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CCU002_02 Thrombocytopenia

CVD-COVID-UK consortium, William N Whiteley, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Venexia Walker, Rachel Denholm, Ashley Akbari, Efosa Omigie, Sam Hollings, Emanuele Di Angelantonio, Spiros Denaxas, Angela Wood, Jonathan A C Sterne, Cathie Sudlow

Type
Disease or Syndrome
ID
PH996
Version ID
2174
Data Sources
GPES Data for Pandemic Planning and Research (COVID-19) , Hospital Episode Statistics Admitted Patient Care , Civil Registration - Deaths , Trusted Research Environments for CVD-COVID-UK / COVID-IMPACT , Secondary Uses Services Payment By Results
Valid event data range
08/12/2020 - 18/03/2021
Sex
Female, Male
Agreement Date
2021-08-23
Coding system
ICD10 codes SNOMED CT codes
Tags /Collections
BHF Data Science Centre Phenotype Library

Definition

Code type is set to 1 for incident events, and 0 for prevalent events.

Publications

  • Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, and thrombocytopenic events: whole population cohort study in 46 million adults in England CVD-COVID-UK consortium, William N Whiteley, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Venexia Walker, Rachel Denholm, Ashley Akbari, Efosa Omigie, Sam Hollings, Emanuele Di Angelantonio, Spiros Denaxas, Angela Wood, Jonathan A C Sterne, Cathie Sudlow medRxiv 2021.08.18.21262222; doi: https://doi.org/10.1

Clinical Code List

Rows: 33
Code Description terminology code_type
111588002 Heparin associated thrombotic thrombocytopenia SNOMEDCT 1.0
128091003 Autoimmune thrombocytopenia SNOMEDCT 1.0
13172003 Autoimmune thrombocytopenic purpura SNOMEDCT 1.0
154826009 Secondary thrombocytopenia SNOMEDCT 1.0
191322006 Thrombocytopenia caused by drugs SNOMEDCT 1.0
191323001 Thrombocytopenia due to extracorporeal circulation of blood SNOMEDCT 1.0
19307009 Drug-induced immune thrombocytopenia SNOMEDCT 1.0
267534000 Primary thrombocytopenia SNOMEDCT 1.0
28505005 Acute idiopathic thrombocytopenic purpura SNOMEDCT 1.0
2897005 Immune thrombocytopenia SNOMEDCT 1.0
302873008 Thrombocytopenic purpura SNOMEDCT 1.0
32273002 Idiopathic thrombocytopenic purpura SNOMEDCT 1.0
33183004 Post infectious thrombocytopenic purpura SNOMEDCT 1.0
36070007 Immunodeficiency with thrombocytopenia AND eczema SNOMEDCT 1.0
371106008 Idiopathic maternal thrombocytopenia SNOMEDCT 1.0
402653004 Thrombocytopenic purpura due to defective platelet production SNOMEDCT 1.0
402654005 Thrombocytopenic purpura due to platelet consumption SNOMEDCT 1.0
417626001 Thrombocytopenic purpura associated with metabolic disorder SNOMEDCT 1.0
438476003 Autoimmune thrombotic thrombocytopenic purpura SNOMEDCT 1.0
438492008 Hereditary thrombocytopenic disorder SNOMEDCT 1.0
439007008 Acquired thrombotic thrombocytopenic purpura SNOMEDCT 1.0
441322009 Drug induced thrombotic thrombocytopenic purpura SNOMEDCT 1.0
441511006 History of immune thrombocytopenia SNOMEDCT 1.0
49341000119108 History of thrombocytopaenia SNOMEDCT 1.0
726769004 HIT (Heparin induced thrombocytopenia) antibody SNOMEDCT 1.0
73397007 Heparin induced thrombocytopaenia SNOMEDCT 1.0
74576004 Acquired thrombocytopenia SNOMEDCT 1.0
78129009 Thrombotic thrombocytopenic purpura SNOMEDCT 1.0
783251006 Hereditary thrombocytopenia with normal platelets SNOMEDCT 1.0
78345002 Thrombocytopenia due to diminished platelet production SNOMEDCT 1.0
82190001 Thrombocytopenia due to defective platelet production SNOMEDCT 1.0
866152006 Thrombocytopenia due to 2019 novel coronavirus SNOMEDCT 1.0
87902006 Thrombocytopenia due to non-immune destruction SNOMEDCT 1.0
Rows: 5
Code Description terminology code_type
D69.3 Idiopathic thrombocytopenic purpura ICD10 1.0
D69.4 Other primary thrombocytopenia ICD10 1.0
D69.5 Secondary thrombocytopenia ICD10 1.0
D69.6 Thrombocytopenia, unspecified ICD10 1.0
M31.1 Thrombotic microangiopathy ICD10 1.0

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH996/version/2174/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH996/version/2174/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH996', '2174', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH996/version/2174/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH996/version/2174/export/codes/?format=json
CSV site_root/phenotypes/PH996/version/2174/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH996', '2174', api_client=client)

Version History

Version
ID
Name Owner Publish date
2174 CCU002_02 Thrombocytopenia ieuan.scanlon 2022-05-17 currently shown
2071 CCU002_02 Thrombocytopenia ieuan.scanlon 2022-05-09

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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