BACKGROUND:
With recent changes in the United Kingdom’s clinical practice for diabetes mellitus care, contemporary estimates of sex disparities in cardiovascular risk and risk factor management are needed.
METHODS:
In this retrospective cohort study, using the Clinical Practice Research Datalink linked to hospital and death records for people in England, we identified 79 985 patients with incident type 2 diabetes mellitus (T2DM) between 2006 to 2013 matched to 386 547 patients without diabetes mellitus. Sex-stratified Cox models were used to assess cardiovascular risk.
RESULTS:
Compared with women without T2DM, women with T2DM had a higher cardiovascular event risk (adjusted hazard ratio, 1.20 [95% confidence interval, 1.12–1.28]) with similar corresponding data in men (hazard ratio, 1.12 [1.06–1.19]), leading to a nonsignificant higher relative risk in women (risk ratio, 1.07 [0.98–1.17]). However, some important sex differences in the management of risk factors were observed. Compared with men with T2DM, women with T2DM were more likely to be obese, hypertensive, and have hypercholesterolemia, but were less likely to be prescribed lipid-lowering medication and angiotensin-converting enzyme inhibitors, especially if they had cardiovascular disease.
CONCLUSIONS:
Compared with men developing T2DM, women with T2DM do not have a significantly higher relative increase in cardiovascular risk, but ongoing sex disparities in prescribing should prompt heightened efforts to improve the standard and equity of diabetes mellitus care in women and men.
Alison K Wright,Evangelos Kontopantelis, Richard Emsley, Ian Buchan, Mamas A Mamas, Naveed Sattar, Darren M Ashcroft, Martin K Rutter, , Cardiovascular Risk and Risk Factor Management in Type 2 Diabetes Mellitus A Population-Based Cohort Study Assessing Sex Disparities. Circulation, 139:2742-2753, 2019.
Code | Description | Entity type | Category | Coding System (Read) |
---|---|---|---|---|
137..00 | Tobacco consumption | res72: Smoking | diagnostic | Read |
137..11 | Smoker - amount smoked | res72: Smoking | diagnostic | Read |
1371 | Never smoked tobacco | res72: Smoking | diagnostic | Read |
1371.11 | Non-smoker | res72: Smoking | diagnostic | Read |
1372 | Trivial smoker - < 1 cig/day | res72: Smoking | diagnostic | Read |
1372.11 | Occasional smoker | res72: Smoking | diagnostic | Read |
1373 | Light smoker - 1-9 cigs/day | res72: Smoking | diagnostic | Read |
1374 | Moderate smoker - 10-19 cigs/d | res72: Smoking | diagnostic | Read |
1375 | Heavy smoker - 20-39 cigs/day | res72: Smoking | diagnostic | Read |
1376 | Very heavy smoker - 40+cigs/d | res72: Smoking | diagnostic | Read |
1377 | Ex-trivial smoker (<1/day) | res72: Smoking | diagnostic | Read |
1378 | Ex-light smoker (1-9/day) | res72: Smoking | diagnostic | Read |
1379 | Ex-moderate smoker (10-19/day) | res72: Smoking | diagnostic | Read |
137A.00 | Ex-heavy smoker (20-39/day) | res72: Smoking | diagnostic | Read |
137B.00 | Ex-very heavy smoker (40+/day) | res72: Smoking | diagnostic | Read |
137C.00 | Keeps trying to stop smoking | res72: Smoking | diagnostic | Read |
137D.00 | Admitted tobacco cons untrue ? | res72: Smoking | diagnostic | Read |
137E.00 | Tobacco consumption unknown | res72: Smoking | diagnostic | Read |
137F.00 | Ex-smoker - amount unknown | res72: Smoking | diagnostic | Read |
137G.00 | Trying to give up smoking | res72: Smoking | diagnostic | Read |
137H.00 | Pipe smoker | res72: Smoking | diagnostic | Read |
137I.00 | Passive smoker | res72: Smoking | diagnostic | Read |
137J.00 | Cigar smoker | res72: Smoking | diagnostic | Read |
137K.00 | Stopped smoking | res72: Smoking | diagnostic | Read |
137K000 | Recently stopped smoking | res72: Smoking | diagnostic | Read |
137L.00 | Current non-smoker | res72: Smoking | diagnostic | Read |
137M.00 | Rolls own cigarettes | res72: Smoking | diagnostic | Read |
137N.00 | Ex pipe smoker | res72: Smoking | diagnostic | Read |
137O.00 | Ex cigar smoker | res72: Smoking | diagnostic | Read |
137P.00 | Cigarette smoker | res72: Smoking | diagnostic | Read |
137P.11 | Smoker | res72: Smoking | diagnostic | Read |
137Q.00 | Smoking started | res72: Smoking | diagnostic | Read |
137Q.11 | Smoking restarted | res72: Smoking | diagnostic | Read |
137R.00 | Current smoker | res72: Smoking | diagnostic | Read |
137S.00 | Ex smoker | res72: Smoking | diagnostic | Read |
137T.00 | Date ceased smoking | res72: Smoking | diagnostic | Read |
137U.00 | Not a passive smoker | res72: Smoking | diagnostic | Read |
137V.00 | Smoking reduced | res72: Smoking | diagnostic | Read |
137W.00 | Chews tobacco | res72: Smoking | diagnostic | Read |
137X.00 | Cigarette consumption | res72: Smoking | diagnostic | Read |
137Y.00 | Cigar consumption | res72: Smoking | diagnostic | Read |
137Z.00 | Tobacco consumption NOS | res72: Smoking | diagnostic | Read |
137a.00 | Pipe tobacco consumption | res72: Smoking | diagnostic | Read |
137b.00 | Ready to stop smoking | res72: Smoking | diagnostic | Read |
137c.00 | Thinking about stopping smoking | res72: Smoking | diagnostic | Read |
137d.00 | Not interested in stopping smoking | res72: Smoking | diagnostic | Read |
137e.00 | Smoking restarted | res72: Smoking | diagnostic | Read |
137j.00 | Ex-cigarette smoker | res72: Smoking | diagnostic | Read |
137l.00 | Ex roll-up cigarette smoker | res72: Smoking | diagnostic | Read |
137m.00 | Failed attempt to stop smoking | res72: Smoking | diagnostic | Read |
8CAL.00 | Smoking cessation advice | res72: Smoking | diagnostic | Read |
8H7i.00 | Referral to smoking cessation advisor | res72: Smoking | diagnostic | Read |
8HTK.00 | Referral to stop-smoking clinic | res72: Smoking | diagnostic | Read |
8HkQ.00 | Referral to NHS stop smoking service | res72: Smoking | diagnostic | Read |
8IAj.00 | Smoking cessation advice declined | res72: Smoking | diagnostic | Read |
9NS0200 | Referral for smoking cessation service offered | res72: Smoking | diagnostic | Read |
9km..00 | Ex-smoker annual review - enhanced services administration | res72: Smoking | diagnostic | Read |
9km..11 | Ex-smoker annual review | res72: Smoking | diagnostic | Read |
9kn..00 | Non-smoker annual review - enhanced services administration | res72: Smoking | diagnostic | Read |
9kn..11 | Non-smoker annual review | res72: Smoking | diagnostic | Read |
9ko..00 | Current smoker annual review - enhanced services admin | res72: Smoking | diagnostic | Read |
9ko..11 | Current smoker annual review | res72: Smoking | diagnostic | Read |
To Export Phenotype Details:
Format | API |
---|---|
XML | site_root/api/v1/public/phenotypes/PH931/version/1941/detail/?format=xml |
JSON | site_root/api/v1/public/phenotypes/PH931/version/1941/detail/?format=json |
R Package |
|
To Export Phenotype Code List:
Format | API |
---|---|
XML | site_root/api/v1/public/phenotypes/PH931/version/1941/export/codes/?format=xml |
JSON | site_root/api/v1/public/phenotypes/PH931/version/1941/export/codes/?format=json |
CSV | site_root/phenotypes/PH931/version/1941/export/codes/ |
R Package |
|
Version ID |
Name | Owner | Publish date | |
---|---|---|---|---|
1941 | Smoking | ieuan.scanlon | 2022-04-04 | currently shown |
Export - export all codes into a csv file/JSON/XML for the current phenotype version.
Print - Print page.