BACKGROUND:
With recent changes in the United Kingdom’s clinical practice for diabetes mellitus care, contemporary estimates of sex disparities in cardiovascular risk and risk factor management are needed.
METHODS:
In this retrospective cohort study, using the Clinical Practice Research Datalink linked to hospital and death records for people in England, we identified 79 985 patients with incident type 2 diabetes mellitus (T2DM) between 2006 to 2013 matched to 386 547 patients without diabetes mellitus. Sex-stratified Cox models were used to assess cardiovascular risk.
RESULTS:
Compared with women without T2DM, women with T2DM had a higher cardiovascular event risk (adjusted hazard ratio, 1.20 [95% confidence interval, 1.12–1.28]) with similar corresponding data in men (hazard ratio, 1.12 [1.06–1.19]), leading to a nonsignificant higher relative risk in women (risk ratio, 1.07 [0.98–1.17]). However, some important sex differences in the management of risk factors were observed. Compared with men with T2DM, women with T2DM were more likely to be obese, hypertensive, and have hypercholesterolemia, but were less likely to be prescribed lipid-lowering medication and angiotensin-converting enzyme inhibitors, especially if they had cardiovascular disease.
CONCLUSIONS:
Compared with men developing T2DM, women with T2DM do not have a significantly higher relative increase in cardiovascular risk, but ongoing sex disparities in prescribing should prompt heightened efforts to improve the standard and equity of diabetes mellitus care in women and men.
Alison K Wright,Evangelos Kontopantelis, Richard Emsley, Ian Buchan, Mamas A Mamas, Naveed Sattar, Darren M Ashcroft, Martin K Rutter, , Cardiovascular Risk and Risk Factor Management in Type 2 Diabetes Mellitus A Population-Based Cohort Study Assessing Sex Disparities. Circulation, 139:2742-2753, 2019.
Code | Description | Entity type | Coding System (CPRD_product_code) | Category |
---|---|---|---|---|
1006 | HALF-INDERAL LA capsules 80mg [ASTRAZENEC] | res72: Antihypertensives | CPRD_product_code | drug |
10066 | TOREM tablets 5mg [MEDA] | res72: Antihypertensives | CPRD_product_code | drug |
10088 | DOXADURA tablets 4mg [DISCOVERY] | res72: Antihypertensives | CPRD_product_code | drug |
10135 | NIFEDIPRESS MR modified release tablet 10mg [SANDOZ] | res72: Antihypertensives | CPRD_product_code | drug |
10136 | NIFEDIPRESS MR modified release tablet 20mg [DEXCEL] | res72: Antihypertensives | CPRD_product_code | drug |
10153 | FELENDIL XL modified release tablet 5mg [RATIOPHARM] | res72: Antihypertensives | CPRD_product_code | drug |
10191 | ATENIX tablets 50mg [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
1021 | INNOZIDE tablets [M S D] | res72: Antihypertensives | CPRD_product_code | drug |
10214 | spironolactone suspension sugar-free 5mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
10246 | ADIPINE XL tablets 60mg [CHIESI] | res72: Antihypertensives | CPRD_product_code | drug |
10267 | ADIZEM XL capsules 200mg [NAPPPHARM] | res72: Antihypertensives | CPRD_product_code | drug |
10316 | COAPROVEL tablets 150mg + 12.5mg [SANOFI BMS] | res72: Antihypertensives | CPRD_product_code | drug |
10323 | losartan with hydrochlorothiazide tablets 100mg + 25mg | res72: Antihypertensives | CPRD_product_code | drug |
10392 | LASIX tablets 500mg [BORG] | res72: Antihypertensives | CPRD_product_code | drug |
10429 | LOPRESOR tablets 50mg [NOVARTIS] | res72: Antihypertensives | CPRD_product_code | drug |
10595 | NIMOTOP tablets 30mg [BAYER] | res72: Antihypertensives | CPRD_product_code | drug |
1060 | amiloride hydrochloride tablets 5mg | res72: Antihypertensives | CPRD_product_code | drug |
10627 | CO-BETALOC tablets 100mg + 12.5mg [PHARMACIA] | res72: Antihypertensives | CPRD_product_code | drug |
10716 | CORGARD tablets 80mg [SANOFI/AVE] | res72: Antihypertensives | CPRD_product_code | drug |
10777 | TRASICOR tablets 160mg [NOVARTIS] | res72: Antihypertensives | CPRD_product_code | drug |
10781 | LASIX + K tablets [HOECHSTMAR] | res72: Antihypertensives | CPRD_product_code | drug |
10882 | CARACE tablets 2.5mg [BMS] | res72: Antihypertensives | CPRD_product_code | drug |
10892 | EMCOR tablets 10mg [MERCK SER] | res72: Antihypertensives | CPRD_product_code | drug |
10902 | captopril with hydrochlorothiazide tablets 50mg + 25mg | res72: Antihypertensives | CPRD_product_code | drug |
11133 | hydrochlorothiazide with captopril tablets 25mg + 50mg | res72: Antihypertensives | CPRD_product_code | drug |
11156 | SPIROLONE tablets 25mg [BERK] | res72: Antihypertensives | CPRD_product_code | drug |
11197 | INNOVACE MELT wafer 5mg [M S D] | res72: Antihypertensives | CPRD_product_code | drug |
1121 | captopril tablets 12.5mg | res72: Antihypertensives | CPRD_product_code | drug |
11223 | ANGITIL SR capsules 90mg [CHIESI] | res72: Antihypertensives | CPRD_product_code | drug |
1124 | TENORETIC tablets 100mg + 25mg [ASTRAZENEC] | res72: Antihypertensives | CPRD_product_code | drug |
1125 | NAVIDREX -K tablets [NOV/CIBA] | res72: Antihypertensives | CPRD_product_code | drug |
11251 | DIOVAN capsules 40mg [NOVARTIS] | res72: Antihypertensives | CPRD_product_code | drug |
11252 | DIOVAN capsules 80mg [NOVARTIS] | res72: Antihypertensives | CPRD_product_code | drug |
11265 | triamterene with furosemide tablets 50mg + 40mg | res72: Antihypertensives | CPRD_product_code | drug |
11268 | TOREM tablets 2.5mg [MEDA] | res72: Antihypertensives | CPRD_product_code | drug |
1130 | VIAZEM XL capsules 300mg [GENUS] | res72: Antihypertensives | CPRD_product_code | drug |
11338 | bendroflumethiazide with nadolol tablets 5mg + 40mg | res72: Antihypertensives | CPRD_product_code | drug |
11348 | APROVEL tablets 300mg [SANOFI/AVE] | res72: Antihypertensives | CPRD_product_code | drug |
11351 | co-zidocapt (hydrochlorothiazide and captopril) tablets 25mg + 50mg | res72: Antihypertensives | CPRD_product_code | drug |
11384 | co-flumactone (hydroflumethiazide and spironolactone) tablets 50mg+50mg | res72: Antihypertensives | CPRD_product_code | drug |
11394 | BARATOL tablets 25mg [SHIRE] | res72: Antihypertensives | CPRD_product_code | drug |
1143 | captopril tablets 25mg | res72: Antihypertensives | CPRD_product_code | drug |
1144 | CAPOTEN tablets 25mg [SQUIBB] | res72: Antihypertensives | CPRD_product_code | drug |
11448 | irbesartan with hydrochlorothiazide tablets 150mg + 12.5mg | res72: Antihypertensives | CPRD_product_code | drug |
11469 | irbesartan with hydrochlorothiazide tablets 300mg + 12.5mg | res72: Antihypertensives | CPRD_product_code | drug |
11487 | torasemide tablets 2.5mg | res72: Antihypertensives | CPRD_product_code | drug |
11512 | NIFEDIPRESS MR modified release tablet 10mg [DEXCEL] | res72: Antihypertensives | CPRD_product_code | drug |
11519 | spironolactone suspension sugar-free 25mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
11526 | COAPROVEL tablets 300mg + 12.5mg [SANOFI BMS] | res72: Antihypertensives | CPRD_product_code | drug |
11547 | nimodipine tablets 30mg | res72: Antihypertensives | CPRD_product_code | drug |
11561 | co-zidocapt (hydrochlorothiazide and captopril) tablets 12.5mg + 25mg | res72: Antihypertensives | CPRD_product_code | drug |
11567 | ramipril with felodipine modified release tablet 5mg + 5mg | res72: Antihypertensives | CPRD_product_code | drug |
11641 | captopril with hydrochlorothiazide tablets 25mg + 12.5mg | res72: Antihypertensives | CPRD_product_code | drug |
1170 | cyclopenthiazide tablets 0.5mg | res72: Antihypertensives | CPRD_product_code | drug |
11769 | CALCHAN MR tablets 20mg [RANBAXY] | res72: Antihypertensives | CPRD_product_code | drug |
11770 | DILZEM SR capsules 60mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
11793 | metoprolol tartrate suspension 50mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
11864 | valsartan with hydrochlorothiazide tablets 160mg + 12.5mg | res72: Antihypertensives | CPRD_product_code | drug |
119 | doxazosin tablets 1mg | res72: Antihypertensives | CPRD_product_code | drug |
11922 | diltiazem oral suspension 60mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
11937 | ramipril oral suspension 2.5mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
11943 | CARDENE capsules 20mg [ASTELLAS] | res72: Antihypertensives | CPRD_product_code | drug |
11965 | ramipril with felodipine modified release tablet 2.5mg + 2.5mg | res72: Antihypertensives | CPRD_product_code | drug |
11966 | MOTENS tablets 2mg [BOEH INGL] | res72: Antihypertensives | CPRD_product_code | drug |
11973 | CALCICARD CR controlled release tablet 120mg [IVAX] | res72: Antihypertensives | CPRD_product_code | drug |
11983 | perindopril erbumine oral suspension 4mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
11987 | lisinopril oral solution 5mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
12037 | BETIM tablets 10mg [ICN] | res72: Antihypertensives | CPRD_product_code | drug |
12054 | propranolol with bendroflumethiazide capsules 80mg + 2.5mg | res72: Antihypertensives | CPRD_product_code | drug |
1209 | NEO-NACLEX tablets 5mg [GOLDSHIELD] | res72: Antihypertensives | CPRD_product_code | drug |
1211 | Bendroflumethiazide 2.5mg / Potassium chloride 630mg (potassium 8.4mmol) modified-release tablets | res72: Antihypertensives | CPRD_product_code | drug |
12110 | hydroflumethiazide tablets 50mg | res72: Antihypertensives | CPRD_product_code | drug |
1213 | Neo-Naclex-K modified-release tablets (Mercury Pharma Group Ltd) | res72: Antihypertensives | CPRD_product_code | drug |
12141 | betaxolol hydrochloride tablets 20mg | res72: Antihypertensives | CPRD_product_code | drug |
12226 | BURINEX oral liquid sugar-free 1mg/5ml [LEO] | res72: Antihypertensives | CPRD_product_code | drug |
12294 | BURINEX tablets 5mg [LEO] | res72: Antihypertensives | CPRD_product_code | drug |
12296 | SECTRAL capsules 100mg [AVENTIS] | res72: Antihypertensives | CPRD_product_code | drug |
12313 | CARACE tablets 20mg [BMS] | res72: Antihypertensives | CPRD_product_code | drug |
12354 | etacrynic acid tablets 50mg | res72: Antihypertensives | CPRD_product_code | drug |
12360 | NEPHRIL tablets 1mg [PFIZER] | res72: Antihypertensives | CPRD_product_code | drug |
12367 | piretanide capsules 6mg | res72: Antihypertensives | CPRD_product_code | drug |
12411 | cilazapril tablets 500 micrograms | res72: Antihypertensives | CPRD_product_code | drug |
12412 | cilazapril tablets 2.5mg | res72: Antihypertensives | CPRD_product_code | drug |
12440 | HYDROSALURIC tablets 25mg [M S D] | res72: Antihypertensives | CPRD_product_code | drug |
12456 | SOTAZIDE tablets [BRISTOL] | res72: Antihypertensives | CPRD_product_code | drug |
1251 | MODURET 25 tablets [M S D] | res72: Antihypertensives | CPRD_product_code | drug |
12517 | timolol maleate with bendroflumethiazide tablets 20mg + 5mg | res72: Antihypertensives | CPRD_product_code | drug |
12518 | HYPOVASE BD starter pack [PFIZER] | res72: Antihypertensives | CPRD_product_code | drug |
12519 | KERLONE tablets 20mg [SANOFI S] | res72: Antihypertensives | CPRD_product_code | drug |
12546 | KALSPARE tablets [DOMINION] | res72: Antihypertensives | CPRD_product_code | drug |
12547 | triamterene with chlortalidone tablets 50mg + 50mg | res72: Antihypertensives | CPRD_product_code | drug |
12574 | cilazapril tablets 1mg | res72: Antihypertensives | CPRD_product_code | drug |
12606 | NIFELEASE modified release tablet 20mg [EASTERN] | res72: Antihypertensives | CPRD_product_code | drug |
12613 | UNIPINE XL modified release tablet 30mg [GENUS] | res72: Antihypertensives | CPRD_product_code | drug |
1262 | nifedipine 12 hour modified release tablets 20mg | res72: Antihypertensives | CPRD_product_code | drug |
12639 | DILTIAZEM HYDROCHLORIDE modified release tablet 90mg [ACTAVIS] | res72: Antihypertensives | CPRD_product_code | drug |
12651 | timolol maleate with bendroflumethiazide tablets 10mg + 2.5mg | res72: Antihypertensives | CPRD_product_code | drug |
12705 | ANGIOZEM CR slow-release tablets 90mg [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
12815 | TANATRIL tablets 10mg [CHIESI] | res72: Antihypertensives | CPRD_product_code | drug |
12836 | eprosartan tablets 600mg | res72: Antihypertensives | CPRD_product_code | drug |
12858 | imidapril hydrochloride tablets 10mg | res72: Antihypertensives | CPRD_product_code | drug |
12874 | telmisartan tablets 80mg | res72: Antihypertensives | CPRD_product_code | drug |
12875 | CARDENE SR capsules 45mg [ASTELLAS] | res72: Antihypertensives | CPRD_product_code | drug |
1288 | TENORET tablets 50mg + 12.5mg [ASTRAZENEC] | res72: Antihypertensives | CPRD_product_code | drug |
1289 | TILDIEM RETARD tablets 120mg [SANOFI/AVE] | res72: Antihypertensives | CPRD_product_code | drug |
1290 | bisoprolol tablets 10mg | res72: Antihypertensives | CPRD_product_code | drug |
1292 | HYPOVASE tablets 1mg [PFIZER] | res72: Antihypertensives | CPRD_product_code | drug |
12926 | polythiazide tablets 1mg | res72: Antihypertensives | CPRD_product_code | drug |
1293 | irbesartan tablets 150mg | res72: Antihypertensives | CPRD_product_code | drug |
1294 | doxazosin tablets 4mg | res72: Antihypertensives | CPRD_product_code | drug |
12946 | spironolactone suspension sugar-free 10mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
1295 | labetalol hydrochloride tablets 400mg | res72: Antihypertensives | CPRD_product_code | drug |
1297 | ALDACTIDE film coated tablets 50mg + 50mg [PHARMACIA] | res72: Antihypertensives | CPRD_product_code | drug |
1299 | enalapril tablets 10mg | res72: Antihypertensives | CPRD_product_code | drug |
1300 | NIFENSAR XL sustained release tablets 20mg [RHONE] | res72: Antihypertensives | CPRD_product_code | drug |
1301 | FRUMIL LS tablets 20mg + 2.5mg [HELIOS] | res72: Antihypertensives | CPRD_product_code | drug |
13026 | cilazapril tablets 5mg | res72: Antihypertensives | CPRD_product_code | drug |
13027 | VIAZEM XL capsules 240mg [GENUS] | res72: Antihypertensives | CPRD_product_code | drug |
13033 | ANGITIL XL capsules 240mg [CHIESI] | res72: Antihypertensives | CPRD_product_code | drug |
13075 | DILZEM XL capsules 180mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
13123 | eprosartan tablets 400mg | res72: Antihypertensives | CPRD_product_code | drug |
13127 | DILZEM XL capsules 240mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
13139 | ADIPINE XL tablets 30mg [CHIESI] | res72: Antihypertensives | CPRD_product_code | drug |
13240 | DILZEM XL capsules 120mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
13243 | lercanidipine hydrochloride tablets 20mg | res72: Antihypertensives | CPRD_product_code | drug |
13246 | chlorothiazide oral suspension 150mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
13264 | spironolactone oral suspension 15mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
13302 | DILZEM SR capsules 90mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
1333 | oxprenolol tablets 40mg | res72: Antihypertensives | CPRD_product_code | drug |
1334 | oxprenolol modified release tablet 160mg | res72: Antihypertensives | CPRD_product_code | drug |
13352 | MIDAMOR tablets 5mg [MSD MORSON] | res72: Antihypertensives | CPRD_product_code | drug |
13363 | ESIDREX tablets 50mg [NOV/CIBA] | res72: Antihypertensives | CPRD_product_code | drug |
13394 | TENORMIN syrup 25mg/5ml [ASTRAZENEC] | res72: Antihypertensives | CPRD_product_code | drug |
13410 | ANGIOZEM tablets 60mg [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
13415 | CORGARD tablets 40mg [SANOFI/AVE] | res72: Antihypertensives | CPRD_product_code | drug |
13435 | FRUMIL forte tablets 80mg + 10mg [HELIOS] | res72: Antihypertensives | CPRD_product_code | drug |
13499 | LOPRESOR tablets 100mg [NOVARTIS] | res72: Antihypertensives | CPRD_product_code | drug |
13525 | HYDRENOX tablets 50mg [KNOLL] | res72: Antihypertensives | CPRD_product_code | drug |
13526 | ATENIXCO tablets 100mg + 25mg [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
13589 | STARIL tablets 20mg [SQUIBB] | res72: Antihypertensives | CPRD_product_code | drug |
13610 | ALPHAVASE tablets 2mg [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
13672 | ANGIOPINE MR modified release tablet 10mg [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
1369 | furosemide with amiloride tablets 40mg + 5mg | res72: Antihypertensives | CPRD_product_code | drug |
13699 | ANGIOPINE LA tablets 40mg [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
13755 | enalapril wafer 10mg | res72: Antihypertensives | CPRD_product_code | drug |
13821 | MICARDIS tablets 40mg [BOEH INGL] | res72: Antihypertensives | CPRD_product_code | drug |
13871 | co-prenozide (oxprenolol and cyclopenthiazide) modified release tablet 160mg + 0.25mg | res72: Antihypertensives | CPRD_product_code | drug |
13926 | diltiazem 24 hour modified release capsules 360mg | res72: Antihypertensives | CPRD_product_code | drug |
14030 | CARDICOR tablets 2.5mg [MERCK SER] | res72: Antihypertensives | CPRD_product_code | drug |
14057 | pindolol with clopamide tablets 10mg + 5mg | res72: Antihypertensives | CPRD_product_code | drug |
14058 | CARDICOR tablets 1.25mg [MERCK SER] | res72: Antihypertensives | CPRD_product_code | drug |
14117 | EUCARDIC tablets 3.125mg [ROCHE] | res72: Antihypertensives | CPRD_product_code | drug |
14126 | acebutolol hydrochloride and hydrochlorothiazide tablets 200mg + 12.5mg | res72: Antihypertensives | CPRD_product_code | drug |
14146 | EUCARDIC tablets 6.25mg [ROCHE] | res72: Antihypertensives | CPRD_product_code | drug |
14228 | COVERSYL PLUS tablets [SERVIER] | res72: Antihypertensives | CPRD_product_code | drug |
14283 | valsartan with hydrochlorothiazide tablets 160mg + 25mg | res72: Antihypertensives | CPRD_product_code | drug |
14300 | ZANIDIP tablets 20mg [RECORDATI] | res72: Antihypertensives | CPRD_product_code | drug |
14305 | VASCALPHA prolonged release tablet 10mg [ACTAVIS] | res72: Antihypertensives | CPRD_product_code | drug |
14387 | CARACE tablets 5mg [BMS] | res72: Antihypertensives | CPRD_product_code | drug |
14438 | CORGARETIC 80 tablets [SANOFI S] | res72: Antihypertensives | CPRD_product_code | drug |
14477 | ACCUPRO tablets 10mg [PFIZER] | res72: Antihypertensives | CPRD_product_code | drug |
14478 | ACCUPRO tablets 20mg [PFIZER] | res72: Antihypertensives | CPRD_product_code | drug |
1448 | propranolol modified release capsules 160mg | res72: Antihypertensives | CPRD_product_code | drug |
1449 | nifedipine 24 hour modified release tablets 30mg | res72: Antihypertensives | CPRD_product_code | drug |
1455 | prazosin tablets 500 micrograms | res72: Antihypertensives | CPRD_product_code | drug |
14587 | amiloride hydrochloride with bumetanide tablets 5mg + 1mg | res72: Antihypertensives | CPRD_product_code | drug |
14673 | pindolol tablets 15mg | res72: Antihypertensives | CPRD_product_code | drug |
147 | ramipril capsules 1.25mg | res72: Antihypertensives | CPRD_product_code | drug |
14738 | hydrochlorothiazide with losartan tablets 12.5mg + 50mg | res72: Antihypertensives | CPRD_product_code | drug |
14761 | FRUSID tablets 40mg [DDSA] | res72: Antihypertensives | CPRD_product_code | drug |
14808 | BEDRANOL modified release capsules 80mg [SANDOZ] | res72: Antihypertensives | CPRD_product_code | drug |
14837 | FRUSOL oral solution sugar-free 50mg/5ml [ROSEMONT] | res72: Antihypertensives | CPRD_product_code | drug |
14861 | CALCHAN MR tablets 10mg [RANBAXY] | res72: Antihypertensives | CPRD_product_code | drug |
14870 | telmisartan with hydrochlorothiazide tablets 40mg + 12.5mg | res72: Antihypertensives | CPRD_product_code | drug |
14943 | valsartan tablets 40mg | res72: Antihypertensives | CPRD_product_code | drug |
14960 | COVERSYL tablets 8mg [SERVIER] | res72: Antihypertensives | CPRD_product_code | drug |
14965 | COZAAR tablets 100mg [M S D] | res72: Antihypertensives | CPRD_product_code | drug |
14983 | OLMETEC tablets 10mg [DAIIC-SANK] | res72: Antihypertensives | CPRD_product_code | drug |
15031 | ACCURETIC tablets 10mg + 12.5mg [PFIZER] | res72: Antihypertensives | CPRD_product_code | drug |
15042 | TOLERZIDE tablets [BMS] | res72: Antihypertensives | CPRD_product_code | drug |
15052 | SPIROCTAN tablets 50mg [ROCHE] | res72: Antihypertensives | CPRD_product_code | drug |
15085 | INNOVACE titration pack [M S D] | res72: Antihypertensives | CPRD_product_code | drug |
15096 | ACCUPRO tablets 40mg [PFIZER] | res72: Antihypertensives | CPRD_product_code | drug |
15108 | quinapril and hydrochlorothiazide tablets 10mg + 12.5mg | res72: Antihypertensives | CPRD_product_code | drug |
15117 | nifedipine with atenolol capsules 20mg + 50mg | res72: Antihypertensives | CPRD_product_code | drug |
15121 | moexipril hydrochloride tablets 7.5mg | res72: Antihypertensives | CPRD_product_code | drug |
15127 | hydrochlorothiazide with triamterene tablets 25mg+50mg | res72: Antihypertensives | CPRD_product_code | drug |
15135 | hydrochlorothiazide with captopril tablets 12.5mg + 25mg | res72: Antihypertensives | CPRD_product_code | drug |
15176 | TOTAMOL tablets 50mg [CP PHARM] | res72: Antihypertensives | CPRD_product_code | drug |
1520 | CAPOZIDE tablets [SQUIBB] | res72: Antihypertensives | CPRD_product_code | drug |
15221 | DILCARDIA XL modified release capsules 180mg [GEN (UK)] | res72: Antihypertensives | CPRD_product_code | drug |
15288 | ANGITIL XL capsules 300mg [CHIESI] | res72: Antihypertensives | CPRD_product_code | drug |
1529 | POSICOR tablets 50mg [ROCHE] | res72: Antihypertensives | CPRD_product_code | drug |
1538 | diltiazem tablets 60mg | res72: Antihypertensives | CPRD_product_code | drug |
15457 | BAYCARON tablets 25mg [BAYER] | res72: Antihypertensives | CPRD_product_code | drug |
15488 | metoprolol tartrate with chlortalidone tablets | res72: Antihypertensives | CPRD_product_code | drug |
15605 | cilazapril tablets 250micrograms | res72: Antihypertensives | CPRD_product_code | drug |
15619 | HALF-BETADUR CR capsules 80mg [MONMOUTH] | res72: Antihypertensives | CPRD_product_code | drug |
15652 | mibefradil tablets 50mg | res72: Antihypertensives | CPRD_product_code | drug |
15715 | GENALAT RETARD modified release tablet 20mg [WYETH PHAR] | res72: Antihypertensives | CPRD_product_code | drug |
15730 | TOTAMOL tablets 100mg [CP PHARM] | res72: Antihypertensives | CPRD_product_code | drug |
15811 | co-flumactone (hydroflumethiazide and spironolactone) tablets 25mg+25mg | res72: Antihypertensives | CPRD_product_code | drug |
15874 | amiloride hydrochloride with furosemide tablets 2.5mg + 20mg | res72: Antihypertensives | CPRD_product_code | drug |
15958 | captopril tablets 2mg | res72: Antihypertensives | CPRD_product_code | drug |
1597 | labetalol hydrochloride tablets 100mg | res72: Antihypertensives | CPRD_product_code | drug |
16038 | DILZEM SR capsules 120mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
16060 | valsartan with hydrochlorothiazide tablets 80mg + 12.5mg | res72: Antihypertensives | CPRD_product_code | drug |
16073 | NIFEDIPRESS MR modified release tablet 10mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
16161 | telmisartan with hydrochlorothiazide tablets 80mg + 12.5mg | res72: Antihypertensives | CPRD_product_code | drug |
16162 | amlodipine oral suspension 5mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
16196 | VASCACE tablets 5mg [ROCHE] | res72: Antihypertensives | CPRD_product_code | drug |
16197 | VASCACE tablets 2.5mg [ROCHE] | res72: Antihypertensives | CPRD_product_code | drug |
16198 | BARATOL tablets 50mg [SHIRE] | res72: Antihypertensives | CPRD_product_code | drug |
16201 | HYTRIN BPH tablets 2mg [AMDIPHARM] | res72: Antihypertensives | CPRD_product_code | drug |
16206 | FROOP 40 tablets 40mg [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
16212 | VASCACE tablets 1mg [ROCHE] | res72: Antihypertensives | CPRD_product_code | drug |
16285 | TEVETEN tablets 400mg [ABBOTT] | res72: Antihypertensives | CPRD_product_code | drug |
16371 | TEVETEN tablets 600mg [ABBOTT] | res72: Antihypertensives | CPRD_product_code | drug |
16498 | KALSPARE tablets [DHP] | res72: Antihypertensives | CPRD_product_code | drug |
16632 | HYDROSALURIC tablets 50mg [M S D] | res72: Antihypertensives | CPRD_product_code | drug |
16645 | LABROCOL tablets 400mg [LAGAP] | res72: Antihypertensives | CPRD_product_code | drug |
16701 | CARACE tablets 10mg [BMS] | res72: Antihypertensives | CPRD_product_code | drug |
16708 | enalapril titration pack | res72: Antihypertensives | CPRD_product_code | drug |
16710 | GOPTEN capsules 0.5mg [ABBOTT] | res72: Antihypertensives | CPRD_product_code | drug |
16776 | CELECTOL tablets 400mg [PANTHEON] | res72: Antihypertensives | CPRD_product_code | drug |
16786 | chlortalidone with atenolol tablets 25mg+100mg | res72: Antihypertensives | CPRD_product_code | drug |
1684 | BETA-ADALAT capsules 50mg + 20mg [BAYER] | res72: Antihypertensives | CPRD_product_code | drug |
16850 | ANGIOZEM CR slow-release tablets 120mg [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
1686 | diltiazem 12 hour modified release capsules 90mg | res72: Antihypertensives | CPRD_product_code | drug |
16924 | imidapril hydrochloride tablets 5mg | res72: Antihypertensives | CPRD_product_code | drug |
17006 | TRIAPIN modified release tablet 5mg + 5mg [SANOFI/AVE] | res72: Antihypertensives | CPRD_product_code | drug |
17120 | moexipril hydrochloride tablets 15mg | res72: Antihypertensives | CPRD_product_code | drug |
17143 | mefruside tablets 25mg | res72: Antihypertensives | CPRD_product_code | drug |
17149 | MONOZIDE 10 tablets 10mg + 6.25mg [WYETH PHAR] | res72: Antihypertensives | CPRD_product_code | drug |
1721 | DYAZIDE tablets [MERCURY] | res72: Antihypertensives | CPRD_product_code | drug |
17252 | ESIDREX tablets 25mg [NOV/CIBA] | res72: Antihypertensives | CPRD_product_code | drug |
17322 | ATENIX tablets 25mg [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
17325 | CARDILATE MR tablets 10mg [IVAX] | res72: Antihypertensives | CPRD_product_code | drug |
17338 | NIFEDOTARD 20 MR modified release tablet 20mg [GALEN] | res72: Antihypertensives | CPRD_product_code | drug |
17342 | NIVATEN RETARD modified release tablet 10mg [ACTAVIS] | res72: Antihypertensives | CPRD_product_code | drug |
17406 | ZEMTARD XL capsules 180mg [GALEN] | res72: Antihypertensives | CPRD_product_code | drug |
17425 | ZEMTARD XL capsules 120mg [GALEN] | res72: Antihypertensives | CPRD_product_code | drug |
17448 | NIFEDIPRESS MR modified release tablet 10mg [STERWIN] | res72: Antihypertensives | CPRD_product_code | drug |
17462 | bisoprolol and hydrochlorothiazide tablets 10mg + 6.25mg | res72: Antihypertensives | CPRD_product_code | drug |
17474 | felodipine with ramipril modified release tablet 5mg + 5mg | res72: Antihypertensives | CPRD_product_code | drug |
17492 | ZEMTARD XL capsules 300mg [GALEN] | res72: Antihypertensives | CPRD_product_code | drug |
17545 | MICARDIS tablets 80mg [BOEH INGL] | res72: Antihypertensives | CPRD_product_code | drug |
17557 | FELOTENS XL tablets 5mg [GENUS] | res72: Antihypertensives | CPRD_product_code | drug |
17561 | bendroflumethiazide with potassium modified release tablet 2.5mg + 7.7mmol | res72: Antihypertensives | CPRD_product_code | drug |
17566 | FELOTENS XL tablets 10mg [GENUS] | res72: Antihypertensives | CPRD_product_code | drug |
17586 | SLOZEM capsules 300mg [MERCK SER] | res72: Antihypertensives | CPRD_product_code | drug |
17615 | CARDICOR tablets 5mg [MERCK SER] | res72: Antihypertensives | CPRD_product_code | drug |
17624 | captopril oral suspension 5mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
17633 | captopril oral liquid 3mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
17640 | AMLOSTIN tablets 5mg [DISCOVERY] | res72: Antihypertensives | CPRD_product_code | drug |
17655 | CARACE 10 plus tablets [BMS] | res72: Antihypertensives | CPRD_product_code | drug |
17666 | VIAZEM XL capsules 180mg [GENUS] | res72: Antihypertensives | CPRD_product_code | drug |
17686 | MICARDIS tablets 20mg [BOEH INGL] | res72: Antihypertensives | CPRD_product_code | drug |
17689 | MICARDIS PLUS tablets 80mg + 12.5mg [BOEH INGL] | res72: Antihypertensives | CPRD_product_code | drug |
17720 | SALURIC tablets 500mg [M S D] | res72: Antihypertensives | CPRD_product_code | drug |
1776 | BURINEX K tablets 500micrograms + 7.7mmol [LEO] | res72: Antihypertensives | CPRD_product_code | drug |
17783 | SPIROPROP tablets [PHARMACIA] | res72: Antihypertensives | CPRD_product_code | drug |
1780 | losartan tablets 50mg | res72: Antihypertensives | CPRD_product_code | drug |
1788 | atenolol with chlortalidone tablets 100mg+25mg | res72: Antihypertensives | CPRD_product_code | drug |
17950 | SPIROLONE tablets 50mg [BERK] | res72: Antihypertensives | CPRD_product_code | drug |
17960 | furosemide with potassium tablets 20mg + 10mmol | res72: Antihypertensives | CPRD_product_code | drug |
18038 | nisoldipine modified release tablet 20mg | res72: Antihypertensives | CPRD_product_code | drug |
1807 | captopril tablets 50mg | res72: Antihypertensives | CPRD_product_code | drug |
18096 | torasemide tablets 10mg | res72: Antihypertensives | CPRD_product_code | drug |
18185 | CARDICOR tablets 7.5mg [MERCK SER] | res72: Antihypertensives | CPRD_product_code | drug |
18200 | olmesartan medoxomil with hydrochlorothiazide tablets 20mg + 12.5mg | res72: Antihypertensives | CPRD_product_code | drug |
18202 | MICARDIS PLUS tablets 40mg + 12.5mg [BOEH INGL] | res72: Antihypertensives | CPRD_product_code | drug |
18219 | imidapril hydrochloride tablets 20mg | res72: Antihypertensives | CPRD_product_code | drug |
18223 | trandolapril with verapamil modified release capsules 2mg + 180mg | res72: Antihypertensives | CPRD_product_code | drug |
18263 | ACEZIDE tablets [SQUIBB] | res72: Antihypertensives | CPRD_product_code | drug |
18267 | ENDURON tablets 5mg [ABBOTT] | res72: Antihypertensives | CPRD_product_code | drug |
18269 | ACEPRIL tablets 12.5mg [SQUIBB] | res72: Antihypertensives | CPRD_product_code | drug |
18287 | CO-BETALOC SA tablets 200mg + 25mg [PHARMACIA] | res72: Antihypertensives | CPRD_product_code | drug |
18325 | ACEPRIL tablets 50mg [SQUIBB] | res72: Antihypertensives | CPRD_product_code | drug |
18332 | ARIDIL tablets 20mg + 2.5mg [CP PHARM] | res72: Antihypertensives | CPRD_product_code | drug |
1836 | diltiazem 8 hour modified release tablets 60mg | res72: Antihypertensives | CPRD_product_code | drug |
18361 | AMILMAXCO tablets [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
18379 | DILCARDIA SR modified release capsules 90mg [GEN (UK)] | res72: Antihypertensives | CPRD_product_code | drug |
18403 | DILTIAZEM HYDROCHLORIDE modified release capsules 180mg [HILLCROSS] | res72: Antihypertensives | CPRD_product_code | drug |
18404 | DILTIAZEM HYDROCHLORIDE SR capsules 60mg [HILLCROSS] | res72: Antihypertensives | CPRD_product_code | drug |
18414 | EUCARDIC tablets 12.5mg [ROCHE] | res72: Antihypertensives | CPRD_product_code | drug |
18497 | amiloride hydrochloride with furosemide tablets 10mg + 80mg | res72: Antihypertensives | CPRD_product_code | drug |
1854 | ADALAT LA tablets 30mg [BAYER] | res72: Antihypertensives | CPRD_product_code | drug |
18606 | diltiazem and hydrochlorothiazide modified release capsules 150mg + 12.5mg | res72: Antihypertensives | CPRD_product_code | drug |
18650 | EDECRIN tablets 50mg [M S D] | res72: Antihypertensives | CPRD_product_code | drug |
18726 | TRIAMAXCO tablets [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
18733 | co-amilozide (amiloride and hydrochlorothiazide) oral solution 5mg + 50mg/5ml | res72: Antihypertensives | CPRD_product_code | drug |
18743 | TENBEN capsules 25mg + 1.25mg [GALEN] | res72: Antihypertensives | CPRD_product_code | drug |
18830 | DISOGRAM SR capsules 90mg [RANBAXY] | res72: Antihypertensives | CPRD_product_code | drug |
18834 | DISOGRAM SR capsules 60mg [RANBAXY] | res72: Antihypertensives | CPRD_product_code | drug |
18852 | DISOGRAM SR capsules 120mg [RANBAXY] | res72: Antihypertensives | CPRD_product_code | drug |
18874 | DISOGRAM SR capsules 180mg [RANBAXY] | res72: Antihypertensives | CPRD_product_code | drug |
18903 | olmesartan medoxomil with hydrochlorothiazide tablets 20mg + 25mg | res72: Antihypertensives | CPRD_product_code | drug |
18910 | OLMETEC tablets 20mg [DAIIC-SANK] | res72: Antihypertensives | CPRD_product_code | drug |
18950 | TOTAMOL tablets 25mg [CP PHARM] | res72: Antihypertensives | CPRD_product_code | drug |
18973 | CENTYL tablets 2.5mg [BURGESS] | res72: Antihypertensives | CPRD_product_code | drug |
18975 | CALCICARD tablets 60mg [3M] | res72: Antihypertensives | CPRD_product_code | drug |
19013 | CLINIUM tablets 120mg [LEO] | res72: Antihypertensives | CPRD_product_code | drug |
1904 | enalapril tablets 20mg | res72: Antihypertensives | CPRD_product_code | drug |
19055 | chlortalidone with atenolol tablets 12.5mg+50mg | res72: Antihypertensives | CPRD_product_code | drug |
19056 | FUROSEMIDE solution sugar-free 50mg/5ml [ROSEMONT] | res72: Antihypertensives | CPRD_product_code | drug |
19129 | SYSCOR MR modified release tablet 10mg [FOREST] | res72: Antihypertensives | CPRD_product_code | drug |
19142 | bendroflumethiazide with timolol maleate tablets 2.5mg + 10mg | res72: Antihypertensives | CPRD_product_code | drug |
19170 | TENSIPINE MR tablets 10mg [GENUS] | res72: Antihypertensives | CPRD_product_code | drug |
19172 | ATENOLOL tablets 25mg [IVAX] | res72: Antihypertensives | CPRD_product_code | drug |
19178 | BISOPROLOL tablets 10mg [RANBAXY] | res72: Antihypertensives | CPRD_product_code | drug |
19182 | ATENOLOL tablets 50mg [IVAX] | res72: Antihypertensives | CPRD_product_code | drug |
19191 | ATENOLOL tablets 100mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
19192 | FUROSEMIDE tablets 40mg [M&A PHARM] | res72: Antihypertensives | CPRD_product_code | drug |
19193 | DOXAZOSIN tablets 2mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
19194 | FUROSEMIDE tablets 20mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
19195 | SPIRONOLACTONE tablets 50mg [WYETH PHAR] | res72: Antihypertensives | CPRD_product_code | drug |
19198 | LISINOPRIL tablets 20mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
19200 | BISOPROLOL tablets 5mg [IVAX] | res72: Antihypertensives | CPRD_product_code | drug |
19202 | CARVEDILOL tablets 6.25mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
19204 | LISINOPRIL tablets 5mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
19208 | ENALAPRIL tablets 10mg [ACTAVIS] | res72: Antihypertensives | CPRD_product_code | drug |
19216 | DOXAZOSIN tablets 4mg [IVAX] | res72: Antihypertensives | CPRD_product_code | drug |
19223 | LISINOPRIL tablets 10mg [TEVA] | res72: Antihypertensives | CPRD_product_code | drug |
193 | co-amilofruse (amiloride and furosemide) tablets 2.5mg+20mg | res72: Antihypertensives | CPRD_product_code | drug |
19352 | Xuret 0.5mg Tablet (Galen Ltd) | res72: Antihypertensives | CPRD_product_code | drug |
19426 | DISOGRAM SR capsules 240mg [RANBAXY] | res72: Antihypertensives | CPRD_product_code | drug |
19437 | EUCARDIC tablets 25mg [ROCHE] | res72: Antihypertensives | CPRD_product_code | drug |
19440 | DISOGRAM SR capsules 300mg [RANBAXY] | res72: Antihypertensives | CPRD_product_code | drug |
196 | enalapril tablets 5mg | res72: Antihypertensives | CPRD_product_code | drug |
19690 | verapamil hydrochloride with trandolapril modified release capsules 180mg + 2mg | res72: Antihypertensives | CPRD_product_code | drug |
19823 | ALPHAVASE tablets 5mg [ASHBOURNE] | res72: Antihypertensives | CPRD_product_code | drug |
19853 | CARDICOR tablets 3.75mg [MERCK SER] | res72: Antihypertensives | CPRD_product_code | drug |
19858 | CARDICOR tablets 10mg [MERCK SER] | res72: Antihypertensives | CPRD_product_code | drug |
19890 | hydrochlorothiazide with amiloride tablets 25mg+2.5mg | res72: Antihypertensives | CPRD_product_code | drug |
1995 | diltiazem 12 hour modified release capsules 120mg | res72: Antihypertensives | CPRD_product_code | drug |
2 | bendroflumethiazide tablets 2.5mg | res72: Antihypertensives | CPRD_product_code | drug |
2001 | ALDACTIDE film coated tablets 25mg + 25mg [PHARMACIA] | res72: Antihypertensives | CPRD_product_code | drug |
20012 | VISKEN tablets 15mg [SOVEREIGN] | res72: Antihypertensives | CPRD_product_code | drug |
2002 | amiloride hydrochloride with hydrochlorothiazide tablets 5mg + 50mg |