62: diagnostic_codes | diagnostic | Read |
| 3881 | Education score - diabetes | res62: diagnostic_codes | diagnostic | Read |
| 3882 | Diabetes well being questionnaire | res62: diagnostic_codes | diagnostic | Read |
| 3883 | Diabetes treatment satisfaction questionnaire | res62: diagnostic_codes | diagnostic | Read |
| 38DE.00 | Cong heart fail, hypertens, age, diab, stroke 2 ri | res62: diagnostic_codes | diagnostic | Read |
| 38DK.00 | Finnish diabetes risk score | res62: diagnostic_codes | diagnostic | Read |
| 38DM.00 | Age, BP, clinical feat, duration, diabetes 2 strok | res62: diagnostic_codes | diagnostic | Read |
| 38Gj.00 | QDiabetes risk calculator | res62: diagnostic_codes | diagnostic | Read |
| 38Gv.00 | Diabetes UK diabetes risk score | res62: diagnostic_codes | diagnostic | Read |
| 42W..00 | Hb. A1C - diabetic control | res62: diagnostic_codes | diagnostic | Read |
| 42WZ.00 | Hb. A1C - diabetic control NOS | res62: diagnostic_codes | diagnostic | Read |
| 42c..00 | HbA1 - diabetic control | res62: diagnostic_codes | diagnostic | Read |
| 44V3.00 | Glucose tol. test diabetic | res62: diagnostic_codes | diagnostic | Read |
| 46Z0.00 | Urine screening test for diabetes | res62: diagnostic_codes | diagnostic | Read |
| 661M400 | Diabetes self-management plan agreed | res62: diagnostic_codes | diagnostic | Read |
| 661N400 | Diabetes self-management plan review | res62: diagnostic_codes | diagnostic | Read |
| 66A..00 | Diabetic monitoring | res62: diagnostic_codes | diagnostic | Read |
| 66A1.00 | Initial diabetic assessment | res62: diagnostic_codes | diagnostic | Read |
| 66A2.00 | Follow-up diabetic assessment | res62: diagnostic_codes | diagnostic | Read |
| 66A3.00 | Diabetic on diet only | res62: diagnostic_codes | diagnostic | Read |
| 66A4.00 | Diabetic on oral treatment | res62: diagnostic_codes | diagnostic | Read |
| 66A5.00 | Diabetic on insulin | res62: diagnostic_codes | diagnostic | Read |
| 66A8.00 | Has seen dietician - diabetes | res62: diagnostic_codes | diagnostic | Read |
| 66A9.00 | Understands diet - diabetes | res62: diagnostic_codes | diagnostic | Read |
| 66AA.11 | Injection sites - diabetic | res62: diagnostic_codes | diagnostic | Read |
| 66AD.00 | Fundoscopy - diabetic check | res62: diagnostic_codes | diagnostic | Read |
| 66AG.00 | Diabetic drug side effects | res62: diagnostic_codes | diagnostic | Read |
| 66AH.00 | Diabetic treatment changed | res62: diagnostic_codes | diagnostic | Read |
| 66AH200 | Conversion to insulin by diabetes specialist nurse | res62: diagnostic_codes | diagnostic | Read |
| 66AI.00 | Diabetic - good control | res62: diagnostic_codes | diagnostic | Read |
| 66AJ.00 | Diabetic - poor control | res62: diagnostic_codes | diagnostic | Read |
| 66AJ.11 | Unstable diabetes | res62: diagnostic_codes | diagnostic | Read |
| 66AJ100 | Brittle diabetes | res62: diagnostic_codes | diagnostic | Read |
| 66AJz00 | Diabetic - poor control NOS | res62: diagnostic_codes | diagnostic | Read |
| 66AK.00 | Diabetic - cooperative patient | res62: diagnostic_codes | diagnostic | Read |
| 66AL.00 | Diabetic-uncooperative patient | res62: diagnostic_codes | diagnostic | Read |
| 66AM.00 | Diabetic - follow-up default | res62: diagnostic_codes | diagnostic | Read |
| 66AN.00 | Date diabetic treatment start | res62: diagnostic_codes | diagnostic | Read |
| 66AO.00 | Date diabetic treatment stopp. | res62: diagnostic_codes | diagnostic | Read |
| 66AP.00 | Diabetes: practice programme | res62: diagnostic_codes | diagnostic | Read |
| 66AQ.00 | Diabetes: shared care programme | res62: diagnostic_codes | diagnostic | Read |
| 66AQ000 | Unsuitable for diabetes year of care programme | res62: diagnostic_codes | diagnostic | Read |
| 66AQ100 | Declined consent for diabetes year of care program | res62: diagnostic_codes | diagnostic | Read |
| 66AR.00 | Diabetes management plan given | res62: diagnostic_codes | diagnostic | Read |
| 66AS.00 | Diabetic annual review | res62: diagnostic_codes | diagnostic | Read |
| 66AS000 | Diabetes Year of Care annual review | res62: diagnostic_codes | diagnostic | Read |
| 66AT.00 | Annual diabetic blood test | res62: diagnostic_codes | diagnostic | Read |
| 66AU.00 | Diabetes care by hospital only | res62: diagnostic_codes | diagnostic | Read |
| 66AV.00 | Diabetic on insulin and oral treatment | res62: diagnostic_codes | diagnostic | Read |
| 66AW.00 | Diabetic foot risk assessment | res62: diagnostic_codes | diagnostic | Read |
| 66AX.00 | Diabetes: shared care in pregnancy - diabetol and | res62: diagnostic_codes | diagnostic | Read |
| 66AY.00 | Diabetic diet - good compliance | res62: diagnostic_codes | diagnostic | Read |
| 66AZ.00 | Diabetic monitoring NOS | res62: diagnostic_codes | diagnostic | Read |
| 66Aa.00 | Diabetic diet - poor compliance | res62: diagnostic_codes | diagnostic | Read |
| 66Ab.00 | Diabetic foot examination | res62: diagnostic_codes | diagnostic | Read |
| 66Ac.00 | Diabetic peripheral neuropathy screening | res62: diagnostic_codes | diagnostic | Read |
| 66Af.00 | Patient diabetes education review | res62: diagnostic_codes | diagnostic | Read |
| 66Ai.00 | Diabetic 6 month review | res62: diagnostic_codes | diagnostic | Read |
| 66Ak.00 | Diabetic monitoring - lower risk albumin excretion | res62: diagnostic_codes | diagnostic | Read |
| 66Al.00 | Diabetic monitoring - higher risk albumin excretio | res62: diagnostic_codes | diagnostic | Read |
| 66An.00 | Diabetes type 1 review | res62: diagnostic_codes | diagnostic | Read |
| 66Ao.00 | Diabetes type 2 review | res62: diagnostic_codes | diagnostic | Read |
| 66Aq.00 | Diabetic foot screen | res62: diagnostic_codes | diagnostic | Read |
| 66As.00 | Diabetic on subcutaneous treatment | res62: diagnostic_codes | diagnostic | Read |
| 66At.00 | Diabetic dietary review | res62: diagnostic_codes | diagnostic | Read |
| 66At000 | Type I diabetic dietary review | res62: diagnostic_codes | diagnostic | Read |
| 66At011 | Type 1 diabetic dietary review | res62: diagnostic_codes | diagnostic | Read |
| 66At100 | Type II diabetic dietary review | res62: diagnostic_codes | diagnostic | Read |
| 66At111 | Type 2 diabetic dietary review | res62: diagnostic_codes | diagnostic | Read |
| 66Au.00 | Diabetic erectile dysfunction review | res62: diagnostic_codes | diagnostic | Read |
| 66Av.00 | Diabetic assessment of erectile dysfunction | res62: diagnostic_codes | diagnostic | Read |
| 66Az.00 | High risk of diabetes mellitus annual review | res62: diagnostic_codes | diagnostic | Read |
| 66b1.00 | Diabetic monitoring not required | res62: diagnostic_codes | diagnostic | Read |
| 66o..00 | Further diabetic monitoring | res62: diagnostic_codes | diagnostic | Read |
| 66o1.00 | Enquiry about diabetic erectile dysfunction declin | res62: diagnostic_codes | diagnostic | Read |
| 66o2.00 | Diabetic on non-insulin injectable medication | res62: diagnostic_codes | diagnostic | Read |
| 66o5.00 | Diabetic on oral treatment and glucagon-like pepti | res62: diagnostic_codes | diagnostic | Read |
| 6761 | Diabetic pre-pregnancy counselling | res62: diagnostic_codes | diagnostic | Read |
| 679L.00 | Health education - diabetes | res62: diagnostic_codes | diagnostic | Read |
| 679L000 | Education in self management of diabetes | res62: diagnostic_codes | diagnostic | Read |
| 679L200 | Education about diabetes and driving | res62: diagnostic_codes | diagnostic | Read |
| 679L211 | Advice about diabetes and driving | res62: diagnostic_codes | diagnostic | Read |
| 679L300 | Diabetic foot care education | res62: diagnostic_codes | diagnostic | Read |
| 679R.00 | Patient offered diabetes structured education prog | res62: diagnostic_codes | diagnostic | Read |
| 679l.00 | Diabetic injection administration education | res62: diagnostic_codes | diagnostic | Read |
| 67D8.00 | Provision of diabetes clinical summary | res62: diagnostic_codes | diagnostic | Read |
| 67H9.00 | Education about lifestyle for risk of diabetes | res62: diagnostic_codes | diagnostic | Read |
| 67HA.00 | Lifestyle education for diabetes | res62: diagnostic_codes | diagnostic | Read |
| 67IJ100 | Pre-conception advice for diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| 67W1.00 | Recommendation self-refer for diabetes structured | res62: diagnostic_codes | diagnostic | Read |
| 6872 | Diabetes mellitus screen | res62: diagnostic_codes | diagnostic | Read |
| 68A7.00 | Diabetic retinopathy screening | res62: diagnostic_codes | diagnostic | Read |
| 68A9.00 | Diabetic retinopathy screening offered | res62: diagnostic_codes | diagnostic | Read |
| 68AB.00 | Diabetic digital retinopathy screening offered | res62: diagnostic_codes | diagnostic | Read |
| 7276 | Pan retinal photocoagulation for diabetes | res62: diagnostic_codes | diagnostic | Read |
| 889A.00 | Diab mellit insulin-glucose infus acute myocardial | res62: diagnostic_codes | diagnostic | Read |
| 8A12.00 | Diabetic crisis monitoring | res62: diagnostic_codes | diagnostic | Read |
| 8A13.00 | Diabetic stabilisation | res62: diagnostic_codes | diagnostic | Read |
| 8B3l.00 | Diabetes medication review | res62: diagnostic_codes | diagnostic | Read |
| 8BL2.00 | Patient on maximal tolerated therapy for diabetes | res62: diagnostic_codes | diagnostic | Read |
| 8CA4100 | Pt advised re diabetic diet | res62: diagnostic_codes | diagnostic | Read |
| 8CE0.00 | Diabetic leaflet given | res62: diagnostic_codes | diagnostic | Read |
| 8CMW700 | Diabetes clinical pathway | res62: diagnostic_codes | diagnostic | Read |
| 8CP2.00 | Transition of diabetes care options discussed | res62: diagnostic_codes | diagnostic | Read |
| 8CR2.00 | Diabetes clinical management plan | res62: diagnostic_codes | diagnostic | Read |
| 8CS0.00 | Diabetes care plan agreed | res62: diagnostic_codes | diagnostic | Read |
| 8H2J.00 | Admit diabetic emergency | res62: diagnostic_codes | diagnostic | Read |
| 8H3O.00 | Non-urgent diabetic admission | res62: diagnostic_codes | diagnostic | Read |
| 8H4F.00 | Referral to diabetologist | res62: diagnostic_codes | diagnostic | Read |
| 8H4e.00 | Referral to diabetes special interest general prac | res62: diagnostic_codes | diagnostic | Read |
| 8H7C.00 | Refer, diabetic liaison nurse | res62: diagnostic_codes | diagnostic | Read |
| 8H7f.00 | Referral to diabetes nurse | res62: diagnostic_codes | diagnostic | Read |
| 8H7r.00 | Refer to diabetic foot screener | res62: diagnostic_codes | diagnostic | Read |
| 8HBG.00 | Diabetic retinopathy 12 month review | res62: diagnostic_codes | diagnostic | Read |
| 8HBH.00 | Diabetic retinopathy 6 month review | res62: diagnostic_codes | diagnostic | Read |
| 8HHy.00 | Referral to diabetic register | res62: diagnostic_codes | diagnostic | Read |
| 8HKE.00 | Diabetology D.V. requested | res62: diagnostic_codes | diagnostic | Read |
| 8HLE.00 | Diabetology D.V. done | res62: diagnostic_codes | diagnostic | Read |
| 8HME.00 | Listed for Diabetology admissn | res62: diagnostic_codes | diagnostic | Read |
| 8HTE100 | Referral to community diabetes clinic | res62: diagnostic_codes | diagnostic | Read |
| 8HTe.00 | Referral to diabetes preconception counselling cli | res62: diagnostic_codes | diagnostic | Read |
| 8HTi.00 | Referral to multidisciplinary diabetic clinic | res62: diagnostic_codes | diagnostic | Read |
| 8HTk.00 | Referral to diabetic eye clinic | res62: diagnostic_codes | diagnostic | Read |
| 8HVU.00 | Private referral to diabetologist | res62: diagnostic_codes | diagnostic | Read |
| 8Hg4.00 | Discharged from care of diabetes specialist nurse | res62: diagnostic_codes | diagnostic | Read |
| 8HgC.00 | Discharged from diabetes shared care programme | res62: diagnostic_codes | diagnostic | Read |
| 8Hj0.00 | Referral to diabetes structured education programm | res62: diagnostic_codes | diagnostic | Read |
| 8Hj1.00 | Family/carer referral to diabetes structured educa | res62: diagnostic_codes | diagnostic | Read |
| 8Hj3.00 | Referral to DAFNE diabetes structured education pr | res62: diagnostic_codes | diagnostic | Read |
| 8Hj4.00 | Referral to DESMOND diabetes structured education | res62: diagnostic_codes | diagnostic | Read |
| 8Hj5.00 | Referral to XPERT diabetes structured education pr | res62: diagnostic_codes | diagnostic | Read |
| 8Hl1.00 | Referral for diabetic retinopathy screening | res62: diagnostic_codes | diagnostic | Read |
| 8Hl4.00 | Referral to community diabetes specialist nurse | res62: diagnostic_codes | diagnostic | Read |
| 8Hlc.00 | Referral to community diabetes service | res62: diagnostic_codes | diagnostic | Read |
| 8I3W.00 | Diabetic foot examination declined | res62: diagnostic_codes | diagnostic | Read |
| 8I3X.00 | Diabetic retinopathy screening refused | res62: diagnostic_codes | diagnostic | Read |
| 8I57.00 | Patient held diabetic record declined | res62: diagnostic_codes | diagnostic | Read |
| 8I6F.00 | Diabetic retinopathy screening not indicated | res62: diagnostic_codes | diagnostic | Read |
| 8I6G.00 | Diabetic foot examination not indicated | res62: diagnostic_codes | diagnostic | Read |
| 8I81.00 | Did not complete diabetes structured education pro | res62: diagnostic_codes | diagnostic | Read |
| 8I82.00 | Did not complete DAFNE diabetes structured educati | res62: diagnostic_codes | diagnostic | Read |
| 8I83.00 | Did not complete DESMOND diabetes structured educa | res62: diagnostic_codes | diagnostic | Read |
| 8I84.00 | Did not complete XPERT diabetes structured educati | res62: diagnostic_codes | diagnostic | Read |
| 8I94.00 | Diabetes structured education programme not availa | res62: diagnostic_codes | diagnostic | Read |
| 8IAs.00 | Diabetic dietary review declined | res62: diagnostic_codes | diagnostic | Read |
| 8IE2.00 | Diabetes care plan declined | res62: diagnostic_codes | diagnostic | Read |
| 8IEQ.00 | Referral to community diabetes specialist nurse de | res62: diagnostic_codes | diagnostic | Read |
| 8IEa.00 | Referral to DAFNE diabetes structured educn prog d | res62: diagnostic_codes | diagnostic | Read |
| 8OA3.00 | Provision of written information about diabetes an | res62: diagnostic_codes | diagnostic | Read |
| 8OAH.00 | Provision of written information about diabetes an | res62: diagnostic_codes | diagnostic | Read |
| 8OAK.00 | Provsn written information about diabetes & high c | res62: diagnostic_codes | diagnostic | Read |
| 918T.00 | Diabetes key contact | res62: diagnostic_codes | diagnostic | Read |
| 9360 | Patient held diabetic record issued | res62: diagnostic_codes | diagnostic | Read |
| 93C4.00 | Patient consent given for addition to diabetic reg | res62: diagnostic_codes | diagnostic | Read |
| 9M00.00 | Informed consent for diabetes national audit | res62: diagnostic_codes | diagnostic | Read |
| 9M10.00 | Informed dissent for diabetes national audit | res62: diagnostic_codes | diagnostic | Read |
| 9N0m.00 | Seen in diabetic nurse consultant clinic | res62: diagnostic_codes | diagnostic | Read |
| 9N0n.00 | Seen in community diabetes specialist clinic | res62: diagnostic_codes | diagnostic | Read |
| 9N0o.00 | Seen in community diabetic specialist nurse clinic | res62: diagnostic_codes | diagnostic | Read |
| 9N1Q.00 | Seen in diabetic clinic | res62: diagnostic_codes | diagnostic | Read |
| 9N1i.00 | Seen in diabetic foot clinic | res62: diagnostic_codes | diagnostic | Read |
| 9N1o.00 | Seen in multidisciplinary diabetic clinic | res62: diagnostic_codes | diagnostic | Read |
| 9N1v.00 | Seen in diabetic eye clinic | res62: diagnostic_codes | diagnostic | Read |
| 9N2d.00 | Seen by diabetologist | res62: diagnostic_codes | diagnostic | Read |
| 9N2i.00 | Seen by diabetic liaison nurse | res62: diagnostic_codes | diagnostic | Read |
| 9N4I.00 | DNA - Did not attend diabetic clinic | res62: diagnostic_codes | diagnostic | Read |
| 9N4p.00 | Did not attend diabetic retinopathy clinic | res62: diagnostic_codes | diagnostic | Read |
| 9NJy.00 | In-house diabetic foot screening | res62: diagnostic_codes | diagnostic | Read |
| 9NM0.00 | Attending diabetes clinic | res62: diagnostic_codes | diagnostic | Read |
| 9NN8.00 | Under care of diabetologist | res62: diagnostic_codes | diagnostic | Read |
| 9NN9.00 | Under care of diabetes specialist nurse | res62: diagnostic_codes | diagnostic | Read |
| 9NND.00 | Under care of diabetic foot screener | res62: diagnostic_codes | diagnostic | Read |
| 9NiA.00 | Did not attend diabetes structured education progr | res62: diagnostic_codes | diagnostic | Read |
| 9NiC.00 | Did not attend DAFNE diabetes structured education | res62: diagnostic_codes | diagnostic | Read |
| 9NiD.00 | Did not attend DESMOND diabetes structured educati | res62: diagnostic_codes | diagnostic | Read |
| 9NiE.00 | Did not attend XPERT diabetes structured education | res62: diagnostic_codes | diagnostic | Read |
| 9NiZ.00 | Did not attend diabetes foot screening | res62: diagnostic_codes | diagnostic | Read |
| 9Nl4.00 | Seen by general practitioner special interest in d | res62: diagnostic_codes | diagnostic | Read |
| 9OL..00 | Diabetes monitoring admin. | res62: diagnostic_codes | diagnostic | Read |
| 9OL..11 | Diabetes clinic administration | res62: diagnostic_codes | diagnostic | Read |
| 9OL1.00 | Attends diabetes monitoring | res62: diagnostic_codes | diagnostic | Read |
| 9OL2.00 | Refuses diabetes monitoring | res62: diagnostic_codes | diagnostic | Read |
| 9OL3.00 | Diabetes monitoring default | res62: diagnostic_codes | diagnostic | Read |
| 9OL4.00 | Diabetes monitoring 1st letter | res62: diagnostic_codes | diagnostic | Read |
| 9OL5.00 | Diabetes monitoring 2nd letter | res62: diagnostic_codes | diagnostic | Read |
| 9OL6.00 | Diabetes monitoring 3rd letter | res62: diagnostic_codes | diagnostic | Read |
| 9OL7.00 | Diabetes monitor.verbal invite | res62: diagnostic_codes | diagnostic | Read |
| 9OL8.00 | Diabetes monitor.phone invite | res62: diagnostic_codes | diagnostic | Read |
| 9OL9.00 | Diabetes monitoring deleted | res62: diagnostic_codes | diagnostic | Read |
| 9OLA.00 | Diabetes monitor. check done | res62: diagnostic_codes | diagnostic | Read |
| 9OLA.11 | Diabetes monitored | res62: diagnostic_codes | diagnostic | Read |
| 9OLB.00 | Attended diabetes structured education programme | res62: diagnostic_codes | diagnostic | Read |
| 9OLC.00 | Family/carer attended diabetes structured educatio | res62: diagnostic_codes | diagnostic | Read |
| 9OLD.00 | Diabetic patient unsuitable for digital retinal ph | res62: diagnostic_codes | diagnostic | Read |
| 9OLF.00 | Diabetes structured education programme completed | res62: diagnostic_codes | diagnostic | Read |
| 9OLG.00 | Attended XPERT diabetes structured education progr | res62: diagnostic_codes | diagnostic | Read |
| 9OLH.00 | Attended DAFNE diabetes structured education progr | res62: diagnostic_codes | diagnostic | Read |
| 9OLJ.00 | DAFNE diabetes structured education programme comp | res62: diagnostic_codes | diagnostic | Read |
| 9OLK.00 | DESMOND diabetes structured education programme co | res62: diagnostic_codes | diagnostic | Read |
| 9OLL.00 | XPERT diabetes structured education programme comp | res62: diagnostic_codes | diagnostic | Read |
| 9OLM.00 | Diabetes structured education programme declined | res62: diagnostic_codes | diagnostic | Read |
| 9OLN.00 | Diabetes monitor invitation by SMS (short message | res62: diagnostic_codes | diagnostic | Read |
| 9OLZ.00 | Diabetes monitoring admin.NOS | res62: diagnostic_codes | diagnostic | Read |
| 9Oy..00 | Diabetes screening administration | res62: diagnostic_codes | diagnostic | Read |
| 9Oy0.00 | Diabetes screening invitation | res62: diagnostic_codes | diagnostic | Read |
| 9Oy0000 | Diabetic foot screening invitation | res62: diagnostic_codes | diagnostic | Read |
| 9Oy0200 | Diabetic foot screening invitation first letter | res62: diagnostic_codes | diagnostic | Read |
| 9Oy0300 | Diabetic foot screening invitation second letter | res62: diagnostic_codes | diagnostic | Read |
| 9Oy0400 | Diabetic foot screening invitation third letter | res62: diagnostic_codes | diagnostic | Read |
| 9b92000 | Diabetic medicine | res62: diagnostic_codes | diagnostic | Read |
| 9h4..00 | Exception reporting: diabetes quality indicators | res62: diagnostic_codes | diagnostic | Read |
| 9h41.00 | Excepted from diabetes qual indicators: Patient un | res62: diagnostic_codes | diagnostic | Read |
| 9h42.00 | Excepted from diabetes quality indicators: Informe | res62: diagnostic_codes | diagnostic | Read |
| 9h43.00 | Excepted from diabetes qual indicators: service un | res62: diagnostic_codes | diagnostic | Read |
| 9m0..00 | Diabetic retinopathy screening administrative stat | res62: diagnostic_codes | diagnostic | Read |
| 9m00.00 | Eligible for diabetic retinopathy screening | res62: diagnostic_codes | diagnostic | Read |
| 9m01.00 | Ineligible for diabetic retinopathy screening | res62: diagnostic_codes | diagnostic | Read |
| 9m02.00 | Eligibility temporarily inactive for diabetic reti | res62: diagnostic_codes | diagnostic | Read |
| 9m03.00 | Eligibility permanently inactive for diabetic reti | res62: diagnostic_codes | diagnostic | Read |
| 9m04.00 | Excluded from diabetic retinopathy screening | res62: diagnostic_codes | diagnostic | Read |
| 9m05.00 | Excluded from diabetic retinopathy screening as mo | res62: diagnostic_codes | diagnostic | Read |
| 9m06.00 | Excluded from diabetic retinopathy screening as de | res62: diagnostic_codes | diagnostic | Read |
| 9m07.00 | Excluded diabetc retinop screen as under care opht | res62: diagnostic_codes | diagnostic | Read |
| 9m08.00 | Excluded from diabetic retinopathy screening as bl | res62: diagnostic_codes | diagnostic | Read |
| 9m09.00 | Excluded from diabetic retinop screen as no longer | res62: diagnostic_codes | diagnostic | Read |
| 9m0A.00 | Declined diabetic retinopathy screening | res62: diagnostic_codes | diagnostic | Read |
| 9m0B.00 | Excluded frm diab retinop screen as no currnt cont | res62: diagnostic_codes | diagnostic | Read |
| 9m0C.00 | Excluded frm diabetic retinopathy screen as termin | res62: diagnostic_codes | diagnostic | Read |
| 9m0D.00 | Excluded from diabetic retinopthy screen as learn | res62: diagnostic_codes | diagnostic | Read |
| 9m0E.00 | Excluded from diabetic retinopathy screen physical | res62: diagnostic_codes | diagnostic | Read |
| C10..00 | Diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| C100.00 | Diabetes mellitus with no mention of complication | res62: diagnostic_codes | diagnostic | Read |
| C100000 | Diabetes mellitus, juvenile type, no mention of co | res62: diagnostic_codes | diagnostic | Read |
| C100011 | Insulin dependent diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| C100100 | Diabetes mellitus, adult onset, no mention of comp | res62: diagnostic_codes | diagnostic | Read |
| C100111 | Maturity onset diabetes | res62: diagnostic_codes | diagnostic | Read |
| C100112 | Non-insulin dependent diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| C100z00 | Diabetes mellitus NOS with no mention of complicat | res62: diagnostic_codes | diagnostic | Read |
| C101.00 | Diabetes mellitus with ketoacidosis | res62: diagnostic_codes | diagnostic | Read |
| C101000 | Diabetes mellitus, juvenile type, with ketoacidosi | res62: diagnostic_codes | diagnostic | Read |
| C101100 | Diabetes mellitus, adult onset, with ketoacidosis | res62: diagnostic_codes | diagnostic | Read |
| C101z00 | Diabetes mellitus NOS with ketoacidosis | res62: diagnostic_codes | diagnostic | Read |
| C102.00 | Diabetes mellitus with hyperosmolar coma | res62: diagnostic_codes | diagnostic | Read |
| C102000 | Diabetes mellitus, juvenile type, with hyperosmola | res62: diagnostic_codes | diagnostic | Read |
| C102100 | Diabetes mellitus, adult onset, with hyperosmolar | res62: diagnostic_codes | diagnostic | Read |
| C102z00 | Diabetes mellitus NOS with hyperosmolar coma | res62: diagnostic_codes | diagnostic | Read |
| C103.00 | Diabetes mellitus with ketoacidotic coma | res62: diagnostic_codes | diagnostic | Read |
| C103000 | Diabetes mellitus, juvenile type, with ketoacidoti | res62: diagnostic_codes | diagnostic | Read |
| C103100 | Diabetes mellitus, adult onset, with ketoacidotic | res62: diagnostic_codes | diagnostic | Read |
| C103z00 | Diabetes mellitus NOS with ketoacidotic coma | res62: diagnostic_codes | diagnostic | Read |
| C104.00 | Diabetes mellitus with renal manifestation | res62: diagnostic_codes | diagnostic | Read |
| C104.11 | Diabetic nephropathy | res62: diagnostic_codes | diagnostic | Read |
| C104000 | Diabetes mellitus, juvenile type, with renal manif | res62: diagnostic_codes | diagnostic | Read |
| C104100 | Diabetes mellitus, adult onset, with renal manifes | res62: diagnostic_codes | diagnostic | Read |
| C104z00 | Diabetes mellitus with nephropathy NOS | res62: diagnostic_codes | diagnostic | Read |
| C105.00 | Diabetes mellitus with ophthalmic manifestation | res62: diagnostic_codes | diagnostic | Read |
| C105000 | Diabetes mellitus, juvenile type, + ophthalmic man | res62: diagnostic_codes | diagnostic | Read |
| C105100 | Diabetes mellitus, adult onset, + ophthalmic manif | res62: diagnostic_codes | diagnostic | Read |
| C105z00 | Diabetes mellitus NOS with ophthalmic manifestatio | res62: diagnostic_codes | diagnostic | Read |
| C106.00 | Diabetes mellitus with neurological manifestation | res62: diagnostic_codes | diagnostic | Read |
| C106.11 | Diabetic amyotrophy | res62: diagnostic_codes | diagnostic | Read |
| C106.12 | Diabetes mellitus with neuropathy | res62: diagnostic_codes | diagnostic | Read |
| C106.13 | Diabetes mellitus with polyneuropathy | res62: diagnostic_codes | diagnostic | Read |
| C106000 | Diabetes mellitus, juvenile, + neurological manife | res62: diagnostic_codes | diagnostic | Read |
| C106100 | Diabetes mellitus, adult onset, + neurological man | res62: diagnostic_codes | diagnostic | Read |
| C106z00 | Diabetes mellitus NOS with neurological manifestat | res62: diagnostic_codes | diagnostic | Read |
| C107.00 | Diabetes mellitus with peripheral circulatory diso | res62: diagnostic_codes | diagnostic | Read |
| C107.11 | Diabetes mellitus with gangrene | res62: diagnostic_codes | diagnostic | Read |
| C107.12 | Diabetes with gangrene | res62: diagnostic_codes | diagnostic | Read |
| C107000 | Diabetes mellitus, juvenile +peripheral circulator | res62: diagnostic_codes | diagnostic | Read |
| C107100 | Diabetes mellitus, adult, + peripheral circulatory | res62: diagnostic_codes | diagnostic | Read |
| C107200 | Diabetes mellitus, adult with gangrene | res62: diagnostic_codes | diagnostic | Read |
| C107z00 | Diabetes mellitus NOS with peripheral circulatory | res62: diagnostic_codes | diagnostic | Read |
| C108.00 | Insulin dependent diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| C108.11 | IDDM-Insulin dependent diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| C108.12 | Type 1 diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| C108.13 | Type I diabetes mellitus | res62: diagnostic_codes | diagnostic | Read |
| C108000 | Insulin-dependent diabetes mellitus with renal com | res62: diagnostic_codes | diagnostic | Read |
| C108011 | Type I diabetes mellitus with renal complications | res62: diagnostic_codes | diagnostic | Read |
| C108012 | Type 1 diabetes mellitus with renal complications | res62: diagnostic_codes | diagnostic |