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Agranulocytosis

Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A

Type
Disease or Syndrome
ID
PH93
Version ID
186
Valid event data range
01/01/1999 - 01/07/2016
Sex
Female, Male
Agreement Date
2019-05-20
Coding system
Read codes v2 ICD10 codes Med codes
Tags /Collections
CALIBER Phenotype Library

Definition

At the specified date, a patient is defined as having had 'Agranulocytosis' IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:

Primary care

  1. 'Agranulocytosis' diagnosis or history of diagnosis during a consultation

OR Secondary care (ICD10)

  1. ALL diagnoses of 'Agranulocytosis' or history of diagnosis during a hospitalization

Implementation


Publications

  • Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3

Clinical Code List

Rows: 22
Code Description Disease Medcode Category
42H2.00 Leucopenia - low white count Agranulocytosis 26325.0 Diagnosis of Agranulocytosis
42H2.11 Leucopenia Agranulocytosis 1955.0 Diagnosis of Agranulocytosis
42H4.00 Agranulocytosis Agranulocytosis 21258.0 Diagnosis of Agranulocytosis
42J2.00 Neutropenia Agranulocytosis 4463.0 Diagnosis of Agranulocytosis
D400.00 Agranulocytosis Agranulocytosis 4818.0 Diagnosis of Agranulocytosis
D400.11 Kostmann's syndrome Agranulocytosis 70337.0 Diagnosis of Agranulocytosis
D400.12 Neutropenia Agranulocytosis 2071.0 Diagnosis of Agranulocytosis
D400000 Idiopathic agranulocytosis Agranulocytosis 63204.0 Diagnosis of Agranulocytosis
D400011 Idiopathic neutropenia Agranulocytosis 18054.0 Diagnosis of Agranulocytosis
D400100 Primary splenic neutropenia Agranulocytosis 96380.0 Diagnosis of Agranulocytosis
D400200 Agranulocytosis - drug induced Agranulocytosis 54000.0 Diagnosis of Agranulocytosis
D400211 Neutropenia - drug induced Agranulocytosis 35719.0 Diagnosis of Agranulocytosis
D400312 Neutropenia due to irradiation Agranulocytosis 40310.0 Diagnosis of Agranulocytosis
D400400 Agranulocytosis due to infection Agranulocytosis 50375.0 Diagnosis of Agranulocytosis
D400411 Neutropenia due to infection Agranulocytosis 17705.0 Diagnosis of Agranulocytosis
D400600 Drug-induced neutropenia Agranulocytosis 30008.0 Diagnosis of Agranulocytosis
D400800 Acquired neutropenia NEC Agranulocytosis 49346.0 Diagnosis of Agranulocytosis
D400811 Acquired agranulocytosis NEC Agranulocytosis 65903.0 Diagnosis of Agranulocytosis
D400900 Cyclical neutropenia Agranulocytosis 32141.0 Diagnosis of Agranulocytosis
D400A00 Leucopenia Agranulocytosis 3372.0 Diagnosis of Agranulocytosis
D400y00 Other specified agranulocytosis Agranulocytosis 64300.0 Diagnosis of Agranulocytosis
D400z00 Agranulocytosis NOS Agranulocytosis 63055.0 Diagnosis of Agranulocytosis
Rows: 22
Code Description Disease ReadcodeDescr Readcode
17705.0 Diagnosis of Agranulocytosis Agranulocytosis Neutropenia due to infection D400411
18054.0 Diagnosis of Agranulocytosis Agranulocytosis Idiopathic neutropenia D400011
1955.0 Diagnosis of Agranulocytosis Agranulocytosis Leucopenia 42H2.11
2071.0 Diagnosis of Agranulocytosis Agranulocytosis Neutropenia D400.12
21258.0 Diagnosis of Agranulocytosis Agranulocytosis Agranulocytosis 42H4.00
26325.0 Diagnosis of Agranulocytosis Agranulocytosis Leucopenia - low white count 42H2.00
30008.0 Diagnosis of Agranulocytosis Agranulocytosis Drug-induced neutropenia D400600
32141.0 Diagnosis of Agranulocytosis Agranulocytosis Cyclical neutropenia D400900
3372.0 Diagnosis of Agranulocytosis Agranulocytosis Leucopenia D400A00
35719.0 Diagnosis of Agranulocytosis Agranulocytosis Neutropenia - drug induced D400211
40310.0 Diagnosis of Agranulocytosis Agranulocytosis Neutropenia due to irradiation D400312
4463.0 Diagnosis of Agranulocytosis Agranulocytosis Neutropenia 42J2.00
4818.0 Diagnosis of Agranulocytosis Agranulocytosis Agranulocytosis D400.00
49346.0 Diagnosis of Agranulocytosis Agranulocytosis Acquired neutropenia NEC D400800
50375.0 Diagnosis of Agranulocytosis Agranulocytosis Agranulocytosis due to infection D400400
54000.0 Diagnosis of Agranulocytosis Agranulocytosis Agranulocytosis - drug induced D400200
63055.0 Diagnosis of Agranulocytosis Agranulocytosis Agranulocytosis NOS D400z00
63204.0 Diagnosis of Agranulocytosis Agranulocytosis Idiopathic agranulocytosis D400000
64300.0 Diagnosis of Agranulocytosis Agranulocytosis Other specified agranulocytosis D400y00
65903.0 Diagnosis of Agranulocytosis Agranulocytosis Acquired agranulocytosis NEC D400811
70337.0 Diagnosis of Agranulocytosis Agranulocytosis Kostmann's syndrome D400.11
96380.0 Diagnosis of Agranulocytosis Agranulocytosis Primary splenic neutropenia D400100
Rows: 1
Code Description Disease Category
D70 Agranulocytosis Agranulocytosis Diagnosis of Agranulocytosis

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH93/version/186/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH93/version/186/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH93', '186', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH93/version/186/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH93/version/186/export/codes/?format=json
CSV site_root/phenotypes/PH93/version/186/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH93', '186', api_client=client)

Version History

Version
ID
Name Owner Publish date
186 Agranulocytosis ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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