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Other ADDs

Matthew J Carr, Darren M Ashcroft, Evangelos Kontopantelis, David While, Yvonne Awenat, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb

Type
Drug
ID
PH383
Version ID
766
Data Sources
Valid event data range
01/01/2001 - 31/12/2013
Sex
Female, Male
Agreement Date
2017-05-01
Coding system
Multilex codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

PURPOSE:

Self-harm is a public health problem that requires a better understanding of mortality risk. We undertook a study to examine premature mortality in a nationally representative cohort of primary care patients who had harmed themselves.

METHODS:

During 2001-2013, a total of 385 general practices in England contributed data to the Clinical Practice Research Datalink with linkage to Office for National Statistics mortality records. We identified 30,017 persons aged 15 to 64 years with a recorded episode of self-harm. We estimated the relative risks of all-cause and cause-specific natural and unnatural mortality using a comparison cohort of 600,258 individuals matched on age, sex, and general practice.

RESULTS:

We found an elevated risk of dying prematurely from any cause among the self-harm cohort, especially in the first year of follow-up (adjusted hazard ratio for that year, 3.6; 95% CI, 3.1-4.2). In particular, suicide risk was especially high during the first year (adjusted hazard ratio, 54.4; 95% CI, 34.3-86.3); although it declined sharply, it remained much higher than that in the comparison cohort. Large elevations of risk throughout the follow-up period were also observed for accidental, alcohol-related, and drug poisoning deaths. At 10 years of follow-up, cumulative incidence values were 6.5% (95% CI, 6.0%-7.1%) for allcause mortality and 1.3% (95% CI, 1.2%-1.5%) for suicide.

CONCLUSIONS:

Primary care patients who have harmed themselves are at greatly increased risk of dying prematurely by natural and unnatural causes, and especially within a year of a first episode. These individuals visit clinicians at a relatively high frequency, which presents a clear opportunity for preventive action. Primary care patients with myriad comorbidities, including self-harming behavior, mental disorder, addictions, and physical illnesses, will require concerted, multipronged, multidisciplinary collaborative care approaches.

Publications

  • Matthew J Carr, Darren M Ashcroft, Evangelos Kontopantelis, David While, Yvonne Awenat, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb, Premature Death Among Primary Care Patients With a History of Self-Harm. Annals of Family Medicine, 15(3), 2017.

Clinical Code List

Rows: 128
Code Description Entity type Coding System (Multilex) Category
10967020 Duloxetine 60mg gastro-resistant capsules (Sigma Pharmaceuticals Plc) res41: Other ADDs Multilex drug
21206020 Mirtazapine 15mg/ml oral solution sugar free (A A H Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
35355020 Venlafaxine 150mg/5ml oral solution res41: Other ADDs Multilex drug
35357020 Venlafaxine 37.5mg/5ml oral solution res41: Other ADDs Multilex drug
35359020 Venlafaxine 75mg/5ml oral solution res41: Other ADDs Multilex drug
3818020 Fluanxol 1mg tablets (Sigma Pharmaceuticals Plc) res41: Other ADDs Multilex drug
38595020 Mirtazapine 15mg tablets (Medreich Plc) res41: Other ADDs Multilex drug
3942020 Venlafaxine 37.5mg tablets (Ranbaxy (UK) Ltd) res41: Other ADDs Multilex drug
3965020 Venlablue XL 75mg capsules (Bluefish Pharmaceuticals AB) res41: Other ADDs Multilex drug
3966020 Alventa XL 75mg capsules (Consilient Health Ltd) res41: Other ADDs Multilex drug
3970020 Efexor XL 150mg capsules (Waymade Healthcare Plc) res41: Other ADDs Multilex drug
3976020 Venlablue XL 150mg capsules (Bluefish Pharmaceuticals AB) res41: Other ADDs Multilex drug
3977020 Alventa XL 150mg capsules (Consilient Health Ltd) res41: Other ADDs Multilex drug
41252020 Mirtazapine 15mg orodispersible tablets sugar free res41: Other ADDs Multilex drug
41253020 Mirtazapine 15mg orodispersible tablets sugar free (Sandoz Ltd) res41: Other ADDs Multilex drug
41254020 Mirtazapine 45mg orodispersible tablets sugar free res41: Other ADDs Multilex drug
48376020 Efexor 37.5mg tablets (Wyeth Pharmaceuticals) res41: Other ADDs Multilex drug
48377020 Efexor 75mg tablets (Wyeth Pharmaceuticals) res41: Other ADDs Multilex drug
49502020 Fluanxol 500microgram tablets (Lundbeck Ltd) res41: Other ADDs Multilex drug
49503020 Fluanxol 1mg tablets (Lundbeck Ltd) res41: Other ADDs Multilex drug
50286020 Marplan 10mg Tablet (Cambridge Laboratories Ltd) res41: Other ADDs Multilex drug
50620020 Nardil 15mg tablets (Archimedes Pharma UK Ltd) res41: Other ADDs Multilex drug
50868020 Optimax 500mg tablets (Merck Serono Ltd) res41: Other ADDs Multilex drug
50957020 Pacitron 500mg Tablet (Rorer Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
51010020 Parnate 10mg Tablet (Goldshield Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
51013020 Parstelin Tablet (GlaxoSmithKline Consumer Healthcare) res41: Other ADDs Multilex drug
54686020 Venlafaxine 37.5mg tablets res41: Other ADDs Multilex drug
54687020 Venlafaxine 75mg tablets res41: Other ADDs Multilex drug
54978020 Optimax wv Tablet (E. Merck) res41: Other ADDs Multilex drug
59180020 Isocarboxazid 10mg Tablet (Cambridge Laboratories Ltd) res41: Other ADDs Multilex drug
62025020 Flupentixol 500microgram tablets res41: Other ADDs Multilex drug
62026020 Flupentixol 1mg tablets res41: Other ADDs Multilex drug
63638020 Isocarboxazid 10mg tablets res41: Other ADDs Multilex drug
63795020 Moclobemide 150mg tablets (Teva UK Ltd) res41: Other ADDs Multilex drug
65266020 Tranylcypromine 10mg tablets (AMCo) res41: Other ADDs Multilex drug
65635020 Phenelzine 15mg tablets res41: Other ADDs Multilex drug
67145020 Tranylcypromine 10mg tablets res41: Other ADDs Multilex drug
67148020 Tranylcypromine with trifluoperazine Tablet res41: Other ADDs Multilex drug
67310020 Tryptophan 500mg tablets res41: Other ADDs Multilex drug
67314020 Tryptophan with ascorbic acid and pyridoxine powder res41: Other ADDs Multilex drug
68128020 Mirtazapine 15mg/ml oral solution sugar free (Rosemont Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
68213020 Mirtazapine 30mg tablets (Actavis UK Ltd) res41: Other ADDs Multilex drug
68484020 Mirtazapine 30mg tablets (A A H Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
69003020 Trifluoperazine with tranylcypromine 1mg + 10mg Tablet res41: Other ADDs Multilex drug
69827020 Mirtazapine 15mg tablets (A A H Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
69832020 Mirtazapine 45mg tablets (A A H Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
70353020 Mirtazapine 15mg tablets (Arrow Generics Ltd) res41: Other ADDs Multilex drug
71074020 Mirtazapine 15mg tablets (Genus Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
71994020 Manerix 150mg tablets (Meda Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
71995020 Manerix 300mg tablets (Meda Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
72031020 Moclobemide 150mg tablets res41: Other ADDs Multilex drug
72032020 Moclobemide 300mg tablets res41: Other ADDs Multilex drug
74026020 Mirtazapine 15mg orodispersible tablets (Teva UK Ltd) res41: Other ADDs Multilex drug
74033020 Mirtazapine 45mg orodispersible tablets (Teva UK Ltd) res41: Other ADDs Multilex drug
74665020 Mirtazapine 30mg orodispersible tablets (Actavis UK Ltd) res41: Other ADDs Multilex drug
74668020 Mirtazapine 45mg orodispersible tablets (Actavis UK Ltd) res41: Other ADDs Multilex drug
74684020 Mirtazapine 15mg orodispersible tablets (Focus Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
74689020 Mirtazapine 45mg orodispersible tablets (Focus Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
74702020 Mirtazapine 15mg orodispersible tablets (A A H Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
74705020 Mirtazapine 30mg orodispersible tablets (A A H Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
74708020 Mirtazapine 45mg orodispersible tablets (A A H Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
74967020 Mirtazapine 15mg orodispersible tablets (Genus Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
74977020 Mirtazapine 45mg orodispersible tablets (Genus Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
75309020 Mirtazapine 15mg tablets (Teva UK Ltd) res41: Other ADDs Multilex drug
76425020 Mirtazapine 15mg tablets (Actavis UK Ltd) res41: Other ADDs Multilex drug
76512020 Mirtazapine 15mg orodispersible tablets (Aurobindo Pharma Ltd) res41: Other ADDs Multilex drug
78577020 Mirtazapine 30mg orodispersible tablets (Almus Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
84955020 Reboxetine 4mg tablets res41: Other ADDs Multilex drug
84961020 Edronax 4mg tablets (Pfizer Ltd) res41: Other ADDs Multilex drug
85108020 Venlafaxine 75mg modified-release capsules res41: Other ADDs Multilex drug
85109020 Venlafaxine 150mg modified-release capsules res41: Other ADDs Multilex drug
85163020 Efexor XL 75mg capsules (Pfizer Ltd) res41: Other ADDs Multilex drug
85164020 Efexor XL 150mg capsules (Pfizer Ltd) res41: Other ADDs Multilex drug
85247020 Mirtazapine 30mg tablets res41: Other ADDs Multilex drug
85251020 Zispin 30mg tablets (Organon Laboratories Ltd) res41: Other ADDs Multilex drug
86969020 Mirtazapine 30mg orodispersible tablets res41: Other ADDs Multilex drug
86971020 Zispin SolTab 30mg orodispersible tablets (Merck Sharp & Dohme Ltd) res41: Other ADDs Multilex drug
87476020 Mirtazapine 15mg orodispersible tablets res41: Other ADDs Multilex drug
87478020 Mirtazapine 45mg orodispersible tablets res41: Other ADDs Multilex drug
87480020 Zispin SolTab 15mg orodispersible tablets (Merck Sharp & Dohme Ltd) res41: Other ADDs Multilex drug
87482020 Zispin SolTab 45mg orodispersible tablets (Merck Sharp & Dohme Ltd) res41: Other ADDs Multilex drug
87990020 Mirtazapine 15mg/ml oral solution sugar free res41: Other ADDs Multilex drug
88845020 Duloxetine 30mg gastro-resistant capsules res41: Other ADDs Multilex drug
88847020 Duloxetine 60mg gastro-resistant capsules res41: Other ADDs Multilex drug
88849020 Cymbalta 30mg gastro-resistant capsules (Eli Lilly and Company Ltd) res41: Other ADDs Multilex drug
88851020 Cymbalta 60mg gastro-resistant capsules (Eli Lilly and Company Ltd) res41: Other ADDs Multilex drug
88879020 Mirtazapine 15mg tablets res41: Other ADDs Multilex drug
88881020 Mirtazapine 45mg tablets res41: Other ADDs Multilex drug
89954020 Venlafaxine 37.5mg/5ml oral suspension res41: Other ADDs Multilex drug
96239020 Rodomel XL 75mg capsules (Teva UK Ltd) res41: Other ADDs Multilex drug
96241020 Rodomel XL 150mg capsules (Teva UK Ltd) res41: Other ADDs Multilex drug
96329020 Tardcaps XL 75mg capsules (IXL Pharma Ltd) res41: Other ADDs Multilex drug
96331020 Tardcaps XL 150mg capsules (IXL Pharma Ltd) res41: Other ADDs Multilex drug
96355020 Vensir XL 75mg capsules (Morningside Healthcare Ltd) res41: Other ADDs Multilex drug
96357020 Vensir XL 150mg capsules (Morningside Healthcare Ltd) res41: Other ADDs Multilex drug
96439020 ViePax 37.5mg tablets (Dexcel-Pharma Ltd) res41: Other ADDs Multilex drug
96441020 ViePax 75mg tablets (Dexcel-Pharma Ltd) res41: Other ADDs Multilex drug
96445020 Venlafaxine 75mg modified-release tablets res41: Other ADDs Multilex drug
96447020 Venlafaxine 150mg modified-release tablets res41: Other ADDs Multilex drug
96449020 ViePax XL 75mg tablets (Dexcel-Pharma Ltd) res41: Other ADDs Multilex drug
96451020 ViePax XL 150mg tablets (Dexcel-Pharma Ltd) res41: Other ADDs Multilex drug
96465020 Tifaxin XL 75mg capsules (Genus Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
96467020 Tifaxin XL 150mg capsules (Genus Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
96473020 Politid XL 75mg capsules (Actavis UK Ltd) res41: Other ADDs Multilex drug
96475020 Politid XL 150mg capsules (Actavis UK Ltd) res41: Other ADDs Multilex drug
96534020 Vexarin XL 75mg capsules (Generics (UK) Ltd) res41: Other ADDs Multilex drug
96536020 Vexarin XL 150mg capsules (Generics (UK) Ltd) res41: Other ADDs Multilex drug
96614020 Venlafaxine 75mg modified-release capsules (Sandoz Ltd) res41: Other ADDs Multilex drug
96616020 Venlafaxine 150mg modified-release capsules (Sandoz Ltd) res41: Other ADDs Multilex drug
96834020 Venlalic XL 75mg tablets (DB Ashbourne Ltd) res41: Other ADDs Multilex drug
96836020 Venlalic XL 150mg tablets (DB Ashbourne Ltd) res41: Other ADDs Multilex drug
96838020 Venlafaxine 225mg modified-release tablets res41: Other ADDs Multilex drug
96841020 Venlalic XL 225mg tablets (DB Ashbourne Ltd) res41: Other ADDs Multilex drug
97003020 Venaxx XL 75mg capsules (AMCo) res41: Other ADDs Multilex drug
97005020 Venaxx XL 150mg capsules (AMCo) res41: Other ADDs Multilex drug
97028020 Agomelatine 25mg tablets res41: Other ADDs Multilex drug
97030020 Valdoxan 25mg tablets (Servier Laboratories Ltd) res41: Other ADDs Multilex drug
97351020 Foraven XL 75mg capsules (Forum Products Ltd) res41: Other ADDs Multilex drug
97656020 Ranfaxine XL 75mg capsules (Ranbaxy (UK) Ltd) res41: Other ADDs Multilex drug
98348020 Tonpular XL 75mg capsules (Wockhardt UK Ltd) res41: Other ADDs Multilex drug
98861020 Depefex XL 75mg capsules (Chiesi Ltd) res41: Other ADDs Multilex drug
98863020 Depefex XL 150mg capsules (Chiesi Ltd) res41: Other ADDs Multilex drug
9892020 Zispin SolTab 15mg orodispersible tablets (Necessity Supplies Ltd) res41: Other ADDs Multilex drug
9905020 Zispin SolTab 30mg orodispersible tablets (Necessity Supplies Ltd) res41: Other ADDs Multilex drug
99208020 Venlaneo XL 75mg capsules (Kent Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
99210020 Venlaneo XL 150mg capsules (Kent Pharmaceuticals Ltd) res41: Other ADDs Multilex drug
99679020 Venlafaxine 37.5mg modified-release tablets res41: Other ADDs Multilex drug
99681020 Venlalic XL 37.5mg tablets (DB Ashbourne Ltd) res41: Other ADDs Multilex drug

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH383/version/766/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH383/version/766/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH383', '766', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH383/version/766/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH383/version/766/export/codes/?format=json
CSV site_root/phenotypes/PH383/version/766/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH383', '766', api_client=client)

Version History

Version
ID
Name Owner Publish date
766 Other ADDs ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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