Phenotype Library | phenotype: Hyposplenism

Hyposplenism

Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A

PH190

Version ID

380

Type

Disease or Syndrome

Data Sources

CPRD GOLD , HES Admitted Patient Care data for CPRD GOLD

Valid event data range

01/01/1999 - 01/07/2016

Sex

♀ Female ♂ Male

Agreement Date

2019-05-20

Coding system

Read codes v2 ICD10 codes Med codes

Collections

CALIBER Phenotype Library

Definition

At the specified date, a patient is defined as having had 'Hyposplenism' IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:

Primary care

'Hyposplenism' diagnosis or history of diagnosis or procedure during a consultation

OR Secondary care (ICD10)

ALL diagnoses of 'Hyposplenism' or history of diagnosis during a hospitalization

Implementation

PhenoFlow Implementation:

https://kclhi.org/phenoflow/phenotype/download/547

Publications

Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3

Clinical Code List

CSV

JSON

XML

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C1230/3599 Hyposplenism - Primary care - Read codes v2

Rows: 19

Code	Description	Disease	Medcode	Category
14N7.00	H/O: splenectomy	Hyposplenism	16827.0	History of Hyposplenism
7840.00	Total excision of spleen	Hyposplenism	34310.0	Procedure leading to Hyposplenism
7840.11	Total splenectomy	Hyposplenism	2759.0	Procedure leading to Hyposplenism
7840100.0	Total splenectomy	Hyposplenism	27514.0	Procedure leading to Hyposplenism
7840300.0	Splenectomy NEC	Hyposplenism	1393.0	Procedure leading to Hyposplenism
7840400.0	Laparoscopic total splenectomy	Hyposplenism	31041.0	Procedure leading to Hyposplenism
7840y00	Other specified total excision of spleen	Hyposplenism	102966.0	Procedure leading to Hyposplenism
7840z00	Total excision of spleen NOS	Hyposplenism	59784.0	Procedure leading to Hyposplenism
7841.00	Other excision of spleen	Hyposplenism	48198.0	Procedure leading to Hyposplenism
7841y00	Other specified other excision of spleen	Hyposplenism	102207.0	Procedure leading to Hyposplenism
7841z00	Other excision of spleen NOS	Hyposplenism	64291.0	Procedure leading to Hyposplenism
D415400	Splenic atrophy	Hyposplenism	66973.0	Diagnosis of Hyposplenism
D415600	Splenic fibrosis	Hyposplenism	66980.0	Diagnosis of Hyposplenism
D415700	Splenic infarction	Hyposplenism	9368.0	Diagnosis of Hyposplenism
D415800	Non-traumatic rupture of spleen	Hyposplenism	62557.0	Diagnosis of Hyposplenism
D415A00	Hyposplenism	Hyposplenism	39034.0	Diagnosis of Hyposplenism
PK01.00	Absent spleen	Hyposplenism	22319.0	Diagnosis of Hyposplenism
PK01.11	Asplenia	Hyposplenism	10505.0	Diagnosis of Hyposplenism
PK06.00	Hypoplasia of spleen	Hyposplenism	71462.0	Diagnosis of Hyposplenism

C1231/3601 Hyposplenism - Primary care - Med codes

Rows: 19

Code	Description	Disease	ReadcodeDescr	Readcode
102207.0	Procedure leading to Hyposplenism	Hyposplenism	Other specified other excision of spleen	7841y00
102966.0	Procedure leading to Hyposplenism	Hyposplenism	Other specified total excision of spleen	7840y00
10505.0	Diagnosis of Hyposplenism	Hyposplenism	Asplenia	PK01.11
1393.0	Procedure leading to Hyposplenism	Hyposplenism	Splenectomy NEC	7840300.0
16827.0	History of Hyposplenism	Hyposplenism	H/O: splenectomy	14N7.00
22319.0	Diagnosis of Hyposplenism	Hyposplenism	Absent spleen	PK01.00
27514.0	Procedure leading to Hyposplenism	Hyposplenism	Total splenectomy	7840100.0
2759.0	Procedure leading to Hyposplenism	Hyposplenism	Total splenectomy	7840.11
31041.0	Procedure leading to Hyposplenism	Hyposplenism	Laparoscopic total splenectomy	7840400.0
34310.0	Procedure leading to Hyposplenism	Hyposplenism	Total excision of spleen	7840.00
39034.0	Diagnosis of Hyposplenism	Hyposplenism	Hyposplenism	D415A00
48198.0	Procedure leading to Hyposplenism	Hyposplenism	Other excision of spleen	7841.00
59784.0	Procedure leading to Hyposplenism	Hyposplenism	Total excision of spleen NOS	7840z00
62557.0	Diagnosis of Hyposplenism	Hyposplenism	Non-traumatic rupture of spleen	D415800
64291.0	Procedure leading to Hyposplenism	Hyposplenism	Other excision of spleen NOS	7841z00
66973.0	Diagnosis of Hyposplenism	Hyposplenism	Splenic atrophy	D415400
66980.0	Diagnosis of Hyposplenism	Hyposplenism	Splenic fibrosis	D415600
71462.0	Diagnosis of Hyposplenism	Hyposplenism	Hypoplasia of spleen	PK06.00
9368.0	Diagnosis of Hyposplenism	Hyposplenism	Splenic infarction	D415700

C1232/3603 Hyposplenism - Secondary care - Diagnoses - ICD10 codes

Rows: 2

Code	Description	Disease	Category
D73.0	Hyposplenism	Hyposplenism	Diagnosis of Hyposplenism
D73.5	Infarction of spleen	Hyposplenism	Diagnosis of Hyposplenism

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH190/version/380/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH190/version/380/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH190', '380', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH190/version/380/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH190/version/380/export/codes/?format=json
CSV	site_root/phenotypes/PH190/version/380/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH190', '380', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
380	Hyposplenism	ieuan.scanlon	2021-10-06	currently shown