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Diabetes

Alison K Wright, Evangelos Kontopantelis, Richard Emsley, Ian Buchan, Mamas A Mamas, Naveed Sattar, Darren M Ashcroft, Martin M Rutter

Type
Disease or Syndrome
ID
PH921
Version ID
1921
Data Sources
Valid event data range
01/01/2006 - 31/12/2013
Sex
Female, Male
Agreement Date
2019-06-11
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

BACKGROUND:

With recent changes in the United Kingdom’s clinical practice for diabetes mellitus care, contemporary estimates of sex disparities in cardiovascular risk and risk factor management are needed.

METHODS:

In this retrospective cohort study, using the Clinical Practice Research Datalink linked to hospital and death records for people in England, we identified 79 985 patients with incident type 2 diabetes mellitus (T2DM) between 2006 to 2013 matched to 386 547 patients without diabetes mellitus. Sex-stratified Cox models were used to assess cardiovascular risk.

RESULTS:

Compared with women without T2DM, women with T2DM had a higher cardiovascular event risk (adjusted hazard ratio, 1.20 [95% confidence interval, 1.12–1.28]) with similar corresponding data in men (hazard ratio, 1.12 [1.06–1.19]), leading to a nonsignificant higher relative risk in women (risk ratio, 1.07 [0.98–1.17]). However, some important sex differences in the management of risk factors were observed. Compared with men with T2DM, women with T2DM were more likely to be obese, hypertensive, and have hypercholesterolemia, but were less likely to be prescribed lipid-lowering medication and angiotensin-converting enzyme inhibitors, especially if they had cardiovascular disease.

CONCLUSIONS:

Compared with men developing T2DM, women with T2DM do not have a significantly higher relative increase in cardiovascular risk, but ongoing sex disparities in prescribing should prompt heightened efforts to improve the standard and equity of diabetes mellitus care in women and men.

Publications

  • Alison K Wright,Evangelos Kontopantelis, Richard Emsley, Ian Buchan, Mamas A Mamas, Naveed Sattar, Darren M Ashcroft, Martin K Rutter, , Cardiovascular Risk and Risk Factor Management in Type 2 Diabetes Mellitus A Population-Based Cohort Study Assessing Sex Disparities. Circulation, 139:2742-2753, 2019.

Clinical Code List

Rows: 208
Code Description Entity type Category Coding System (Read)
C100011 Insulin dependent diabetes mellitus res72: Diabetes diagnostic Read
C100112 Non-insulin dependent diabetes mellitus res72: Diabetes diagnostic Read
C103y00 Other specified diabetes mellitus with coma res72: Diabetes diagnostic Read
C108.00 Insulin dependent diabetes mellitus res72: Diabetes diagnostic Read
C108.11 IDDM-Insulin dependent diabetes mellitus res72: Diabetes diagnostic Read
C108.12 Type 1 diabetes mellitus res72: Diabetes diagnostic Read
C108.13 Type I diabetes mellitus res72: Diabetes diagnostic Read
C108000 Insulin-dependent diabetes mellitus with renal complications res72: Diabetes diagnostic Read
C108011 Type I diabetes mellitus with renal complications res72: Diabetes diagnostic Read
C108012 Type 1 diabetes mellitus with renal complications res72: Diabetes diagnostic Read
C108100 Insulin-dependent diabetes mellitus with ophthalmic comps res72: Diabetes diagnostic Read
C108112 Type 1 diabetes mellitus with ophthalmic complications res72: Diabetes diagnostic Read
C108200 Insulin-dependent diabetes mellitus with neurological comps res72: Diabetes diagnostic Read
C108211 Type I diabetes mellitus with neurological complications res72: Diabetes diagnostic Read
C108212 Type 1 diabetes mellitus with neurological complications res72: Diabetes diagnostic Read
C108300 Insulin dependent diabetes mellitus with multiple complicatn res72: Diabetes diagnostic Read
C108311 Type I diabetes mellitus with multiple complications res72: Diabetes diagnostic Read
C108411 Unstable type I diabetes mellitus res72: Diabetes diagnostic Read
C108412 Unstable type 1 diabetes mellitus res72: Diabetes diagnostic Read
C108500 Insulin dependent diabetes mellitus with ulcer res72: Diabetes diagnostic Read
C108511 Type I diabetes mellitus with ulcer res72: Diabetes diagnostic Read
C108512 Type 1 diabetes mellitus with ulcer res72: Diabetes diagnostic Read
C108600 Insulin dependent diabetes mellitus with gangrene res72: Diabetes diagnostic Read
C108700 Insulin dependent diabetes mellitus with retinopathy res72: Diabetes diagnostic Read
C108711 Type I diabetes mellitus with retinopathy res72: Diabetes diagnostic Read
C108712 Type 1 diabetes mellitus with retinopathy res72: Diabetes diagnostic Read
C108800 Insulin dependent diabetes mellitus - poor control res72: Diabetes diagnostic Read
C108811 Type I diabetes mellitus - poor control res72: Diabetes diagnostic Read
C108812 Type 1 diabetes mellitus - poor control res72: Diabetes diagnostic Read
C108911 Type I diabetes mellitus maturity onset res72: Diabetes diagnostic Read
C108A00 Insulin-dependent diabetes without complication res72: Diabetes diagnostic Read
C108A11 Type I diabetes mellitus without complication res72: Diabetes diagnostic Read
C108B00 Insulin dependent diabetes mellitus with mononeuropathy res72: Diabetes diagnostic Read
C108B11 Type I diabetes mellitus with mononeuropathy res72: Diabetes diagnostic Read
C108C00 Insulin dependent diabetes mellitus with polyneuropathy res72: Diabetes diagnostic Read
C108D00 Insulin dependent diabetes mellitus with nephropathy res72: Diabetes diagnostic Read
C108D11 Type I diabetes mellitus with nephropathy res72: Diabetes diagnostic Read
C108E00 Insulin dependent diabetes mellitus with hypoglycaemic coma res72: Diabetes diagnostic Read
C108E11 Type I diabetes mellitus with hypoglycaemic coma res72: Diabetes diagnostic Read
C108E12 Type 1 diabetes mellitus with hypoglycaemic coma res72: Diabetes diagnostic Read
C108F00 Insulin dependent diabetes mellitus with diabetic cataract res72: Diabetes diagnostic Read
C108F11 Type I diabetes mellitus with diabetic cataract res72: Diabetes diagnostic Read
C108F12 Type 1 diabetes mellitus with diabetic cataract res72: Diabetes diagnostic Read
C108G00 Insulin dependent diab mell with peripheral angiopathy res72: Diabetes diagnostic Read
C108H00 Insulin dependent diabetes mellitus with arthropathy res72: Diabetes diagnostic Read
C108H11 Type I diabetes mellitus with arthropathy res72: Diabetes diagnostic Read
C108J00 Insulin dependent diab mell with neuropathic arthropathy res72: Diabetes diagnostic Read
C108J11 Type I diabetes mellitus with neuropathic arthropathy res72: Diabetes diagnostic Read
C108J12 Type 1 diabetes mellitus with neuropathic arthropathy res72: Diabetes diagnostic Read
C109.00 Non-insulin dependent diabetes mellitus res72: Diabetes diagnostic Read
C109.11 NIDDM - Non-insulin dependent diabetes mellitus res72: Diabetes diagnostic Read
C109.12 Type 2 diabetes mellitus res72: Diabetes diagnostic Read
C109.13 Type II diabetes mellitus res72: Diabetes diagnostic Read
C109000 Non-insulin-dependent diabetes mellitus with renal comps res72: Diabetes diagnostic Read
C109011 Type II diabetes mellitus with renal complications res72: Diabetes diagnostic Read
C109012 Type 2 diabetes mellitus with renal complications res72: Diabetes diagnostic Read
C109100 Non-insulin-dependent diabetes mellitus with ophthalm comps res72: Diabetes diagnostic Read
C109111 Type II diabetes mellitus with ophthalmic complications res72: Diabetes diagnostic Read
C109112 Type 2 diabetes mellitus with ophthalmic complications res72: Diabetes diagnostic Read
C109200 Non-insulin-dependent diabetes mellitus with neuro comps res72: Diabetes diagnostic Read
C109211 Type II diabetes mellitus with neurological complications res72: Diabetes diagnostic Read
C109212 Type 2 diabetes mellitus with neurological complications res72: Diabetes diagnostic Read
C109300 Non-insulin-dependent diabetes mellitus with multiple comps res72: Diabetes diagnostic Read
C109312 Type 2 diabetes mellitus with multiple complications res72: Diabetes diagnostic Read
C109400 Non-insulin dependent diabetes mellitus with ulcer res72: Diabetes diagnostic Read
C109411 Type II diabetes mellitus with ulcer res72: Diabetes diagnostic Read
C109412 Type 2 diabetes mellitus with ulcer res72: Diabetes diagnostic Read
C109500 Non-insulin dependent diabetes mellitus with gangrene res72: Diabetes diagnostic Read
C109511 Type II diabetes mellitus with gangrene res72: Diabetes diagnostic Read
C109512 Type 2 diabetes mellitus with gangrene res72: Diabetes diagnostic Read
C109600 Non-insulin-dependent diabetes mellitus with retinopathy res72: Diabetes diagnostic Read
C109611 Type II diabetes mellitus with retinopathy res72: Diabetes diagnostic Read
C109612 Type 2 diabetes mellitus with retinopathy res72: Diabetes diagnostic Read
C109700 Non-insulin dependent diabetes mellitus - poor control res72: Diabetes diagnostic Read
C109711 Type II diabetes mellitus - poor control res72: Diabetes diagnostic Read
C109712 Type 2 diabetes mellitus - poor control res72: Diabetes diagnostic Read
C109900 Non-insulin-dependent diabetes mellitus without complication res72: Diabetes diagnostic Read
C109911 Type II diabetes mellitus without complication res72: Diabetes diagnostic Read
C109912 Type 2 diabetes mellitus without complication res72: Diabetes diagnostic Read
C109A00 Non-insulin dependent diabetes mellitus with mononeuropathy res72: Diabetes diagnostic Read
C109A11 Type II diabetes mellitus with mononeuropathy res72: Diabetes diagnostic Read
C109B00 Non-insulin dependent diabetes mellitus with polyneuropathy res72: Diabetes diagnostic Read
C109B11 Type II diabetes mellitus with polyneuropathy res72: Diabetes diagnostic Read
C109B12 Type 2 diabetes mellitus with polyneuropathy res72: Diabetes diagnostic Read
C109C00 Non-insulin dependent diabetes mellitus with nephropathy res72: Diabetes diagnostic Read
C109C11 Type II diabetes mellitus with nephropathy res72: Diabetes diagnostic Read
C109C12 Type 2 diabetes mellitus with nephropathy res72: Diabetes diagnostic Read
C109D00 Non-insulin dependent diabetes mellitus with hypoglyca coma res72: Diabetes diagnostic Read
C109D11 Type II diabetes mellitus with hypoglycaemic coma res72: Diabetes diagnostic Read
C109D12 Type 2 diabetes mellitus with hypoglycaemic coma res72: Diabetes diagnostic Read
C109E00 Non-insulin depend diabetes mellitus with diabetic cataract res72: Diabetes diagnostic Read
C109E11 Type II diabetes mellitus with diabetic cataract res72: Diabetes diagnostic Read
C109E12 Type 2 diabetes mellitus with diabetic cataract res72: Diabetes diagnostic Read
C109F11 Type II diabetes mellitus with peripheral angiopathy res72: Diabetes diagnostic Read
C109F12 Type 2 diabetes mellitus with peripheral angiopathy res72: Diabetes diagnostic Read
C109G00 Non-insulin dependent diabetes mellitus with arthropathy res72: Diabetes diagnostic Read
C109G11 Type II diabetes mellitus with arthropathy res72: Diabetes diagnostic Read
C109G12 Type 2 diabetes mellitus with arthropathy res72: Diabetes diagnostic Read
C109H11 Type II diabetes mellitus with neuropathic arthropathy res72: Diabetes diagnostic Read
C109H12 Type 2 diabetes mellitus with neuropathic arthropathy res72: Diabetes diagnostic Read
C109J00 Insulin treated Type 2 diabetes mellitus res72: Diabetes diagnostic Read
C109J11 Insulin treated non-insulin dependent diabetes mellitus res72: Diabetes diagnostic Read
C109J12 Insulin treated Type II diabetes mellitus res72: Diabetes diagnostic Read
C109K00 Hyperosmolar non-ketotic state in type 2 diabetes mellitus res72: Diabetes diagnostic Read
C10E.00 Type 1 diabetes mellitus res72: Diabetes diagnostic Read
C10E.11 Type I diabetes mellitus res72: Diabetes diagnostic Read
C10E.12 Insulin dependent diabetes mellitus res72: Diabetes diagnostic Read
C10E000 Type 1 diabetes mellitus with renal complications res72: Diabetes diagnostic Read
C10E011 Type I diabetes mellitus with renal complications res72: Diabetes diagnostic Read
C10E012 Insulin-dependent diabetes mellitus with renal complications res72: Diabetes diagnostic Read
C10E100 Type 1 diabetes mellitus with ophthalmic complications res72: Diabetes diagnostic Read
C10E111 Type I diabetes mellitus with ophthalmic complications res72: Diabetes diagnostic Read
C10E112 Insulin-dependent diabetes mellitus with ophthalmic comps res72: Diabetes diagnostic Read
C10E200 Type 1 diabetes mellitus with neurological complications res72: Diabetes diagnostic Read
C10E212 Insulin-dependent diabetes mellitus with neurological comps res72: Diabetes diagnostic Read
C10E300 Type 1 diabetes mellitus with multiple complications res72: Diabetes diagnostic Read
C10E311 Type I diabetes mellitus with multiple complications res72: Diabetes diagnostic Read
C10E312 Insulin dependent diabetes mellitus with multiple complicat res72: Diabetes diagnostic Read
C10E400 Unstable type 1 diabetes mellitus res72: Diabetes diagnostic Read
C10E411 Unstable type I diabetes mellitus res72: Diabetes diagnostic Read
C10E412 Unstable insulin dependent diabetes mellitus res72: Diabetes diagnostic Read
C10E500 Type 1 diabetes mellitus with ulcer res72: Diabetes diagnostic Read
C10E511 Type I diabetes mellitus with ulcer res72: Diabetes diagnostic Read
C10E512 Insulin dependent diabetes mellitus with ulcer res72: Diabetes diagnostic Read
C10E600 Type 1 diabetes mellitus with gangrene res72: Diabetes diagnostic Read
C10E611 Type I diabetes mellitus with gangrene res72: Diabetes diagnostic Read
C10E612 Insulin dependent diabetes mellitus with gangrene res72: Diabetes diagnostic Read
C10E700 Type 1 diabetes mellitus with retinopathy res72: Diabetes diagnostic Read
C10E711 Type I diabetes mellitus with retinopathy res72: Diabetes diagnostic Read
C10E712 Insulin dependent diabetes mellitus with retinopathy res72: Diabetes diagnostic Read
C10E800 Type 1 diabetes mellitus - poor control res72: Diabetes diagnostic Read
C10E811 Type I diabetes mellitus - poor control res72: Diabetes diagnostic Read
C10E812 Insulin dependent diabetes mellitus - poor control res72: Diabetes diagnostic Read
C10EA00 Type 1 diabetes mellitus without complication res72: Diabetes diagnostic Read
C10EA11 Type I diabetes mellitus without complication res72: Diabetes diagnostic Read
C10EA12 Insulin-dependent diabetes without complication res72: Diabetes diagnostic Read
C10EB00 Type 1 diabetes mellitus with mononeuropathy res72: Diabetes diagnostic Read
C10EC00 Type 1 diabetes mellitus with polyneuropathy res72: Diabetes diagnostic Read
C10EC11 Type I diabetes mellitus with polyneuropathy res72: Diabetes diagnostic Read
C10EC12 Insulin dependent diabetes mellitus with polyneuropathy res72: Diabetes diagnostic Read
C10ED00 Type 1 diabetes mellitus with nephropathy res72: Diabetes diagnostic Read
C10ED12 Insulin dependent diabetes mellitus with nephropathy res72: Diabetes diagnostic Read
C10EE00 Type 1 diabetes mellitus with hypoglycaemic coma res72: Diabetes diagnostic Read
C10EE12 Insulin dependent diabetes mellitus with hypoglycaemic coma res72: Diabetes diagnostic Read
C10EF00 Type 1 diabetes mellitus with diabetic cataract res72: Diabetes diagnostic Read
C10EF12 Insulin dependent diabetes mellitus with diabetic cataract res72: Diabetes diagnostic Read
C10EG00 Type 1 diabetes mellitus with peripheral angiopathy res72: Diabetes diagnostic Read
C10EH00 Type 1 diabetes mellitus with arthropathy res72: Diabetes diagnostic Read
C10EJ00 Type 1 diabetes mellitus with neuropathic arthropathy res72: Diabetes diagnostic Read
C10EK00 Type 1 diabetes mellitus with persistent proteinuria res72: Diabetes diagnostic Read
C10EL00 Type 1 diabetes mellitus with persistent microalbuminuria res72: Diabetes diagnostic Read
C10EL11 Type I diabetes mellitus with persistent microalbuminuria res72: Diabetes diagnostic Read
C10EM00 Type 1 diabetes mellitus with ketoacidosis res72: Diabetes diagnostic Read
C10EM11 Type I diabetes mellitus with ketoacidosis res72: Diabetes diagnostic Read
C10EN00 Type 1 diabetes mellitus with ketoacidotic coma res72: Diabetes diagnostic Read
C10EN11 Type I diabetes mellitus with ketoacidotic coma res72: Diabetes diagnostic Read
C10EP00 Type 1 diabetes mellitus with exudative maculopathy res72: Diabetes diagnostic Read
C10EP11 Type I diabetes mellitus with exudative maculopathy res72: Diabetes diagnostic Read
C10EQ00 Type 1 diabetes mellitus with gastroparesis res72: Diabetes diagnostic Read
C10EQ11 Type I diabetes mellitus with gastroparesis res72: Diabetes diagnostic Read
C10F.00 Type 2 diabetes mellitus res72: Diabetes diagnostic Read
C10F.11 Type II diabetes mellitus res72: Diabetes diagnostic Read
C10F000 Type 2 diabetes mellitus with renal complications res72: Diabetes diagnostic Read
C10F011 Type II diabetes mellitus with renal complications res72: Diabetes diagnostic Read
C10F100 Type 2 diabetes mellitus with ophthalmic complications res72: Diabetes diagnostic Read
C10F111 Type II diabetes mellitus with ophthalmic complications res72: Diabetes diagnostic Read
C10F200 Type 2 diabetes mellitus with neurological complications res72: Diabetes diagnostic Read
C10F211 Type II diabetes mellitus with neurological complications res72: Diabetes diagnostic Read
C10F300 Type 2 diabetes mellitus with multiple complications res72: Diabetes diagnostic Read
C10F311 Type II diabetes mellitus with multiple complications res72: Diabetes diagnostic Read
C10F400 Type 2 diabetes mellitus with ulcer res72: Diabetes diagnostic Read
C10F411 Type II diabetes mellitus with ulcer res72: Diabetes diagnostic Read
C10F500 Type 2 diabetes mellitus with gangrene res72: Diabetes diagnostic Read
C10F511 Type II diabetes mellitus with gangrene res72: Diabetes diagnostic Read
C10F600 Type 2 diabetes mellitus with retinopathy res72: Diabetes diagnostic Read
C10F611 Type II diabetes mellitus with retinopathy res72: Diabetes diagnostic Read
C10F700 Type 2 diabetes mellitus - poor control res72: Diabetes diagnostic Read
C10F711 Type II diabetes mellitus - poor control res72: Diabetes diagnostic Read
C10F900 Type 2 diabetes mellitus without complication res72: Diabetes diagnostic Read
C10F911 Type II diabetes mellitus without complication res72: Diabetes diagnostic Read
C10FA00 Type 2 diabetes mellitus with mononeuropathy res72: Diabetes diagnostic Read
C10FA11 Type II diabetes mellitus with mononeuropathy res72: Diabetes diagnostic Read
C10FB00 Type 2 diabetes mellitus with polyneuropathy res72: Diabetes diagnostic Read
C10FB11 Type II diabetes mellitus with polyneuropathy res72: Diabetes diagnostic Read
C10FC00 Type 2 diabetes mellitus with nephropathy res72: Diabetes diagnostic Read
C10FC11 Type II diabetes mellitus with nephropathy res72: Diabetes diagnostic Read
C10FD00 Type 2 diabetes mellitus with hypoglycaemic coma res72: Diabetes diagnostic Read
C10FD11 Type II diabetes mellitus with hypoglycaemic coma res72: Diabetes diagnostic Read
C10FE00 Type 2 diabetes mellitus with diabetic cataract res72: Diabetes diagnostic Read
C10FE11 Type II diabetes mellitus with diabetic cataract res72: Diabetes diagnostic Read
C10FF00 Type 2 diabetes mellitus with peripheral angiopathy res72: Diabetes diagnostic Read
C10FF11 Type II diabetes mellitus with peripheral angiopathy res72: Diabetes diagnostic Read
C10FG11 Type II diabetes mellitus with arthropathy res72: Diabetes diagnostic Read
C10FH00 Type 2 diabetes mellitus with neuropathic arthropathy res72: Diabetes diagnostic Read
C10FH11 Type II diabetes mellitus with neuropathic arthropathy res72: Diabetes diagnostic Read
C10FJ00 Insulin treated Type 2 diabetes mellitus res72: Diabetes diagnostic Read
C10FJ11 Insulin treated Type II diabetes mellitus res72: Diabetes diagnostic Read
C10FK00 Hyperosmolar non-ketotic state in type 2 diabetes mellitus res72: Diabetes diagnostic Read
C10FK11 Hyperosmolar non-ketotic state in type II diabetes mellitus res72: Diabetes diagnostic Read
C10FL00 Type 2 diabetes mellitus with persistent proteinuria res72: Diabetes diagnostic Read
C10FL11 Type II diabetes mellitus with persistent proteinuria res72: Diabetes diagnostic Read
C10FM00 Type 2 diabetes mellitus with persistent microalbuminuria res72: Diabetes diagnostic Read
C10FM11 Type II diabetes mellitus with persistent microalbuminuria res72: Diabetes diagnostic Read
C10FN00 Type 2 diabetes mellitus with ketoacidosis res72: Diabetes diagnostic Read
C10FN11 Type II diabetes mellitus with ketoacidosis res72: Diabetes diagnostic Read
C10FP00 Type 2 diabetes mellitus with ketoacidotic coma res72: Diabetes diagnostic Read
C10FQ00 Type 2 diabetes mellitus with exudative maculopathy res72: Diabetes diagnostic Read
C10FR00 Type 2 diabetes mellitus with gastroparesis res72: Diabetes diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH921/version/1921/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH921/version/1921/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH921', '1921', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH921/version/1921/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH921/version/1921/export/codes/?format=json
CSV site_root/phenotypes/PH921/version/1921/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH921', '1921', api_client=client)

Version History

Version
ID
Name Owner Publish date
1921 Diabetes ieuan.scanlon 2022-04-04 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

Print - Print page.