Bipolar Disorder, Schizophrenia and Other Psychotic Disorders Primary Care

John, A, McGregor, J., Jones, I., Lee, S. C., Walters, J. T. R., Owen, M. J., O'Donovan, M., DelPozo-Banos, M., Berridge, D., & Lloyd, K.

PH940 / 2951 Clinical-Coded Phenotype

  1. Overview

    Phenotype Type
    Disease or syndrome
    Sex
    Both
    Valid Event Date Range
    No data
    Coding System
    Read codes v2
    Data Sources
    GP dataset - Welsh Primary Care
    Collections
    Adolescent Data Platform (ADP)DATAMINDPhenotype Library
    Tags
    No data

  2. Definition

    The attached code lists for bipolar disorder, schizophrenia and other psychotic disorders are based on John et al. (2018) and reviewed by two clinicians (Prof. Keith Lloyd and Prof. Ann John) in the study team. The codes in these lists exclude organic psychoses (e.g., drug and alcohol induced) and psychoses with origins in childhood. In keeping with John et al. (2018), the codes are divided into three categories: 1) schizophrenia-related disorders that include schizophrenia, schizotypal and delusional disorders, 2) bipolar disorder and other mood related disorders that include bipolar disorder, manic depressive episodes with psychotic symptoms, and 3) other psychotic disorders/severe mental illnesses (SMIs). Additional Read codes for 'other psychotic disorders' that were mapped to the ICD-10 codes for acute and transient psychotic disorders (F23), depressive episodes/disorders with psychotic symptoms (F32.3 and F33.3) were added to the list as reviewed by two clinicians (Prof. Keith Lloyd and Prof. Ann John) in the study team. Information on algorithm construction are included in the following papers (Economou et. al. 2012; McGregor et. al. 2010).

  3. Implementation

    Implementation

    No data

  4. Clinical Code List

  5. Publication

    • John, A, McGregor, J., Jones, I., Lee, S. C., Walters, J. T. R., Owen, M. J., O'Donovan, M., DelPozo-Banos, M., Berridge, D., & Lloyd, K. (2018). Premature mortality among people with severe mental illness - New evidence from linked primary care data. Schizophrenia Research, 199, 154-162. https://doi.org/10.1016/j.schres.2018.04.009

      (DOI:10.1016/j.schres.2018.04.009)

    • John, A., Friedmann, Y., Delpozo-Banos, M., Frizzati, A., Ford, T., & Thapar, A. 2022. "Association of School Absence and Exclusion with Recorded Neurodevelopmental Disorders, Mental Disorders, or Self-Harm: A Nationwide, Retrospective, Electronic Cohort Study of Children and Young People in Wales, UK."

    • Economou, A. Michelle G. McGregor, J. Craddock, N. Lyons, R,A. Owen, M.J. Price, V. Thomson, S. Walters, J.T. & Lloyd, K. (2012). "The Health Informatics Cohort Enhancement Project (HICE): Using Routinely Collected Primary Care Data to Identify People with a Lifetime Diagnosis of Psychotic Disorder." BMC Research Notes 5(1):1-6.

    • McGregor, J. Brooks, C. Chalasani, P. Chukwuma, J. Hutchings, H. Lyons, R,A. & Lloyd, K. (2010). "The Health Informatics Trial Enhancement Project (HITE): Using Routinely Collected Primary Care Data to Identify Potential Participants for a Depression Trial." Trials 11(1):1-6.

    • Main reference link: https://www.sciencedirect.com/science/article/pii/S0920996418301981?via%3Dihub

    Citation Example

    John, A, McGregor, J., Jones, I., Lee, S. C., Walters, J. T. R., Owen, M. J., O'Donovan, M., DelPozo-Banos, M., Berridge, D., & Lloyd, K.. PH940 / 2951 - Bipolar Disorder, Schizophrenia and Other Psychotic Disorders Primary Care. Phenotype Library [Online]. 08 November 2023. Available from: http://phenotypes.healthdatagateway.org/phenotypes/PH940/version/2951/detail/. [Accessed 23 November 2024]

  6. API

    To Export Phenotype Details:

    FormatAPI
    JSON site_root/api/v1/phenotypes/PH940/version/2951/detail/?format=json
    R Package

    # Download here

    library(ConceptLibraryClient)


    # Connect to API

    client = ConceptLibraryClient::Connection$new(public=TRUE)


    # Get details of phenotype

    phenotype_details = client$phenotypes$get_detail(
     'PH940',
     version_id=2951
    )

    Py Package

    # Download here

    from pyconceptlibraryclient import Client


    # Connect to API

    client = Client(public=True)


    # Get codelist of phenotype

    phenotype_codelist = client.phenotypes.get_detail(
     'PH940',
     version_id=2951
    )

    To Export Phenotype Code List:

    FormatAPI
    JSON site_root/api/v1/phenotypes/PH940/version/2951/export/codes/?format=json
    CSV site_root/phenotypes/PH940/version/2951/export/codes/
    R Package

    # Download here

    library(ConceptLibraryClient)


    # Connect to API

    client = ConceptLibraryClient::Connection$new(public=TRUE)


    # Get codelist of phenotype

    phenotype_codelist = client$phenotypes$get_codelist(
     'PH940',
     version_id=2951
    )

    Py Package

    # Download here

    from pyconceptlibraryclient import Client


    # Connect to API

    client = Client(public=True)


    # Get codelist of phenotype

    phenotype_codelist = client.phenotypes.get_codelist(
     'PH940',
     version_id=2951
    )

  7. Version History

    Version IDNameOwnerPublish date
    3522 Severe Mental Illnesses ieuan.scanlon2024-07-22
    2966 Severe Mental Illnesses ieuan.scanlon2023-11-13
    2962 Severe Mental Illnesses ieuan.scanlon2023-11-13
    2951 Bipolar Disorder, Schizophrenia and Other Psychotic Disorders Primary Care ieuan.scanlon2023-11-08currently shown
    1959 Bipolar Disorder, Schizophrenia and Other Psychotic Disorders Primary Care ieuan.scanlon2022-05-05